NAALAD2 (N-acetylated alpha-linked acidic dipeptidase 2)

2003-06-01  

Identity

HGNC
LOCATION
11q14.3
LOCUSID
ALIAS
GCPIII,GPCIII,NAADALASE2,NAALADASE2
FUSION GENES

Other Information

Locus ID:

NCBI: 10003
MIM: 611636
HGNC: 14526
Ensembl: ENSG00000077616

Variants:

dbSNP: 10003
ClinVar: 10003
TCGA: ENSG00000077616
COSMIC: NAALAD2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000077616ENST00000321955J3KNJ3
ENSG00000077616ENST00000375944Q9Y3Q0
ENSG00000077616ENST00000525171E9PKX5
ENSG00000077616ENST00000525497E9PII2
ENSG00000077616ENST00000526637E9PJ53
ENSG00000077616ENST00000527493E9PJV2
ENSG00000077616ENST00000534061Q9Y3Q0

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Amino acid synthesis and interconversion (transamination)REACTOMER-HSA-70614

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
119059942002Substrate specificity, inhibition and enzymological analysis of recombinant human glutamate carboxypeptidase II.28
122047972002Influence of a glutamate carboxypeptidase II (GCPII) polymorphism (1561C-->T) on plasma homocysteine, folate and vitamin B(12) levels and its relationship to cardiovascular disease risk.11
308447042019GCPII and its close homolog GCPIII: from a neuropeptidase to a cancer marker and beyond.0

Citation

Dessen P

NAALAD2 (N-acetylated alpha-linked acidic dipeptidase 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/41490/naalad2