Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NABP1 (nucleic acid binding protein 1)

Identity

Alias_namesOBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
Alias_symbol (synonym)FLJ22833
DKFZp667M1322
FLJ13624
MGC111163
SSB2
hSSB2
SOSS-B2
Other alias
HGNC (Hugo) NABP1
LocusID (NCBI) 64859
Atlas_Id 51114
Location 2q32.3  [Link to chromosome band 2q32]
Location_base_pair Starts at 191678135 and ends at 191688522 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NABP1 (2q32.3) / RARA (17q21.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 3 ]
  M3/M3v acute myeloid leukemia (AML M3/M3v)
::Acute promyelocytic leukemia (APL)
::Acute promyelocytic leukemia (APL) PML/RARA

t(2;17)(q32;q21) NABP1/RARA
t(5;17)(q35;q21) NPM1/RARA


External links

Nomenclature
HGNC (Hugo)NABP1   26232
Cards
Entrez_Gene (NCBI)NABP1  64859  nucleic acid binding protein 1
AliasesOBFC2A; SOSS-B2; SSB2
GeneCards (Weizmann)NABP1
Ensembl hg19 (Hinxton)ENSG00000173559 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173559 [Gene_View]  chr2:191678135-191688522 [Contig_View]  NABP1 [Vega]
ICGC DataPortalENSG00000173559
TCGA cBioPortalNABP1
AceView (NCBI)NABP1
Genatlas (Paris)NABP1
WikiGenes64859
SOURCE (Princeton)NABP1
Genetics Home Reference (NIH)NABP1
Genomic and cartography
GoldenPath hg38 (UCSC)NABP1  -     chr2:191678135-191688522 +  2q32.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NABP1  -     2q32.3   [Description]    (hg19-Feb_2009)
EnsemblNABP1 - 2q32.3 [CytoView hg19]  NABP1 - 2q32.3 [CytoView hg38]
Mapping of homologs : NCBINABP1 [Mapview hg19]  NABP1 [Mapview hg38]
OMIM612103   
Gene and transcription
Genbank (Entrez)AK023686 AK026486 AL832659 AL833684 BC017114
RefSeq transcript (Entrez)NM_001031716 NM_001254736 NM_022837
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NABP1
Cluster EST : UnigeneHs.591610 [ NCBI ]
CGAP (NCI)Hs.591610
Alternative Splicing GalleryENSG00000173559
Gene ExpressionNABP1 [ NCBI-GEO ]   NABP1 [ EBI - ARRAY_EXPRESS ]   NABP1 [ SEEK ]   NABP1 [ MEM ]
Gene Expression Viewer (FireBrowse)NABP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64859
GTEX Portal (Tissue expression)NABP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96AH0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96AH0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96AH0
Splice isoforms : SwissVarQ96AH0
PhosPhoSitePlusQ96AH0
Domains : Interpro (EBI)NA-bd_OB-fold    SOSS-B2   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)NABP1
DMDM Disease mutations64859
Blocks (Seattle)NABP1
SuperfamilyQ96AH0
Human Protein AtlasENSG00000173559
Peptide AtlasQ96AH0
HPRD08009
IPIIPI00059434   IPI00892743   IPI00010228   IPI00916576   IPI00915759   
Protein Interaction databases
DIP (DOE-UCLA)Q96AH0
IntAct (EBI)Q96AH0
FunCoupENSG00000173559
BioGRIDNABP1
STRING (EMBL)NABP1
ZODIACNABP1
Ontologies - Pathways
QuickGOQ96AH0
Ontology : AmiGOdouble-strand break repair via homologous recombination  nuclear chromosome, telomeric region  single-stranded DNA binding  RNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  cytosol  DNA repair  cellular response to DNA damage stimulus  mitotic cell cycle checkpoint  response to ionizing radiation  snRNA transcription from RNA polymerase II promoter  SOSS complex  
Ontology : EGO-EBIdouble-strand break repair via homologous recombination  nuclear chromosome, telomeric region  single-stranded DNA binding  RNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  cytosol  DNA repair  cellular response to DNA damage stimulus  mitotic cell cycle checkpoint  response to ionizing radiation  snRNA transcription from RNA polymerase II promoter  SOSS complex  
NDEx NetworkNABP1
Atlas of Cancer Signalling NetworkNABP1
Wikipedia pathwaysNABP1
Orthology - Evolution
OrthoDB64859
GeneTree (enSembl)ENSG00000173559
Phylogenetic Trees/Animal Genes : TreeFamNABP1
HOVERGENQ96AH0
HOGENOMQ96AH0
Homologs : HomoloGeneNABP1
Homology/Alignments : Family Browser (UCSC)NABP1
Gene fusions - Rearrangements
Fusion : MitelmanNABP1/RARA [2q32.3/17q21.2]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNABP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NABP1
dbVarNABP1
ClinVarNABP1
1000_GenomesNABP1 
Exome Variant ServerNABP1
ExAC (Exome Aggregation Consortium)NABP1 (select the gene name)
Genetic variants : HAPMAP64859
Genomic Variants (DGV)NABP1 [DGVbeta]
DECIPHERNABP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNABP1 
Mutations
ICGC Data PortalNABP1 
TCGA Data PortalNABP1 
Broad Tumor PortalNABP1
OASIS PortalNABP1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDNABP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NABP1
DgiDB (Drug Gene Interaction Database)NABP1
DoCM (Curated mutations)NABP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NABP1 (select a term)
intoGenNABP1
Cancer3DNABP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612103   
Orphanet8559   
MedgenNABP1
Genetic Testing Registry NABP1
NextProtQ96AH0 [Medical]
TSGene64859
GENETestsNABP1
Target ValidationNABP1
Huge Navigator NABP1 [HugePedia]
snp3D : Map Gene to Disease64859
BioCentury BCIQNABP1
ClinGenNABP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64859
Chemical/Pharm GKB GenePA143485566
Clinical trialNABP1
Miscellaneous
canSAR (ICR)NABP1 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNABP1
EVEXNABP1
GoPubMedNABP1
iHOPNABP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 14:01:05 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.