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NACC2 (NACC family member 2)

Identity

Alias_namesBTBD14A
BTB (POZ) domain containing 14A
NACC family member 2, BEN and BTB (POZ) domain containing
Alias_symbol (synonym)MGC23427
BEND9
BTBD31
Other aliasBTBD14
NAC-2
RBB
HGNC (Hugo) NACC2
LocusID (NCBI) 138151
Atlas_Id 54015
Location 9q34.3  [Link to chromosome band 9q34]
Location_base_pair Starts at 138898383 and ends at 138987131 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
NACC2 (9q34.3) / NTRK2 (9q21.33)TJAP1 (6p21.1) / NACC2 (9q34.3)NACC2 9q34.3 / NTRK2 9q21.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NACC2   23846
Cards
Entrez_Gene (NCBI)NACC2  138151  NACC family member 2
AliasesBEND9; BTBD14; BTBD14A; BTBD31; 
NAC-2; RBB
GeneCards (Weizmann)NACC2
Ensembl hg19 (Hinxton)ENSG00000148411 [Gene_View]  chr9:138898383-138987131 [Contig_View]  NACC2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000148411 [Gene_View]  chr9:138898383-138987131 [Contig_View]  NACC2 [Vega]
ICGC DataPortalENSG00000148411
TCGA cBioPortalNACC2
AceView (NCBI)NACC2
Genatlas (Paris)NACC2
WikiGenes138151
SOURCE (Princeton)NACC2
Genetics Home Reference (NIH)NACC2
Genomic and cartography
GoldenPath hg19 (UCSC)NACC2  -     chr9:138898383-138987131 -  9q34.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NACC2  -     9q34.3   [Description]    (hg38-Dec_2013)
EnsemblNACC2 - 9q34.3 [CytoView hg19]  NACC2 - 9q34.3 [CytoView hg38]
Mapping of homologs : NCBINACC2 [Mapview hg19]  NACC2 [Mapview hg38]
OMIM615786   
Gene and transcription
Genbank (Entrez)AK055078 AK056521 AK094914 AK308497 AK309247
RefSeq transcript (Entrez)NM_144653
RefSeq genomic (Entrez)NC_000009 NC_018920 NT_008470 NW_004929368
Consensus coding sequences : CCDS (NCBI)NACC2
Cluster EST : UnigeneHs.736561 [ NCBI ]
CGAP (NCI)Hs.736561
Alternative Splicing GalleryENSG00000148411
Gene ExpressionNACC2 [ NCBI-GEO ]   NACC2 [ EBI - ARRAY_EXPRESS ]   NACC2 [ SEEK ]   NACC2 [ MEM ]
Gene Expression Viewer (FireBrowse)NACC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)138151
GTEX Portal (Tissue expression)NACC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96BF6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96BF6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96BF6
Splice isoforms : SwissVarQ96BF6
PhosPhoSitePlusQ96BF6
Domaine pattern : Prosite (Expaxy)BEN (PS51457)    BTB (PS50097)   
Domains : Interpro (EBI)BEN_domain    BTB/POZ_dom    SKP1/BTB/POZ   
Domain families : Pfam (Sanger)BEN (PF10523)    BTB (PF00651)   
Domain families : Pfam (NCBI)pfam10523    pfam00651   
Domain families : Smart (EMBL)BEN (SM01025)  BTB (SM00225)  
Conserved Domain (NCBI)NACC2
DMDM Disease mutations138151
Blocks (Seattle)NACC2
SuperfamilyQ96BF6
Human Protein AtlasENSG00000148411
Peptide AtlasQ96BF6
HPRD09831
IPIIPI00059930   
Protein Interaction databases
DIP (DOE-UCLA)Q96BF6
IntAct (EBI)Q96BF6
FunCoupENSG00000148411
BioGRIDNACC2
STRING (EMBL)NACC2
ZODIACNACC2
Ontologies - Pathways
QuickGOQ96BF6
Ontology : AmiGOnuclear chromatin  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcription factor activity, RNA polymerase II transcription factor binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  histone deacetylase activity  protein binding  nucleus  nucleus  transcription, DNA-templated  positive regulation of cell proliferation  negative regulation of cell proliferation  posttranscriptional regulation of gene expression  histone deacetylation  NuRD complex  nuclear body  cellular protein complex localization  protein homodimerization activity  histone deacetylase binding  negative regulation of transcription, DNA-templated  negative regulation of transcription, DNA-templated  protein homooligomerization  protein homooligomerization  negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter  positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage  
Ontology : EGO-EBInuclear chromatin  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcription factor activity, RNA polymerase II transcription factor binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  histone deacetylase activity  protein binding  nucleus  nucleus  transcription, DNA-templated  positive regulation of cell proliferation  negative regulation of cell proliferation  posttranscriptional regulation of gene expression  histone deacetylation  NuRD complex  nuclear body  cellular protein complex localization  protein homodimerization activity  histone deacetylase binding  negative regulation of transcription, DNA-templated  negative regulation of transcription, DNA-templated  protein homooligomerization  protein homooligomerization  negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter  positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage  
NDEx NetworkNACC2
Atlas of Cancer Signalling NetworkNACC2
Wikipedia pathwaysNACC2
Orthology - Evolution
OrthoDB138151
GeneTree (enSembl)ENSG00000148411
Phylogenetic Trees/Animal Genes : TreeFamNACC2
HOVERGENQ96BF6
HOGENOMQ96BF6
Homologs : HomoloGeneNACC2
Homology/Alignments : Family Browser (UCSC)NACC2
Gene fusions - Rearrangements
Fusion : MitelmanNACC2/NTRK2 [9q34.3/9q21.33]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNACC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NACC2
dbVarNACC2
ClinVarNACC2
1000_GenomesNACC2 
Exome Variant ServerNACC2
ExAC (Exome Aggregation Consortium)NACC2 (select the gene name)
Genetic variants : HAPMAP138151
Genomic Variants (DGV)NACC2 [DGVbeta]
DECIPHER (Syndromes)9:138898383-138987131  ENSG00000148411
CONAN: Copy Number AnalysisNACC2 
Mutations
ICGC Data PortalNACC2 
TCGA Data PortalNACC2 
Broad Tumor PortalNACC2
OASIS PortalNACC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNACC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNACC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NACC2
DgiDB (Drug Gene Interaction Database)NACC2
DoCM (Curated mutations)NACC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NACC2 (select a term)
intoGenNACC2
Cancer3DNACC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615786   
Orphanet
MedgenNACC2
Genetic Testing Registry NACC2
NextProtQ96BF6 [Medical]
TSGene138151
GENETestsNACC2
Huge Navigator NACC2 [HugePedia]
snp3D : Map Gene to Disease138151
BioCentury BCIQNACC2
ClinGenNACC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD138151
Chemical/Pharm GKB GenePA164723421
Clinical trialNACC2
Miscellaneous
canSAR (ICR)NACC2 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNACC2
EVEXNACC2
GoPubMedNACC2
iHOPNACC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:11:36 CEST 2017

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