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NADK2 (NAD kinase 2, mitochondrial)

Identity

Alias (NCBI)C5orf33
DECRD
MNADK
NADKD1
HGNC (Hugo) NADK2
HGNC Alias symbFLJ30596
MNADK
HGNC Alias namemitochondrial NAD kinase
HGNC Previous nameC5orf33
 NADKD1
HGNC Previous namechromosome 5 open reading frame 33
 NAD kinase domain containing 1
LocusID (NCBI) 133686
Atlas_Id 53303
Location 5p13.2  [Link to chromosome band 5p13]
Location_base_pair Starts at 36192589 and ends at 36242279 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AKAP9 (7q21.2) / NADK2 (5p13.2)NADK2 (5p13.2) / BRD2 (6p21.32)NADK2 (5p13.2) / CMIP (16q23.2)
NADK2 (5p13.2) / DONSON (21q22.11)NADK2 (5p13.2) / TPRN (9q34.3)SPEF2 (5p13.2) / NADK2 (5p13.2)
TRIB3 (20p13) / NADK2 (5p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)NADK2   26404
Cards
Entrez_Gene (NCBI)NADK2    NAD kinase 2, mitochondrial
AliasesC5orf33; DECRD; MNADK; NADKD1
GeneCards (Weizmann)NADK2
Ensembl hg19 (Hinxton)ENSG00000152620 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000152620 [Gene_View]  ENSG00000152620 [Sequence]  chr5:36192589-36242279 [Contig_View]  NADK2 [Vega]
ICGC DataPortalENSG00000152620
TCGA cBioPortalNADK2
AceView (NCBI)NADK2
Genatlas (Paris)NADK2
SOURCE (Princeton)NADK2
Genetics Home Reference (NIH)NADK2
Genomic and cartography
GoldenPath hg38 (UCSC)NADK2  -     chr5:36192589-36242279 -  5p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NADK2  -     5p13.2   [Description]    (hg19-Feb_2009)
GoldenPathNADK2 - 5p13.2 [CytoView hg19]  NADK2 - 5p13.2 [CytoView hg38]
ImmunoBaseENSG00000152620
genome Data Viewer NCBINADK2 [Mapview hg19]  
OMIM615787   616034   
Gene and transcription
Genbank (Entrez)AA332693 AI377881 AK055158 AK057950 AK304009
RefSeq transcript (Entrez)NM_001085411 NM_001287340 NM_001287341 NM_153013
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NADK2
Alternative Splicing GalleryENSG00000152620
Gene ExpressionNADK2 [ NCBI-GEO ]   NADK2 [ EBI - ARRAY_EXPRESS ]   NADK2 [ SEEK ]   NADK2 [ MEM ]
Gene Expression Viewer (FireBrowse)NADK2 [ Firebrowse - Broad ]
GenevisibleExpression of NADK2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)133686
GTEX Portal (Tissue expression)NADK2
Human Protein AtlasENSG00000152620-NADK2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ4G0N4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ4G0N4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ4G0N4
Splice isoforms : SwissVarQ4G0N4
Catalytic activity : Enzyme2.7.1.23 [ Enzyme-Expasy ]   2.7.1.232.7.1.23 [ IntEnz-EBI ]   2.7.1.23 [ BRENDA ]   2.7.1.23 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ4G0N4
Domains : Interpro (EBI)ATP-NAD_kinase_N    ATP-NAD_kinase_PpnK-typ_C    NAD/diacylglycerol_kinase_sf    NADK    NADK2_mit   
Domain families : Pfam (Sanger)NAD_kinase (PF01513)   
Domain families : Pfam (NCBI)pfam01513   
Conserved Domain (NCBI)NADK2
Blocks (Seattle)NADK2
SuperfamilyQ4G0N4
Human Protein Atlas [tissue]ENSG00000152620-NADK2 [tissue]
Peptide AtlasQ4G0N4
HPRD08088
IPIIPI00845432   IPI00431405   IPI00654793   IPI00964640   IPI00964333   IPI00968110   
Protein Interaction databases
DIP (DOE-UCLA)Q4G0N4
IntAct (EBI)Q4G0N4
BioGRIDNADK2
STRING (EMBL)NADK2
ZODIACNADK2
Ontologies - Pathways
QuickGOQ4G0N4
Ontology : AmiGONAD+ kinase activity  NAD+ kinase activity  ATP binding  mitochondrion  mitochondrion  mitochondrial matrix  NADP biosynthetic process  phosphorylation  NAD metabolic process  NAD metabolic process  NAD metabolic process  protein homodimerization activity  
Ontology : EGO-EBINAD+ kinase activity  NAD+ kinase activity  ATP binding  mitochondrion  mitochondrion  mitochondrial matrix  NADP biosynthetic process  phosphorylation  NAD metabolic process  NAD metabolic process  NAD metabolic process  protein homodimerization activity  
NDEx NetworkNADK2
Atlas of Cancer Signalling NetworkNADK2
Wikipedia pathwaysNADK2
Orthology - Evolution
OrthoDB133686
GeneTree (enSembl)ENSG00000152620
Phylogenetic Trees/Animal Genes : TreeFamNADK2
HOGENOMQ4G0N4
Homologs : HomoloGeneNADK2
Homology/Alignments : Family Browser (UCSC)NADK2
Gene fusions - Rearrangements
Fusion : MitelmanSPEF2/NADK2 [5p13.2/5p13.2]  
Fusion : QuiverNADK2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNADK2 [hg38]
dbVarNADK2
ClinVarNADK2
MonarchNADK2
1000_GenomesNADK2 
Exome Variant ServerNADK2
GNOMAD BrowserENSG00000152620
Varsome BrowserNADK2
Genomic Variants (DGV)NADK2 [DGVbeta]
DECIPHERNADK2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNADK2 
Mutations
ICGC Data PortalNADK2 
TCGA Data PortalNADK2 
Broad Tumor PortalNADK2
OASIS PortalNADK2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNADK2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNADK2
Mutations and Diseases : HGMDNADK2
BioMutasearch NADK2
DgiDB (Drug Gene Interaction Database)NADK2
DoCM (Curated mutations)NADK2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NADK2 (select a term)
intoGenNADK2
Cancer3DNADK2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615787    616034   
Orphanet23249   
DisGeNETNADK2
MedgenNADK2
Genetic Testing Registry NADK2
NextProtQ4G0N4 [Medical]
GENETestsNADK2
Target ValidationNADK2
Huge Navigator NADK2 [HugePedia]
ClinGenNADK2
Clinical trials, drugs, therapy
MyCancerGenomeNADK2
Protein Interactions : CTD
Pharm GKB GenePA162380039
PharosQ4G0N4
Clinical trialNADK2
Miscellaneous
canSAR (ICR)NADK2 (select the gene name)
HarmonizomeNADK2
DataMed IndexNADK2
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNADK2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:35:39 CET 2021

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