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NADSYN1 (NAD synthetase 1)

Identity

Alias_symbol (synonym)FLJ10631
Other alias-
HGNC (Hugo) NADSYN1
LocusID (NCBI) 55191
Atlas_Id 70670
Location 11q13.4  [Link to chromosome band 11q13]
Location_base_pair Starts at 71164217 and ends at 71212581 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GSTA4 (6p12.2) / NADSYN1 (11q13.4)LRCH1 (13q14.13) / NADSYN1 (11q13.4)NADSYN1 (11q13.4) / HNRNPUL1 (19q13.2)
NADSYN1 (11q13.4) / MTL5 (11q13.3)NADSYN1 (11q13.4) / NADSYN1 (11q13.4)NADSYN1 (11q13.4) / PLET1 (11q23.1)
NADSYN1 (11q13.4) / TRIM9 (14q22.1)RELT (11q13.4) / NADSYN1 (11q13.4)SPTBN1 (2p16.2) / NADSYN1 (11q13.4)
SUPT5H (19q13.2) / NADSYN1 (11q13.4)ZNF451 (6p12.1) / NADSYN1 (11q13.4)GSTA4 NADSYN1
ZNF451 NADSYN1SUPT5H NADSYN1NADSYN1 TRIM9
NADSYN1 C11orf34

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NADSYN1   29832
Cards
Entrez_Gene (NCBI)NADSYN1  55191  NAD synthetase 1
Aliases
GeneCards (Weizmann)NADSYN1
Ensembl hg19 (Hinxton)ENSG00000172890 [Gene_View]  chr11:71164217-71212581 [Contig_View]  NADSYN1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000172890 [Gene_View]  chr11:71164217-71212581 [Contig_View]  NADSYN1 [Vega]
ICGC DataPortalENSG00000172890
TCGA cBioPortalNADSYN1
AceView (NCBI)NADSYN1
Genatlas (Paris)NADSYN1
WikiGenes55191
SOURCE (Princeton)NADSYN1
Genetics Home Reference (NIH)NADSYN1
Genomic and cartography
GoldenPath hg19 (UCSC)NADSYN1  -     chr11:71164217-71212581 +  11q13.4   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NADSYN1  -     11q13.4   [Description]    (hg38-Dec_2013)
EnsemblNADSYN1 - 11q13.4 [CytoView hg19]  NADSYN1 - 11q13.4 [CytoView hg38]
Mapping of homologs : NCBINADSYN1 [Mapview hg19]  NADSYN1 [Mapview hg38]
OMIM608285   
Gene and transcription
Genbank (Entrez)AB091316 AK001493 AK022436 AK055452 AK094022
RefSeq transcript (Entrez)NM_018161
RefSeq genomic (Entrez)NC_000011 NC_018922 NT_167190 NW_004929380
Consensus coding sequences : CCDS (NCBI)NADSYN1
Cluster EST : UnigeneHs.556986 [ NCBI ]
CGAP (NCI)Hs.556986
Alternative Splicing GalleryENSG00000172890
Gene ExpressionNADSYN1 [ NCBI-GEO ]   NADSYN1 [ EBI - ARRAY_EXPRESS ]   NADSYN1 [ SEEK ]   NADSYN1 [ MEM ]
Gene Expression Viewer (FireBrowse)NADSYN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55191
GTEX Portal (Tissue expression)NADSYN1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6IA69   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6IA69  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6IA69
Splice isoforms : SwissVarQ6IA69
Catalytic activity : Enzyme6.3.5.1 [ Enzyme-Expasy ]   6.3.5.16.3.5.1 [ IntEnz-EBI ]   6.3.5.1 [ BRENDA ]   6.3.5.1 [ KEGG ]   
PhosPhoSitePlusQ6IA69
Domaine pattern : Prosite (Expaxy)CN_HYDROLASE (PS50263)   
Domains : Interpro (EBI)C-N_Hydrolase    Gln-dep_NAD_synthase    NAD/GMP_synthase    NAD_synthase    Rossmann-like_a/b/a_fold   
Domain families : Pfam (Sanger)CN_hydrolase (PF00795)    NAD_synthase (PF02540)   
Domain families : Pfam (NCBI)pfam00795    pfam02540   
Conserved Domain (NCBI)NADSYN1
DMDM Disease mutations55191
Blocks (Seattle)NADSYN1
SuperfamilyQ6IA69
Human Protein AtlasENSG00000172890
Peptide AtlasQ6IA69
HPRD16309
IPIIPI00306689   IPI00976755   IPI00985281   IPI00979121   IPI00977364   IPI00976232   IPI00980972   IPI00979824   IPI00980326   IPI00978592   
Protein Interaction databases
DIP (DOE-UCLA)Q6IA69
IntAct (EBI)Q6IA69
FunCoupENSG00000172890
BioGRIDNADSYN1
STRING (EMBL)NADSYN1
ZODIACNADSYN1
Ontologies - Pathways
QuickGOQ6IA69
Ontology : AmiGONAD+ synthase (glutamine-hydrolyzing) activity  protein binding  ATP binding  cytoplasm  cytosol  vitamin metabolic process  water-soluble vitamin metabolic process  NAD biosynthetic process  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds  NAD metabolic process  small molecule metabolic process  
Ontology : EGO-EBINAD+ synthase (glutamine-hydrolyzing) activity  protein binding  ATP binding  cytoplasm  cytosol  vitamin metabolic process  water-soluble vitamin metabolic process  NAD biosynthetic process  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds  NAD metabolic process  small molecule metabolic process  
Pathways : KEGGNicotinate and nicotinamide metabolism   
NDEx NetworkNADSYN1
Atlas of Cancer Signalling NetworkNADSYN1
Wikipedia pathwaysNADSYN1
Orthology - Evolution
OrthoDB55191
GeneTree (enSembl)ENSG00000172890
Phylogenetic Trees/Animal Genes : TreeFamNADSYN1
HOVERGENQ6IA69
HOGENOMQ6IA69
Homologs : HomoloGeneNADSYN1
Homology/Alignments : Family Browser (UCSC)NADSYN1
Gene fusions - Rearrangements
Fusion: TCGAGSTA4 NADSYN1
Fusion: TCGAZNF451 NADSYN1
Fusion: TCGASUPT5H NADSYN1
Fusion: TCGANADSYN1 TRIM9
Fusion: TCGANADSYN1 C11orf34
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNADSYN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NADSYN1
dbVarNADSYN1
ClinVarNADSYN1
1000_GenomesNADSYN1 
Exome Variant ServerNADSYN1
ExAC (Exome Aggregation Consortium)NADSYN1 (select the gene name)
Genetic variants : HAPMAP55191
Genomic Variants (DGV)NADSYN1 [DGVbeta]
DECIPHER (Syndromes)11:71164217-71212581  ENSG00000172890
CONAN: Copy Number AnalysisNADSYN1 
Mutations
ICGC Data PortalNADSYN1 
TCGA Data PortalNADSYN1 
Broad Tumor PortalNADSYN1
OASIS PortalNADSYN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNADSYN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNADSYN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NADSYN1
DgiDB (Drug Gene Interaction Database)NADSYN1
DoCM (Curated mutations)NADSYN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NADSYN1 (select a term)
intoGenNADSYN1
Cancer3DNADSYN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608285   
Orphanet
MedgenNADSYN1
Genetic Testing Registry NADSYN1
NextProtQ6IA69 [Medical]
TSGene55191
GENETestsNADSYN1
Huge Navigator NADSYN1 [HugePedia]
snp3D : Map Gene to Disease55191
BioCentury BCIQNADSYN1
ClinGenNADSYN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55191
Chemical/Pharm GKB GenePA142671299
Clinical trialNADSYN1
Miscellaneous
canSAR (ICR)NADSYN1 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNADSYN1
EVEXNADSYN1
GoPubMedNADSYN1
iHOPNADSYN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:34:27 CET 2017

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