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NAGS (N-acetylglutamate synthase)

Identity

Alias_symbol (synonym)AGAS
ARGA
NAT7
Other alias
HGNC (Hugo) NAGS
LocusID (NCBI) 162417
Atlas_Id 70677
Location 17q21.31  [Link to chromosome band 17q21]
Location_base_pair Starts at 44004664 and ends at 44009068 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NAGS (17q21.31) / LIN54 (4q21.22)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NAGS   17996
Cards
Entrez_Gene (NCBI)NAGS  162417  N-acetylglutamate synthase
AliasesAGAS; ARGA
GeneCards (Weizmann)NAGS
Ensembl hg19 (Hinxton)ENSG00000161653 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000161653 [Gene_View]  chr17:44004664-44009068 [Contig_View]  NAGS [Vega]
ICGC DataPortalENSG00000161653
TCGA cBioPortalNAGS
AceView (NCBI)NAGS
Genatlas (Paris)NAGS
WikiGenes162417
SOURCE (Princeton)NAGS
Genetics Home Reference (NIH)NAGS
Genomic and cartography
GoldenPath hg38 (UCSC)NAGS  -     chr17:44004664-44009068 +  17q21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NAGS  -     17q21.31   [Description]    (hg19-Feb_2009)
EnsemblNAGS - 17q21.31 [CytoView hg19]  NAGS - 17q21.31 [CytoView hg38]
Mapping of homologs : NCBINAGS [Mapview hg19]  NAGS [Mapview hg38]
OMIM237310   608300   
Gene and transcription
Genbank (Entrez)AI241153 AK074407 AK091938 AK300923 AK314432
RefSeq transcript (Entrez)NM_153006
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NAGS
Cluster EST : UnigeneHs.8876 [ NCBI ]
CGAP (NCI)Hs.8876
Alternative Splicing GalleryENSG00000161653
Gene ExpressionNAGS [ NCBI-GEO ]   NAGS [ EBI - ARRAY_EXPRESS ]   NAGS [ SEEK ]   NAGS [ MEM ]
Gene Expression Viewer (FireBrowse)NAGS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)162417
GTEX Portal (Tissue expression)NAGS
Human Protein AtlasENSG00000161653-NAGS [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N159   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N159  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N159
Splice isoforms : SwissVarQ8N159
Catalytic activity : Enzyme2.3.1.1 [ Enzyme-Expasy ]   2.3.1.12.3.1.1 [ IntEnz-EBI ]   2.3.1.1 [ BRENDA ]   2.3.1.1 [ KEGG ]   
PhosPhoSitePlusQ8N159
Domaine pattern : Prosite (Expaxy)GNAT_NAGS (PS51731)   
Domains : Interpro (EBI)Acyl_CoA_acyltransferase    Asp/Glu/Uridylate_kinase    GlcNAc_Synth_met    Vertebrate-like_GNAT_dom   
Domain families : Pfam (Sanger)NAT (PF04768)   
Domain families : Pfam (NCBI)pfam04768   
Conserved Domain (NCBI)NAGS
DMDM Disease mutations162417
Blocks (Seattle)NAGS
PDB (SRS)4K30   
PDB (PDBSum)4K30   
PDB (IMB)4K30   
PDB (RSDB)4K30   
Structural Biology KnowledgeBase4K30   
SCOP (Structural Classification of Proteins)4K30   
CATH (Classification of proteins structures)4K30   
SuperfamilyQ8N159
Human Protein Atlas [tissue]ENSG00000161653-NAGS [tissue]
Peptide AtlasQ8N159
HPRD10510
IPIIPI00166092   IPI01010623   
Protein Interaction databases
DIP (DOE-UCLA)Q8N159
IntAct (EBI)Q8N159
FunCoupENSG00000161653
BioGRIDNAGS
STRING (EMBL)NAGS
ZODIACNAGS
Ontologies - Pathways
QuickGOQ8N159
Ontology : AmiGOurea cycle  acetylglutamate kinase activity  acetyl-CoA:L-glutamate N-acetyltransferase activity  acetyl-CoA:L-glutamate N-acetyltransferase activity  mitochondrion  mitochondrial matrix  arginine biosynthetic process  arginine biosynthetic process  glutamate metabolic process  arginine binding  
Ontology : EGO-EBIurea cycle  acetylglutamate kinase activity  acetyl-CoA:L-glutamate N-acetyltransferase activity  acetyl-CoA:L-glutamate N-acetyltransferase activity  mitochondrion  mitochondrial matrix  arginine biosynthetic process  arginine biosynthetic process  glutamate metabolic process  arginine binding  
Pathways : KEGGArginine and proline metabolism   
NDEx NetworkNAGS
Atlas of Cancer Signalling NetworkNAGS
Wikipedia pathwaysNAGS
Orthology - Evolution
OrthoDB162417
GeneTree (enSembl)ENSG00000161653
Phylogenetic Trees/Animal Genes : TreeFamNAGS
HOVERGENQ8N159
HOGENOMQ8N159
Homologs : HomoloGeneNAGS
Homology/Alignments : Family Browser (UCSC)NAGS
Gene fusions - Rearrangements
Fusion: Tumor Portal NAGS
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNAGS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NAGS
dbVarNAGS
ClinVarNAGS
1000_GenomesNAGS 
Exome Variant ServerNAGS
ExAC (Exome Aggregation Consortium)ENSG00000161653
GNOMAD BrowserENSG00000161653
Genetic variants : HAPMAP162417
Genomic Variants (DGV)NAGS [DGVbeta]
DECIPHERNAGS [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNAGS 
Mutations
ICGC Data PortalNAGS 
TCGA Data PortalNAGS 
Broad Tumor PortalNAGS
OASIS PortalNAGS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNAGS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNAGS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NAGS
DgiDB (Drug Gene Interaction Database)NAGS
DoCM (Curated mutations)NAGS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NAGS (select a term)
intoGenNAGS
Cancer3DNAGS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM237310    608300   
Orphanet3370   
MedgenNAGS
Genetic Testing Registry NAGS
NextProtQ8N159 [Medical]
TSGene162417
GENETestsNAGS
Target ValidationNAGS
Huge Navigator NAGS [HugePedia]
snp3D : Map Gene to Disease162417
BioCentury BCIQNAGS
ClinGenNAGS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD162417
Chemical/Pharm GKB GenePA134968729
Clinical trialNAGS
Miscellaneous
canSAR (ICR)NAGS (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNAGS
EVEXNAGS
GoPubMedNAGS
iHOPNAGS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:18:31 CET 2017

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