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NANOS1 (nanos C2HC-type zinc finger 1)

Identity

Alias (NCBI)EC_Rep1a
NOS-1
NOS1
SPGF12
ZC2HC12A
HGNC (Hugo) NANOS1
HGNC Alias symbNOS1
ZC2HC12A
HGNC Previous namenanos homolog 1 (Drosophila)
LocusID (NCBI) 340719
Atlas_Id 43992
Location 10q26.11  [Link to chromosome band 10q26]
Location_base_pair Starts at 119029714 and ends at 119033730 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)NANOS1   23044
Cards
Entrez_Gene (NCBI)NANOS1    nanos C2HC-type zinc finger 1
AliasesEC_Rep1a; NOS-1; NOS1; SPGF12; 
ZC2HC12A
GeneCards (Weizmann)NANOS1
Ensembl hg19 (Hinxton)ENSG00000188613 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188613 [Gene_View]  ENSG00000188613 [Sequence]  chr10:119029714-119033730 [Contig_View]  NANOS1 [Vega]
ICGC DataPortalENSG00000188613
TCGA cBioPortalNANOS1
AceView (NCBI)NANOS1
Genatlas (Paris)NANOS1
SOURCE (Princeton)NANOS1
Genetics Home Reference (NIH)NANOS1
Genomic and cartography
GoldenPath hg38 (UCSC)NANOS1  -     chr10:119029714-119033730 +  10q26.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NANOS1  -     10q26.11   [Description]    (hg19-Feb_2009)
GoldenPathNANOS1 - 10q26.11 [CytoView hg19]  NANOS1 - 10q26.11 [CytoView hg38]
ImmunoBaseENSG00000188613
Genome Data Viewer NCBINANOS1 [Mapview hg19]  
OMIM608226   615413   
Gene and transcription
Genbank (Entrez)AF086393 AF275269 AF458985 AI276145
RefSeq transcript (Entrez)NM_001009553 NM_199461
Consensus coding sequences : CCDS (NCBI)NANOS1
Gene ExpressionNANOS1 [ NCBI-GEO ]   NANOS1 [ EBI - ARRAY_EXPRESS ]   NANOS1 [ SEEK ]   NANOS1 [ MEM ]
Gene Expression Viewer (FireBrowse)NANOS1 [ Firebrowse - Broad ]
GenevisibleExpression of NANOS1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)340719
GTEX Portal (Tissue expression)NANOS1
Human Protein AtlasENSG00000188613-NANOS1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WY41   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WY41  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WY41
PhosPhoSitePlusQ8WY41
Domaine pattern : Prosite (Expaxy)ZF_NANOS (PS51522)   
Domains : Interpro (EBI)Nanos/Xcar2    Nanos_sf    Znf_nanos-typ   
Domain families : Pfam (Sanger)zf-nanos (PF05741)   
Domain families : Pfam (NCBI)pfam05741   
Conserved Domain (NCBI)NANOS1
PDB (RSDB)4CQO   
PDB Europe4CQO   
PDB (PDBSum)4CQO   
PDB (IMB)4CQO   
Structural Biology KnowledgeBase4CQO   
SCOP (Structural Classification of Proteins)4CQO   
CATH (Classification of proteins structures)4CQO   
SuperfamilyQ8WY41
AlphaFold pdb e-kbQ8WY41   
Human Protein Atlas [tissue]ENSG00000188613-NANOS1 [tissue]
HPRD16302
Protein Interaction databases
DIP (DOE-UCLA)Q8WY41
IntAct (EBI)Q8WY41
BioGRIDNANOS1
STRING (EMBL)NANOS1
ZODIACNANOS1
Ontologies - Pathways
QuickGOQ8WY41
Ontology : AmiGOregulation of cell growth  tissue homeostasis  mRNA binding  protein binding  cytoplasm  zinc ion binding  posttranscriptional regulation of gene expression  epithelial cell migration  cell migration  negative regulation of translation  negative regulation of translation  translation repressor activity  perinuclear region of cytoplasm  perinuclear region of cytoplasm  oogenesis  cerebellar neuron development  positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  
Ontology : EGO-EBIregulation of cell growth  tissue homeostasis  mRNA binding  protein binding  cytoplasm  zinc ion binding  posttranscriptional regulation of gene expression  epithelial cell migration  cell migration  negative regulation of translation  negative regulation of translation  translation repressor activity  perinuclear region of cytoplasm  perinuclear region of cytoplasm  oogenesis  cerebellar neuron development  positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  
NDEx NetworkNANOS1
Atlas of Cancer Signalling NetworkNANOS1
Wikipedia pathwaysNANOS1
Orthology - Evolution
OrthoDB340719
GeneTree (enSembl)ENSG00000188613
Phylogenetic Trees/Animal Genes : TreeFamNANOS1
Homologs : HomoloGeneNANOS1
Homology/Alignments : Family Browser (UCSC)NANOS1
Gene fusions - Rearrangements
Fusion : QuiverNANOS1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNANOS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NANOS1
dbVarNANOS1
ClinVarNANOS1
MonarchNANOS1
1000_GenomesNANOS1 
Exome Variant ServerNANOS1
GNOMAD BrowserENSG00000188613
Varsome BrowserNANOS1
ACMGNANOS1 variants
VarityQ8WY41
Genomic Variants (DGV)NANOS1 [DGVbeta]
DECIPHERNANOS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNANOS1 
Mutations
ICGC Data PortalNANOS1 
TCGA Data PortalNANOS1 
Broad Tumor PortalNANOS1
OASIS PortalNANOS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNANOS1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNANOS1
Mutations and Diseases : HGMDNANOS1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNANOS1
DgiDB (Drug Gene Interaction Database)NANOS1
DoCM (Curated mutations)NANOS1
CIViC (Clinical Interpretations of Variants in Cancer)NANOS1
Cancer3DNANOS1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608226    615413   
Orphanet22775    22774   
DisGeNETNANOS1
MedgenNANOS1
Genetic Testing Registry NANOS1
NextProtQ8WY41 [Medical]
GENETestsNANOS1
Target ValidationNANOS1
Huge Navigator NANOS1 [HugePedia]
ClinGenNANOS1
Clinical trials, drugs, therapy
MyCancerGenomeNANOS1
Protein Interactions : CTDNANOS1
Pharm GKB GenePA134876543
PharosQ8WY41
Clinical trialNANOS1
Miscellaneous
canSAR (ICR)NANOS1
HarmonizomeNANOS1
DataMed IndexNANOS1
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNANOS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:22:01 CEST 2021
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