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NANOS2 (nanos C2HC-type zinc finger 2)

Identity

Alias_namesnanos homolog 2 (Drosophila)
Alias_symbol (synonym)NOS2
ZC2HC12B
Other alias
HGNC (Hugo) NANOS2
LocusID (NCBI) 339345
Atlas_Id 70683
Location 19q13.32  [Link to chromosome band 19q13]
Location_base_pair Starts at 45913215 and ends at 45914778 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NANOS2   23292
Cards
Entrez_Gene (NCBI)NANOS2  339345  nanos C2HC-type zinc finger 2
AliasesNOS2; ZC2HC12B
GeneCards (Weizmann)NANOS2
Ensembl hg19 (Hinxton)ENSG00000188425 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188425 [Gene_View]  chr19:45913215-45914778 [Contig_View]  NANOS2 [Vega]
ICGC DataPortalENSG00000188425
TCGA cBioPortalNANOS2
AceView (NCBI)NANOS2
Genatlas (Paris)NANOS2
WikiGenes339345
SOURCE (Princeton)NANOS2
Genetics Home Reference (NIH)NANOS2
Genomic and cartography
GoldenPath hg38 (UCSC)NANOS2  -     chr19:45913215-45914778 -  19q13.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NANOS2  -     19q13.32   [Description]    (hg19-Feb_2009)
EnsemblNANOS2 - 19q13.32 [CytoView hg19]  NANOS2 - 19q13.32 [CytoView hg38]
Mapping of homologs : NCBINANOS2 [Mapview hg19]  NANOS2 [Mapview hg38]
OMIM608228   
Gene and transcription
Genbank (Entrez)BC042883 BC117484 BC117486 HQ258065
RefSeq transcript (Entrez)NM_001029861
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NANOS2
Cluster EST : UnigeneHs.434218 [ NCBI ]
CGAP (NCI)Hs.434218
Alternative Splicing GalleryENSG00000188425
Gene ExpressionNANOS2 [ NCBI-GEO ]   NANOS2 [ EBI - ARRAY_EXPRESS ]   NANOS2 [ SEEK ]   NANOS2 [ MEM ]
Gene Expression Viewer (FireBrowse)NANOS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)339345
GTEX Portal (Tissue expression)NANOS2
Human Protein AtlasENSG00000188425-NANOS2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP60321   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP60321  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP60321
Splice isoforms : SwissVarP60321
PhosPhoSitePlusP60321
Domaine pattern : Prosite (Expaxy)ZF_NANOS (PS51522)   
Domains : Interpro (EBI)Nanos/Xcar2    Znf_nanos-typ   
Domain families : Pfam (Sanger)zf-nanos (PF05741)   
Domain families : Pfam (NCBI)pfam05741   
Conserved Domain (NCBI)NANOS2
DMDM Disease mutations339345
Blocks (Seattle)NANOS2
SuperfamilyP60321
Human Protein Atlas [tissue]ENSG00000188425-NANOS2 [tissue]
Peptide AtlasP60321
HPRD18784
IPIIPI00397723   
Protein Interaction databases
DIP (DOE-UCLA)P60321
IntAct (EBI)P60321
FunCoupENSG00000188425
BioGRIDNANOS2
STRING (EMBL)NANOS2
ZODIACNANOS2
Ontologies - Pathways
QuickGOP60321
Ontology : AmiGOP-body  mRNA binding  protein binding  nucleus  cytoplasm  mRNA catabolic process  multicellular organism development  spermatogenesis  zinc ion binding  negative regulation of translation  cell differentiation  germ-line stem cell population maintenance  negative regulation of meiotic nuclear division  perinuclear region of cytoplasm  positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  
Ontology : EGO-EBIP-body  mRNA binding  protein binding  nucleus  cytoplasm  mRNA catabolic process  multicellular organism development  spermatogenesis  zinc ion binding  negative regulation of translation  cell differentiation  germ-line stem cell population maintenance  negative regulation of meiotic nuclear division  perinuclear region of cytoplasm  positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  
NDEx NetworkNANOS2
Atlas of Cancer Signalling NetworkNANOS2
Wikipedia pathwaysNANOS2
Orthology - Evolution
OrthoDB339345
GeneTree (enSembl)ENSG00000188425
Phylogenetic Trees/Animal Genes : TreeFamNANOS2
HOVERGENP60321
HOGENOMP60321
Homologs : HomoloGeneNANOS2
Homology/Alignments : Family Browser (UCSC)NANOS2
Gene fusions - Rearrangements
Tumor Fusion PortalNANOS2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNANOS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NANOS2
dbVarNANOS2
ClinVarNANOS2
1000_GenomesNANOS2 
Exome Variant ServerNANOS2
ExAC (Exome Aggregation Consortium)ENSG00000188425
GNOMAD BrowserENSG00000188425
Genetic variants : HAPMAP339345
Genomic Variants (DGV)NANOS2 [DGVbeta]
DECIPHERNANOS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNANOS2 
Mutations
ICGC Data PortalNANOS2 
TCGA Data PortalNANOS2 
Broad Tumor PortalNANOS2
OASIS PortalNANOS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNANOS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNANOS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NANOS2
DgiDB (Drug Gene Interaction Database)NANOS2
DoCM (Curated mutations)NANOS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NANOS2 (select a term)
intoGenNANOS2
Cancer3DNANOS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608228   
Orphanet
DisGeNETNANOS2
MedgenNANOS2
Genetic Testing Registry NANOS2
NextProtP60321 [Medical]
TSGene339345
GENETestsNANOS2
Target ValidationNANOS2
Huge Navigator NANOS2 [HugePedia]
snp3D : Map Gene to Disease339345
BioCentury BCIQNANOS2
ClinGenNANOS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD339345
Chemical/Pharm GKB GenePA134909776
Clinical trialNANOS2
Miscellaneous
canSAR (ICR)NANOS2 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNANOS2
EVEXNANOS2
GoPubMedNANOS2
iHOPNANOS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:39:23 CET 2017

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