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NANOS3 (nanos C2HC-type zinc finger 3)

Identity

Alias (NCBI)NANOS1L
NOS3
ZC2HC12C
HGNC (Hugo) NANOS3
HGNC Alias symbNANOS1L
NOS3
ZC2HC12C
HGNC Previous namenanos homolog 3 (Drosophila)
LocusID (NCBI) 342977
Atlas_Id 55514
Location 19p13.12  [Link to chromosome band 19p13]
Location_base_pair Starts at 13877249 and ends at 13880757 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)NANOS3   22048
Cards
Entrez_Gene (NCBI)NANOS3    nanos C2HC-type zinc finger 3
AliasesNANOS1L; NOS3; ZC2HC12C
GeneCards (Weizmann)NANOS3
Ensembl hg19 (Hinxton)ENSG00000187556 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187556 [Gene_View]  ENSG00000187556 [Sequence]  chr19:13877249-13880757 [Contig_View]  NANOS3 [Vega]
ICGC DataPortalENSG00000187556
TCGA cBioPortalNANOS3
AceView (NCBI)NANOS3
Genatlas (Paris)NANOS3
SOURCE (Princeton)NANOS3
Genetics Home Reference (NIH)NANOS3
Genomic and cartography
GoldenPath hg38 (UCSC)NANOS3  -     chr19:13877249-13880757 +  19p13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NANOS3  -     19p13.12   [Description]    (hg19-Feb_2009)
GoldenPathNANOS3 - 19p13.12 [CytoView hg19]  NANOS3 - 19p13.12 [CytoView hg38]
ImmunoBaseENSG00000187556
Genome Data Viewer NCBINANOS3 [Mapview hg19]  
OMIM608229   
Gene and transcription
Genbank (Entrez)BC101209 BC101210 BI793167 BM702754 CK821051
RefSeq transcript (Entrez)NM_001098622
Consensus coding sequences : CCDS (NCBI)NANOS3
Gene ExpressionNANOS3 [ NCBI-GEO ]   NANOS3 [ EBI - ARRAY_EXPRESS ]   NANOS3 [ SEEK ]   NANOS3 [ MEM ]
Gene Expression Viewer (FireBrowse)NANOS3 [ Firebrowse - Broad ]
GenevisibleExpression of NANOS3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)342977
GTEX Portal (Tissue expression)NANOS3
Human Protein AtlasENSG00000187556-NANOS3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP60323   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP60323  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP60323
PhosPhoSitePlusP60323
Domaine pattern : Prosite (Expaxy)ZF_NANOS (PS51522)   
Domains : Interpro (EBI)Nanos/Xcar2    Nanos_sf    Znf_nanos-typ   
Domain families : Pfam (Sanger)zf-nanos (PF05741)   
Domain families : Pfam (NCBI)pfam05741   
Conserved Domain (NCBI)NANOS3
SuperfamilyP60323
AlphaFold pdb e-kbP60323   
Human Protein Atlas [tissue]ENSG00000187556-NANOS3 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)P60323
IntAct (EBI)P60323
BioGRIDNANOS3
STRING (EMBL)NANOS3
ZODIACNANOS3
Ontologies - Pathways
QuickGOP60323
Ontology : AmiGOP-body  RNA binding  mRNA binding  protein binding  nucleus  cytoplasm  regulation of translation  germ cell development  spermatogenesis  zinc ion binding  cytoplasmic stress granule  negative regulation of translation  negative regulation of translation  perinuclear region of cytoplasm  perinuclear region of cytoplasm  oogenesis  regulation of cell cycle  positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  negative regulation of apoptotic signaling pathway  
Ontology : EGO-EBIP-body  RNA binding  mRNA binding  protein binding  nucleus  cytoplasm  regulation of translation  germ cell development  spermatogenesis  zinc ion binding  cytoplasmic stress granule  negative regulation of translation  negative regulation of translation  perinuclear region of cytoplasm  perinuclear region of cytoplasm  oogenesis  regulation of cell cycle  positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  negative regulation of apoptotic signaling pathway  
NDEx NetworkNANOS3
Atlas of Cancer Signalling NetworkNANOS3
Wikipedia pathwaysNANOS3
Orthology - Evolution
OrthoDB342977
GeneTree (enSembl)ENSG00000187556
Phylogenetic Trees/Animal Genes : TreeFamNANOS3
Homologs : HomoloGeneNANOS3
Homology/Alignments : Family Browser (UCSC)NANOS3
Gene fusions - Rearrangements
Fusion : QuiverNANOS3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNANOS3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NANOS3
dbVarNANOS3
ClinVarNANOS3
MonarchNANOS3
1000_GenomesNANOS3 
Exome Variant ServerNANOS3
GNOMAD BrowserENSG00000187556
Varsome BrowserNANOS3
ACMGNANOS3 variants
VarityP60323
Genomic Variants (DGV)NANOS3 [DGVbeta]
DECIPHERNANOS3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNANOS3 
Mutations
ICGC Data PortalNANOS3 
TCGA Data PortalNANOS3 
Broad Tumor PortalNANOS3
OASIS PortalNANOS3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNANOS3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNANOS3
Mutations and Diseases : HGMDNANOS3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNANOS3
DgiDB (Drug Gene Interaction Database)NANOS3
DoCM (Curated mutations)NANOS3
CIViC (Clinical Interpretations of Variants in Cancer)NANOS3
Cancer3DNANOS3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608229   
Orphanet
DisGeNETNANOS3
MedgenNANOS3
Genetic Testing Registry NANOS3
NextProtP60323 [Medical]
GENETestsNANOS3
Target ValidationNANOS3
Huge Navigator NANOS3 [HugePedia]
ClinGenNANOS3
Clinical trials, drugs, therapy
MyCancerGenomeNANOS3
Protein Interactions : CTDNANOS3
Pharm GKB GenePA134867615
PharosP60323
Clinical trialNANOS3
Miscellaneous
canSAR (ICR)NANOS3
HarmonizomeNANOS3
ARCHS4NANOS3
DataMed IndexNANOS3
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNANOS3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Jan 20 12:48:35 CET 2022

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