NANOS3 (nanos C2HC-type zinc finger 3)

2015-11-01  

Identity

HGNC
NANOS3
LOCATION
19p13.12
LOCUSID
342977
ALIAS
NANOS1L,NOS3,ZC2HC12C

Other Information

Locus ID:

NCBI: 342977
MIM: 608229
HGNC: 22048
Ensembl: ENSG00000187556

Variants:

dbSNP: 342977
ClinVar: 342977
TCGA: ENSG00000187556
COSMIC: NANOS3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000187556ENST00000339133P60323
ENSG00000187556ENST00000397555P60323

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
277687802016Over Expression of NANOS3 and DAZL in Human Embryonic Stem Cells.3
174181572007Mutation analysis of NANOS3 in 80 Chinese and 88 Caucasian women with premature ovarian failure.0
174181572007Mutation analysis of NANOS3 in 80 Chinese and 88 Caucasian women with premature ovarian failure.0
195656402009NANOS3 gene mutations in men with isolated sterility phenotype.0
214219982011NANOS3 function in human germ cell development.0
240916682013A NANOS3 mutation linked to protein degradation causes premature ovarian insufficiency.0
250541462014Homozygous inactivating mutation in NANOS3 in two sisters with primary ovarian insufficiency.0
259043642015The human NANOS3 gene contributes to lung tumour invasion by inducing epithelial-mesenchymal transition.0
280765122016Mutation analysis of NANOS3 in Brazilian women with primary ovarian failure.0

Citation

Dessen P

NANOS3 (nanos C2HC-type zinc finger 3)

Atlas Genet Cytogenet Oncol Haematol. 2015-11-01

Online version: http://atlasgeneticsoncology.org/gene/55514/nanos3