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NANS (N-acetylneuraminic acid synthase)

Identity

Other namesHEL-S-100
SAS
HGNC (Hugo) NANS
LocusID (NCBI) 54187
Location 9q22.33
Location_base_pair Starts at 100818959 and ends at 100845365 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NANS   19237
Cards
Entrez_Gene (NCBI)NANS  54187  N-acetylneuraminic acid synthase
GeneCards (Weizmann)NANS
Ensembl (Hinxton)ENSG00000095380 [Gene_View]  chr9:100818959-100845365 [Contig_View]  NANS [Vega]
ICGC DataPortalENSG00000095380
cBioPortalNANS
AceView (NCBI)NANS
Genatlas (Paris)NANS
WikiGenes54187
SOURCE (Princeton)NM_018946
Genomic and cartography
GoldenPath (UCSC)NANS  -  9q22.33   chr9:100818959-100845365 +  9q22.33   [Description]    (hg19-Feb_2009)
EnsemblNANS - 9q22.33 [CytoView]
Mapping of homologs : NCBINANS [Mapview]
OMIM605202   
Gene and transcription
Genbank (Entrez)AF161387 AF257466 AK001659 AK091184 AK316608
RefSeq transcript (Entrez)NM_018946
RefSeq genomic (Entrez)AC_000141 NC_000009 NC_018920 NT_008470 NW_001839236 NW_004929366
Consensus coding sequences : CCDS (NCBI)NANS
Cluster EST : UnigeneHs.665191 [ NCBI ]
CGAP (NCI)Hs.665191
Alternative Splicing : Fast-db (Paris)GSHG0030310
Alternative Splicing GalleryENSG00000095380
Gene ExpressionNANS [ NCBI-GEO ]     NANS [ SEEK ]   NANS [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NR45 (Uniprot)
NextProtQ9NR45  [Medical]
With graphics : InterProQ9NR45
Splice isoforms : SwissVarQ9NR45 (Swissvar)
Catalytic activity : Enzyme2.5.1.56 [ Enzyme-Expasy ]   2.5.1.562.5.1.56 [ IntEnz-EBI ]   2.5.1.56 [ BRENDA ]   2.5.1.56 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)AFP_LIKE (PS50844)   
Domains : Interpro (EBI)AFP_Neu5c_C [organisation]   Aldolase_TIM [organisation]   Antifreeze_III [organisation]   Neu5Ac_N [organisation]   SAF [organisation]  
Related proteins : CluSTrQ9NR45
Domain families : Pfam (Sanger)NeuB (PF03102)    SAF (PF08666)   
Domain families : Pfam (NCBI)pfam03102    pfam08666   
Domain families : Smart (EMBL)SAF (SM00858)  
DMDM Disease mutations54187
Blocks (Seattle)Q9NR45
PDB (SRS)1WVO   
PDB (PDBSum)1WVO   
PDB (IMB)1WVO   
PDB (RSDB)1WVO   
Human Protein AtlasENSG00000095380 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ9NR45
HPRD07285
IPIIPI00147874   IPI00514997   IPI00000567   IPI00514469   
Protein Interaction databases
DIP (DOE-UCLA)Q9NR45
IntAct (EBI)Q9NR45
FunCoupENSG00000095380
BioGRIDNANS
InParanoidQ9NR45
Interologous Interaction database Q9NR45
IntegromeDBNANS
STRING (EMBL)NANS
Ontologies - Pathways
Ontology : AmiGOcytoplasm  cytosol  N-acylneuraminate cytidylyltransferase activity  lipopolysaccharide biosynthetic process  N-acylneuraminate-9-phosphate synthase activity  N-acetylneuraminate synthase activity  extracellular vesicular exosome  
Ontology : EGO-EBIcytoplasm  cytosol  N-acylneuraminate cytidylyltransferase activity  lipopolysaccharide biosynthetic process  N-acylneuraminate-9-phosphate synthase activity  N-acetylneuraminate synthase activity  extracellular vesicular exosome  
Pathways : KEGGAmino sugar and nucleotide sugar metabolism   
Protein Interaction DatabaseNANS
Wikipedia pathwaysNANS
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)NANS
snp3D : Map Gene to Disease54187
SNP (GeneSNP Utah)NANS
SNP : HGBaseNANS
Genetic variants : HAPMAPNANS
Exome VariantNANS
1000_GenomesNANS 
ICGC programENSG00000095380 
Somatic Mutations in Cancer : COSMICNANS 
CONAN: Copy Number AnalysisNANS 
Mutations and Diseases : HGMDNANS
Mutations and Diseases : intOGenNANS
Genomic VariantsNANS  NANS [DGVbeta]
dbVarNANS
ClinVarNANS
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM605202   
MedgenNANS
GENETestsNANS
Disease Genetic AssociationNANS
Huge Navigator NANS [HugePedia]  NANS [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneNANS
Homology/Alignments : Family Browser (UCSC)NANS
Phylogenetic Trees/Animal Genes : TreeFamNANS
Chemical/Protein Interactions : CTD54187
Chemical/Pharm GKB GenePA134978885
Clinical trialNANS
Cancer Resource (Charite)ENSG00000095380
Other databases
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
CoreMineNANS
iHOPNANS
OncoSearchNANS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 19:05:57 CEST 2014

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