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NANS (N-acetylneuraminate synthase)

Identity

Other namesHEL-S-100
SAS
HGNC (Hugo) NANS
LocusID (NCBI) 54187
Atlas_Id 41493
Location 9q22.33  [Link to chromosome band 9q22]
Location_base_pair Starts at 100818959 and ends at 100845365 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
NANS (9q22.33) / LRRC41 (1p34.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NANS   19237
Cards
Entrez_Gene (NCBI)NANS  54187  N-acetylneuraminate synthase
AliasesHEL-S-100; SAS
GeneCards (Weizmann)NANS
Ensembl hg19 (Hinxton)ENSG00000095380 [Gene_View]  chr9:100818959-100845365 [Contig_View]  NANS [Vega]
Ensembl hg38 (Hinxton)ENSG00000095380 [Gene_View]  chr9:100818959-100845365 [Contig_View]  NANS [Vega]
ICGC DataPortalENSG00000095380
TCGA cBioPortalNANS
AceView (NCBI)NANS
Genatlas (Paris)NANS
WikiGenes54187
SOURCE (Princeton)NANS
Genomic and cartography
GoldenPath hg19 (UCSC)NANS  -     chr9:100818959-100845365 +  9q22.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NANS  -     9q22.33   [Description]    (hg38-Dec_2013)
EnsemblNANS - 9q22.33 [CytoView hg19]  NANS - 9q22.33 [CytoView hg38]
Mapping of homologs : NCBINANS [Mapview hg19]  NANS [Mapview hg38]
OMIM605202   
Gene and transcription
Genbank (Entrez)AF161387 AF257466 AK001659 AK091184 AK316608
RefSeq transcript (Entrez)NM_018946
RefSeq genomic (Entrez)NC_000009 NC_018920 NT_008470 NW_004929366
Consensus coding sequences : CCDS (NCBI)NANS
Cluster EST : UnigeneHs.665191 [ NCBI ]
CGAP (NCI)Hs.665191
Alternative Splicing GalleryENSG00000095380
Gene ExpressionNANS [ NCBI-GEO ]   NANS [ EBI - ARRAY_EXPRESS ]   NANS [ SEEK ]   NANS [ MEM ]
Gene Expression Viewer (FireBrowse)NANS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54187
GTEX Portal (Tissue expression)NANS
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NR45 (Uniprot)
NextProtQ9NR45  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NR45
Splice isoforms : SwissVarQ9NR45 (Swissvar)
Catalytic activity : Enzyme2.5.1.56 [ Enzyme-Expasy ]   2.5.1.562.5.1.56 [ IntEnz-EBI ]   2.5.1.56 [ BRENDA ]   2.5.1.56 [ KEGG ]   
PhosPhoSitePlusQ9NR45
Domaine pattern : Prosite (Expaxy)AFP_LIKE (PS50844)   
Domains : Interpro (EBI)AFP_Neu5c_C    Aldolase_TIM    Antifreeze_III    Neu5Ac_N    SAF   
Domain families : Pfam (Sanger)NeuB (PF03102)   
Domain families : Pfam (NCBI)pfam03102   
Domain families : Smart (EMBL)SAF (SM00858)  
DMDM Disease mutations54187
Blocks (Seattle)NANS
PDB (SRS)1WVO   
PDB (PDBSum)1WVO   
PDB (IMB)1WVO   
PDB (RSDB)1WVO   
Structural Biology KnowledgeBase1WVO   
SCOP (Structural Classification of Proteins)1WVO   
CATH (Classification of proteins structures)1WVO   
SuperfamilyQ9NR45
Human Protein AtlasENSG00000095380
Peptide AtlasQ9NR45
HPRD07285
IPIIPI00147874   IPI00514997   IPI00000567   IPI00514469   
Protein Interaction databases
DIP (DOE-UCLA)Q9NR45
IntAct (EBI)Q9NR45
FunCoupENSG00000095380
BioGRIDNANS
STRING (EMBL)NANS
ZODIACNANS
Ontologies - Pathways
QuickGOQ9NR45
Ontology : AmiGOcytoplasm  cytosol  N-acylneuraminate cytidylyltransferase activity  lipopolysaccharide biosynthetic process  N-acylneuraminate-9-phosphate synthase activity  N-acetylneuraminate synthase activity  extracellular exosome  
Ontology : EGO-EBIcytoplasm  cytosol  N-acylneuraminate cytidylyltransferase activity  lipopolysaccharide biosynthetic process  N-acylneuraminate-9-phosphate synthase activity  N-acetylneuraminate synthase activity  extracellular exosome  
Pathways : KEGGAmino sugar and nucleotide sugar metabolism   
NDEx NetworkNANS
Atlas of Cancer Signalling NetworkNANS
Wikipedia pathwaysNANS
Orthology - Evolution
OrthoDB54187
GeneTree (enSembl)ENSG00000095380
Phylogenetic Trees/Animal Genes : TreeFamNANS
Homologs : HomoloGeneNANS
Homology/Alignments : Family Browser (UCSC)NANS
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerNANS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NANS
dbVarNANS
ClinVarNANS
1000_GenomesNANS 
Exome Variant ServerNANS
ExAC (Exome Aggregation Consortium)NANS (select the gene name)
Genetic variants : HAPMAP54187
Genomic Variants (DGV)NANS [DGVbeta]
Mutations
ICGC Data PortalNANS 
TCGA Data PortalNANS 
Broad Tumor PortalNANS
OASIS PortalNANS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNANS 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NANS
DgiDB (Drug Gene Interaction Database)NANS
DoCM (Curated mutations)NANS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NANS (select a term)
intoGenNANS
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)9:100818959-100845365  ENSG00000095380
CONAN: Copy Number AnalysisNANS 
Mutations and Diseases : HGMDNANS
OMIM605202   
MedgenNANS
Genetic Testing Registry NANS
NextProtQ9NR45 [Medical]
TSGene54187
GENETestsNANS
Huge Navigator NANS [HugePedia]
snp3D : Map Gene to Disease54187
BioCentury BCIQNANS
ClinGenNANS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54187
Chemical/Pharm GKB GenePA134978885
Clinical trialNANS
Miscellaneous
canSAR (ICR)NANS (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNANS
EVEXNANS
GoPubMedNANS
iHOPNANS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 19 19:03:55 CEST 2016

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