Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome

Donate (in Euros)

Donate (in US Dollars)


NANS (N-acetylneuraminic acid synthase)

Identity

Other namesHEL-S-100
SAS
HGNC (Hugo) NANS
LocusID (NCBI) 54187
Location 9q22.33
Location_base_pair Starts at 100818959 and ends at 100845365 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NANS   19237
Cards
Entrez_Gene (NCBI)NANS  54187  N-acetylneuraminic acid synthase
GeneCards (Weizmann)NANS
Ensembl hg19 (Hinxton)ENSG00000095380 [Gene_View]  chr9:100818959-100845365 [Contig_View]  NANS [Vega]
Ensembl hg38 (Hinxton)ENSG00000095380 [Gene_View]  chr9:100818959-100845365 [Contig_View]  NANS [Vega]
ICGC DataPortalENSG00000095380
cBioPortalNANS
AceView (NCBI)NANS
Genatlas (Paris)NANS
WikiGenes54187
SOURCE (Princeton)NANS
Genomic and cartography
GoldenPath hg19 (UCSC)NANS  -     chr9:100818959-100845365 +  9q22.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NANS  -     9q22.33   [Description]    (hg38-Dec_2013)
EnsemblNANS - 9q22.33 [CytoView hg19]  NANS - 9q22.33 [CytoView hg38]
Mapping of homologs : NCBINANS [Mapview hg19]  NANS [Mapview hg38]
OMIM605202   
Gene and transcription
Genbank (Entrez)AF161387 AF257466 AK001659 AK091184 AK316608
RefSeq transcript (Entrez)NM_018946
RefSeq genomic (Entrez)AC_000141 NC_000009 NC_018920 NT_008470 NW_001839236 NW_004929366
Consensus coding sequences : CCDS (NCBI)NANS
Cluster EST : UnigeneHs.665191 [ NCBI ]
CGAP (NCI)Hs.665191
Alternative Splicing : Fast-db (Paris)GSHG0030310
Alternative Splicing GalleryENSG00000095380
Gene ExpressionNANS [ NCBI-GEO ]     NANS [ SEEK ]   NANS [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NR45 (Uniprot)
NextProtQ9NR45  [Medical]
With graphics : InterProQ9NR45
Splice isoforms : SwissVarQ9NR45 (Swissvar)
Catalytic activity : Enzyme2.5.1.56 [ Enzyme-Expasy ]   2.5.1.562.5.1.56 [ IntEnz-EBI ]   2.5.1.56 [ BRENDA ]   2.5.1.56 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)AFP_LIKE (PS50844)   
Domains : Interpro (EBI)AFP_Neu5c_C    Aldolase_TIM    Antifreeze_III    Neu5Ac_N    SAF   
Related proteins : CluSTrQ9NR45
Domain families : Pfam (Sanger)NeuB (PF03102)    SAF (PF08666)   
Domain families : Pfam (NCBI)pfam03102    pfam08666   
Domain families : Smart (EMBL)SAF (SM00858)  
DMDM Disease mutations54187
Blocks (Seattle)Q9NR45
PDB (SRS)1WVO   
PDB (PDBSum)1WVO   
PDB (IMB)1WVO   
PDB (RSDB)1WVO   
Human Protein AtlasENSG00000095380
Peptide AtlasQ9NR45
HPRD07285
IPIIPI00147874   IPI00514997   IPI00000567   IPI00514469   
Protein Interaction databases
DIP (DOE-UCLA)Q9NR45
IntAct (EBI)Q9NR45
FunCoupENSG00000095380
BioGRIDNANS
IntegromeDBNANS
STRING (EMBL)NANS
Ontologies - Pathways
QuickGOQ9NR45
Ontology : AmiGOcytoplasm  cytosol  N-acylneuraminate cytidylyltransferase activity  lipopolysaccharide biosynthetic process  N-acylneuraminate-9-phosphate synthase activity  N-acetylneuraminate synthase activity  extracellular vesicular exosome  
Ontology : EGO-EBIcytoplasm  cytosol  N-acylneuraminate cytidylyltransferase activity  lipopolysaccharide biosynthetic process  N-acylneuraminate-9-phosphate synthase activity  N-acetylneuraminate synthase activity  extracellular vesicular exosome  
Pathways : KEGGAmino sugar and nucleotide sugar metabolism   
Protein Interaction DatabaseNANS
DoCM (Curated mutations)NANS
Wikipedia pathwaysNANS
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerNANS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NANS
dbVarNANS
ClinVarNANS
1000_GenomesNANS 
Exome Variant ServerNANS
SNP (GeneSNP Utah)NANS
SNP : HGBaseNANS
Genetic variants : HAPMAPNANS
Genomic Variants (DGV)NANS [DGVbeta]
Mutations
ICGC Data PortalENSG00000095380 
Somatic Mutations in Cancer : COSMICNANS 
CONAN: Copy Number AnalysisNANS 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)9:100818959-100845365
Mutations and Diseases : HGMDNANS
OMIM605202   
MedgenNANS
NextProtQ9NR45 [Medical]
GENETestsNANS
Disease Genetic AssociationNANS
Huge Navigator NANS [HugePedia]  NANS [HugeCancerGEM]
snp3D : Map Gene to Disease54187
DGIdb (Drug Gene Interaction db)NANS
General knowledge
Homologs : HomoloGeneNANS
Homology/Alignments : Family Browser (UCSC)NANS
Phylogenetic Trees/Animal Genes : TreeFamNANS
Chemical/Protein Interactions : CTD54187
Chemical/Pharm GKB GenePA134978885
Clinical trialNANS
Cancer Resource (Charite)ENSG00000095380
Other databases
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
CoreMineNANS
GoPubMedNANS
iHOPNANS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2014Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Feb 14 17:36:56 CET 2015

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.