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NAP1L1 (nucleosome assembly protein 1 like 1)

Identity

Alias (NCBI)NAP1
NAP1L
NRP
HGNC (Hugo) NAP1L1
HGNC Alias symbNRP
NAP1
NAP1L
MGC8688
MGC23410
HGNC Previous namenucleosome assembly protein 1-like 1
LocusID (NCBI) 4673
Atlas_Id 52770
Location 12q21.2  [Link to chromosome band 12q21]
Location_base_pair Starts at 76044745 and ends at 76084685 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DNAJB2 (2q35) / NAP1L1 (12q21.2)EXOC7 (17q25.1) / NAP1L1 (12q21.2)LGMN (14q32.12) / NAP1L1 (12q21.2)
NAP1L1 (12q21.2) / LDHAL6A (11p15.1)NAP1L1 (12q21.2) / MLLT10 (10p12.31)NAP1L1 (12q21.2) / NAP1L1 (12q21.2)
NAP1L1 (12q21.2) / STK38L (12p11.23)NAP1L1 (12q21.2) / WHSC1 (4p16.3)NAP1L1 (12q21.2) / WNT7A (3p25.1)
NAP1L1 (12q21.2) / ZNF644 (1p22.2)NCL (2q37.1) / NAP1L1 (12q21.2)PATJ (1p31.3) / NAP1L1 (12q21.2)
UBAC1 (9q34.3) / NAP1L1 (12q21.2)NAP1L1 12q21.2 / STK38L 12p11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(10;12)(p12;q21) NAP1L1/MLLT10


External links

 

Nomenclature
HGNC (Hugo)NAP1L1   7637
Cards
Entrez_Gene (NCBI)NAP1L1    nucleosome assembly protein 1 like 1
AliasesNAP1; NAP1L; NRP
GeneCards (Weizmann)NAP1L1
Ensembl hg19 (Hinxton)ENSG00000187109 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187109 [Gene_View]  ENSG00000187109 [Sequence]  chr12:76044745-76084685 [Contig_View]  NAP1L1 [Vega]
ICGC DataPortalENSG00000187109
TCGA cBioPortalNAP1L1
AceView (NCBI)NAP1L1
Genatlas (Paris)NAP1L1
SOURCE (Princeton)NAP1L1
Genetics Home Reference (NIH)NAP1L1
Genomic and cartography
GoldenPath hg38 (UCSC)NAP1L1  -     chr12:76044745-76084685 -  12q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NAP1L1  -     12q21.2   [Description]    (hg19-Feb_2009)
GoldenPathNAP1L1 - 12q21.2 [CytoView hg19]  NAP1L1 - 12q21.2 [CytoView hg38]
ImmunoBaseENSG00000187109
Genome Data Viewer NCBINAP1L1 [Mapview hg19]  
OMIM164060   
Gene and transcription
Genbank (Entrez)AA057019 AF086080 AF088017 AF300335 AK021751
RefSeq transcript (Entrez)NM_001307924 NM_001330231 NM_001330232 NM_004537 NM_139207
Consensus coding sequences : CCDS (NCBI)NAP1L1
Gene ExpressionNAP1L1 [ NCBI-GEO ]   NAP1L1 [ EBI - ARRAY_EXPRESS ]   NAP1L1 [ SEEK ]   NAP1L1 [ MEM ]
Gene Expression Viewer (FireBrowse)NAP1L1 [ Firebrowse - Broad ]
GenevisibleExpression of NAP1L1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4673
GTEX Portal (Tissue expression)NAP1L1
Human Protein AtlasENSG00000187109-NAP1L1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55209   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55209  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55209
PhosPhoSitePlusP55209
Domains : Interpro (EBI)NAP-like_sf    NAP_family   
Domain families : Pfam (Sanger)NAP (PF00956)   
Domain families : Pfam (NCBI)pfam00956   
Conserved Domain (NCBI)NAP1L1
SuperfamilyP55209
AlphaFold pdb e-kbP55209   
Human Protein Atlas [tissue]ENSG00000187109-NAP1L1 [tissue]
HPRD01248
Protein Interaction databases
DIP (DOE-UCLA)P55209
IntAct (EBI)P55209
BioGRIDNAP1L1
STRING (EMBL)NAP1L1
ZODIACNAP1L1
Ontologies - Pathways
QuickGOP55209
Ontology : AmiGOchromatin  chromatin binding  RNA binding  protein binding  nucleus  nucleus  cytoplasm  DNA replication  nucleosome assembly  positive regulation of cell population proliferation  membrane  histone binding  melanosome  positive regulation of neurogenesis  positive regulation of neural precursor cell proliferation  
Ontology : EGO-EBIchromatin  chromatin binding  RNA binding  protein binding  nucleus  nucleus  cytoplasm  DNA replication  nucleosome assembly  positive regulation of cell population proliferation  membrane  histone binding  melanosome  positive regulation of neurogenesis  positive regulation of neural precursor cell proliferation  
NDEx NetworkNAP1L1
Atlas of Cancer Signalling NetworkNAP1L1
Wikipedia pathwaysNAP1L1
Orthology - Evolution
OrthoDB4673
GeneTree (enSembl)ENSG00000187109
Phylogenetic Trees/Animal Genes : TreeFamNAP1L1
Homologs : HomoloGeneNAP1L1
Homology/Alignments : Family Browser (UCSC)NAP1L1
Gene fusions - Rearrangements
Fusion : MitelmanLGMN/NAP1L1 [14q32.12/12q21.2]  
Fusion : MitelmanNAP1L1/MLLT10 [12q21.2/10p12.31]  
Fusion : MitelmanNAP1L1/STK38L [12q21.2/12p11.23]  
Fusion : QuiverNAP1L1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNAP1L1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NAP1L1
dbVarNAP1L1
ClinVarNAP1L1
MonarchNAP1L1
1000_GenomesNAP1L1 
Exome Variant ServerNAP1L1
GNOMAD BrowserENSG00000187109
Varsome BrowserNAP1L1
ACMGNAP1L1 variants
VarityP55209
Genomic Variants (DGV)NAP1L1 [DGVbeta]
DECIPHERNAP1L1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNAP1L1 
Mutations
ICGC Data PortalNAP1L1 
TCGA Data PortalNAP1L1 
Broad Tumor PortalNAP1L1
OASIS PortalNAP1L1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNAP1L1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNAP1L1
Mutations and Diseases : HGMDNAP1L1
intOGen PortalNAP1L1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNAP1L1
DgiDB (Drug Gene Interaction Database)NAP1L1
DoCM (Curated mutations)NAP1L1
CIViC (Clinical Interpretations of Variants in Cancer)NAP1L1
Cancer3DNAP1L1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM164060   
Orphanet
DisGeNETNAP1L1
MedgenNAP1L1
Genetic Testing Registry NAP1L1
NextProtP55209 [Medical]
GENETestsNAP1L1
Target ValidationNAP1L1
Huge Navigator NAP1L1 [HugePedia]
ClinGenNAP1L1
Clinical trials, drugs, therapy
MyCancerGenomeNAP1L1
Protein Interactions : CTDNAP1L1
Pharm GKB GenePA31439
PharosP55209
Clinical trialNAP1L1
Miscellaneous
canSAR (ICR)NAP1L1
HarmonizomeNAP1L1
DataMed IndexNAP1L1
Probes
Litterature
PubMed169 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNAP1L1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:22:02 CEST 2021

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