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NAPRT (nicotinate phosphoribosyltransferase)

Identity

Alias (NCBI)NAPRT1
PP3856
HGNC (Hugo) NAPRT
HGNC Alias symbPP3856
HGNC Previous nameNAPRT1
HGNC Previous namenicotinate phosphoribosyltransferase domain containing 1
LocusID (NCBI) 93100
Atlas_Id 54027
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 143574785 and ends at 143578330 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LCN2 (9q34.11) / NAPRT (8q24.3)NAPRT (8q24.3) / NAPRT (8q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NAPRT   30450
Cards
Entrez_Gene (NCBI)NAPRT    nicotinate phosphoribosyltransferase
AliasesNAPRT1; PP3856
GeneCards (Weizmann)NAPRT
Ensembl hg19 (Hinxton)ENSG00000147813 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147813 [Gene_View]  ENSG00000147813 [Sequence]  chr8:143574785-143578330 [Contig_View]  NAPRT [Vega]
ICGC DataPortalENSG00000147813
TCGA cBioPortalNAPRT
AceView (NCBI)NAPRT
Genatlas (Paris)NAPRT
SOURCE (Princeton)NAPRT
Genetics Home Reference (NIH)NAPRT
Genomic and cartography
GoldenPath hg38 (UCSC)NAPRT  -     chr8:143574785-143578330 -  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NAPRT  -     8q24.3   [Description]    (hg19-Feb_2009)
GoldenPathNAPRT - 8q24.3 [CytoView hg19]  NAPRT - 8q24.3 [CytoView hg38]
ImmunoBaseENSG00000147813
genome Data Viewer NCBINAPRT [Mapview hg19]  
OMIM611552   
Gene and transcription
Genbank (Entrez)AB242230 AF258565 AK097002 AY214325 AY214326
RefSeq transcript (Entrez)NM_001286829 NM_001363145 NM_001363146 NM_145201
RefSeq genomic (Entrez)NC_000008 NT_187571
Consensus coding sequences : CCDS (NCBI)NAPRT
Alternative Splicing GalleryENSG00000147813
Gene ExpressionNAPRT [ NCBI-GEO ]   NAPRT [ EBI - ARRAY_EXPRESS ]   NAPRT [ SEEK ]   NAPRT [ MEM ]
Gene Expression Viewer (FireBrowse)NAPRT [ Firebrowse - Broad ]
GenevisibleExpression of NAPRT in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)93100
GTEX Portal (Tissue expression)NAPRT
Human Protein AtlasENSG00000147813-NAPRT [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6XQN6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6XQN6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6XQN6
Splice isoforms : SwissVarQ6XQN6
PhosPhoSitePlusQ6XQN6
Domains : Interpro (EBI)Aldolase_TIM    NAPRTase_C    NAPRTase_N    Nic_PRibTrfase-Fam    Nic_PRibTrfase_pncB    Nicotinate_pribotase-like_C   
Domain families : Pfam (Sanger)NAPRTase_C (PF17956)    NAPRTase_N (PF17767)   
Domain families : Pfam (NCBI)pfam17956    pfam17767   
Conserved Domain (NCBI)NAPRT
Blocks (Seattle)NAPRT
PDB (RSDB)4YUB   
PDB Europe4YUB   
PDB (PDBSum)4YUB   
PDB (IMB)4YUB   
Structural Biology KnowledgeBase4YUB   
SCOP (Structural Classification of Proteins)4YUB   
CATH (Classification of proteins structures)4YUB   
SuperfamilyQ6XQN6
Human Protein Atlas [tissue]ENSG00000147813-NAPRT [tissue]
Peptide AtlasQ6XQN6
HPRD15161
IPIIPI00465085   IPI00879716   IPI00880164   IPI00952992   IPI00412498   IPI00978154   IPI00978857   
Protein Interaction databases
DIP (DOE-UCLA)Q6XQN6
IntAct (EBI)Q6XQN6
BioGRIDNAPRT
STRING (EMBL)NAPRT
ZODIACNAPRT
Ontologies - Pathways
QuickGOQ6XQN6
Ontology : AmiGOnicotinate-nucleotide diphosphorylase (carboxylating) activity  nicotinate phosphoribosyltransferase activity  nicotinate phosphoribosyltransferase activity  protein binding  extracellular region  cytosol  cytosol  cytosol  response to oxidative stress  NAD salvage  NAD biosynthesis via nicotinamide riboside salvage pathway  azurophil granule lumen  neutrophil degranulation  metal ion binding  extracellular exosome  
Ontology : EGO-EBInicotinate-nucleotide diphosphorylase (carboxylating) activity  nicotinate phosphoribosyltransferase activity  nicotinate phosphoribosyltransferase activity  protein binding  extracellular region  cytosol  cytosol  cytosol  response to oxidative stress  NAD salvage  NAD biosynthesis via nicotinamide riboside salvage pathway  azurophil granule lumen  neutrophil degranulation  metal ion binding  extracellular exosome  
NDEx NetworkNAPRT
Atlas of Cancer Signalling NetworkNAPRT
Wikipedia pathwaysNAPRT
Orthology - Evolution
OrthoDB93100
GeneTree (enSembl)ENSG00000147813
Phylogenetic Trees/Animal Genes : TreeFamNAPRT
HOGENOMQ6XQN6
Homologs : HomoloGeneNAPRT
Homology/Alignments : Family Browser (UCSC)NAPRT
Gene fusions - Rearrangements
Fusion : QuiverNAPRT
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNAPRT [hg38]
dbVarNAPRT
ClinVarNAPRT
MonarchNAPRT
1000_GenomesNAPRT 
Exome Variant ServerNAPRT
GNOMAD BrowserENSG00000147813
Varsome BrowserNAPRT
Genomic Variants (DGV)NAPRT [DGVbeta]
DECIPHERNAPRT [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNAPRT 
Mutations
ICGC Data PortalNAPRT 
TCGA Data PortalNAPRT 
Broad Tumor PortalNAPRT
OASIS PortalNAPRT [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNAPRT  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNAPRT
Mutations and Diseases : HGMDNAPRT
BioMutasearch NAPRT
DgiDB (Drug Gene Interaction Database)NAPRT
DoCM (Curated mutations)NAPRT (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NAPRT (select a term)
intoGenNAPRT
Cancer3DNAPRT(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611552   
Orphanet
DisGeNETNAPRT
MedgenNAPRT
Genetic Testing Registry NAPRT
NextProtQ6XQN6 [Medical]
GENETestsNAPRT
Target ValidationNAPRT
Huge Navigator NAPRT [HugePedia]
ClinGenNAPRT
Clinical trials, drugs, therapy
MyCancerGenomeNAPRT
Protein Interactions : CTD
Pharm GKB GenePA142671293
PharosQ6XQN6
Clinical trialNAPRT
Miscellaneous
canSAR (ICR)NAPRT (select the gene name)
HarmonizomeNAPRT
DataMed IndexNAPRT
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNAPRT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 25 19:35:43 CET 2021
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