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NAPSA (napsin A aspartic peptidase)

Identity

Alias_symbol (synonym)NAP1
NAPA
Kdap
KAP
Other aliasSNAPA
HGNC (Hugo) NAPSA
LocusID (NCBI) 9476
Atlas_Id 45653
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 50358472 and ends at 50365830 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ALDH1A3 (15q26.3) / NAPSA (19q13.33)NAPSB (19q13.33) / NAPSA (19q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NAPSA   13395
Cards
Entrez_Gene (NCBI)NAPSA  9476  napsin A aspartic peptidase
AliasesKAP; Kdap; NAP1; NAPA; 
SNAPA
GeneCards (Weizmann)NAPSA
Ensembl hg19 (Hinxton)ENSG00000131400 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131400 [Gene_View]  chr19:50358472-50365830 [Contig_View]  NAPSA [Vega]
ICGC DataPortalENSG00000131400
TCGA cBioPortalNAPSA
AceView (NCBI)NAPSA
Genatlas (Paris)NAPSA
WikiGenes9476
SOURCE (Princeton)NAPSA
Genetics Home Reference (NIH)NAPSA
Genomic and cartography
GoldenPath hg38 (UCSC)NAPSA  -     chr19:50358472-50365830 -  19q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NAPSA  -     19q13.33   [Description]    (hg19-Feb_2009)
EnsemblNAPSA - 19q13.33 [CytoView hg19]  NAPSA - 19q13.33 [CytoView hg38]
Mapping of homologs : NCBINAPSA [Mapview hg19]  NAPSA [Mapview hg38]
OMIM605631   
Gene and transcription
Genbank (Entrez)AF090386 AF098484 AF200345 AK055569 AK308013
RefSeq transcript (Entrez)NM_004851
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NAPSA
Cluster EST : UnigeneHs.512843 [ NCBI ]
CGAP (NCI)Hs.512843
Alternative Splicing GalleryENSG00000131400
Gene ExpressionNAPSA [ NCBI-GEO ]   NAPSA [ EBI - ARRAY_EXPRESS ]   NAPSA [ SEEK ]   NAPSA [ MEM ]
Gene Expression Viewer (FireBrowse)NAPSA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9476
GTEX Portal (Tissue expression)NAPSA
Protein : pattern, domain, 3D structure
UniProt/SwissProtO96009   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO96009  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO96009
Splice isoforms : SwissVarO96009
Catalytic activity : Enzyme3.4.23.- [ Enzyme-Expasy ]   3.4.23.-3.4.23.- [ IntEnz-EBI ]   3.4.23.- [ BRENDA ]   3.4.23.- [ KEGG ]   
PhosPhoSitePlusO96009
Domaine pattern : Prosite (Expaxy)ASP_PROTEASE (PS00141)    PEPTIDASE_A1 (PS51767)   
Domains : Interpro (EBI)Aspartic_peptidase_A1    Aspartic_peptidase_AS    PEPTIDASE_A1    Peptidase_aspartic_dom   
Domain families : Pfam (Sanger)Asp (PF00026)   
Domain families : Pfam (NCBI)pfam00026   
Conserved Domain (NCBI)NAPSA
DMDM Disease mutations9476
Blocks (Seattle)NAPSA
SuperfamilyO96009
Human Protein AtlasENSG00000131400
Peptide AtlasO96009
HPRD07064
IPIIPI00014055   
Protein Interaction databases
DIP (DOE-UCLA)O96009
IntAct (EBI)O96009
FunCoupENSG00000131400
BioGRIDNAPSA
STRING (EMBL)NAPSA
ZODIACNAPSA
Ontologies - Pathways
QuickGOO96009
Ontology : AmiGOendopeptidase activity  aspartic-type endopeptidase activity  aspartic-type endopeptidase activity  extracellular space  lysosome  proteolysis  autophagy  peptidase activity  peptidase activity  protein catabolic process  membrane protein proteolysis  surfactant homeostasis  cellular protein metabolic process  extracellular exosome  alveolar lamellar body  multivesicular body lumen  
Ontology : EGO-EBIendopeptidase activity  aspartic-type endopeptidase activity  aspartic-type endopeptidase activity  extracellular space  lysosome  proteolysis  autophagy  peptidase activity  peptidase activity  protein catabolic process  membrane protein proteolysis  surfactant homeostasis  cellular protein metabolic process  extracellular exosome  alveolar lamellar body  multivesicular body lumen  
Pathways : KEGGLysosome   
NDEx NetworkNAPSA
Atlas of Cancer Signalling NetworkNAPSA
Wikipedia pathwaysNAPSA
Orthology - Evolution
OrthoDB9476
GeneTree (enSembl)ENSG00000131400
Phylogenetic Trees/Animal Genes : TreeFamNAPSA
HOVERGENO96009
HOGENOMO96009
Homologs : HomoloGeneNAPSA
Homology/Alignments : Family Browser (UCSC)NAPSA
Gene fusions - Rearrangements
Fusion Cancer (Beijing)ALDH1A3 [15q26.3]  -  NAPSA [19q13.33]  [FUSC003526]
Fusion Cancer (Beijing)NAPSB [19q13.33]  -  NAPSA [19q13.33]  [FUSC002580]  [FUSC002580]  [FUSC002580]  [FUSC002580]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNAPSA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NAPSA
dbVarNAPSA
ClinVarNAPSA
1000_GenomesNAPSA 
Exome Variant ServerNAPSA
ExAC (Exome Aggregation Consortium)NAPSA (select the gene name)
Genetic variants : HAPMAP9476
Genomic Variants (DGV)NAPSA [DGVbeta]
DECIPHERNAPSA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNAPSA 
Mutations
ICGC Data PortalNAPSA 
TCGA Data PortalNAPSA 
Broad Tumor PortalNAPSA
OASIS PortalNAPSA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNAPSA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNAPSA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NAPSA
DgiDB (Drug Gene Interaction Database)NAPSA
DoCM (Curated mutations)NAPSA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NAPSA (select a term)
intoGenNAPSA
Cancer3DNAPSA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605631   
Orphanet
MedgenNAPSA
Genetic Testing Registry NAPSA
NextProtO96009 [Medical]
TSGene9476
GENETestsNAPSA
Target ValidationNAPSA
Huge Navigator NAPSA [HugePedia]
snp3D : Map Gene to Disease9476
BioCentury BCIQNAPSA
ClinGenNAPSA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9476
Chemical/Pharm GKB GenePA134891814
Clinical trialNAPSA
Miscellaneous
canSAR (ICR)NAPSA (select the gene name)
Probes
Litterature
PubMed56 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNAPSA
EVEXNAPSA
GoPubMedNAPSA
iHOPNAPSA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:21:24 CEST 2017

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