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NARS (asparaginyl-tRNA synthetase)

Identity

Alias_symbol (synonym)NARS1
Other aliasASNRS
HGNC (Hugo) NARS
LocusID (NCBI) 4677
Atlas_Id 70696
Location 18q21.31  [Link to chromosome band 18q21]
Location_base_pair Starts at 55267894 and ends at 55289177 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
BRINP3 (1q31.1) / NARS (18q21.31)CHD3 (17p13.1) / NARS (18q21.31)FKBP4 (12p13.33) / NARS (18q21.31)
NARS (18q21.31) / NARS (18q21.31)NARS (18q21.31) / PVT1 (8q24.21)ZNF14 (19p13.11) / NARS (18q21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NARS   7643
Cards
Entrez_Gene (NCBI)NARS  4677  asparaginyl-tRNA synthetase
AliasesASNRS; NARS1
GeneCards (Weizmann)NARS
Ensembl hg19 (Hinxton)ENSG00000134440 [Gene_View]  chr18:55267894-55289177 [Contig_View]  NARS [Vega]
Ensembl hg38 (Hinxton)ENSG00000134440 [Gene_View]  chr18:55267894-55289177 [Contig_View]  NARS [Vega]
ICGC DataPortalENSG00000134440
TCGA cBioPortalNARS
AceView (NCBI)NARS
Genatlas (Paris)NARS
WikiGenes4677
SOURCE (Princeton)NARS
Genetics Home Reference (NIH)NARS
Genomic and cartography
GoldenPath hg19 (UCSC)NARS  -     chr18:55267894-55289177 -  18q21.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NARS  -     18q21.31   [Description]    (hg38-Dec_2013)
EnsemblNARS - 18q21.31 [CytoView hg19]  NARS - 18q21.31 [CytoView hg38]
Mapping of homologs : NCBINARS [Mapview hg19]  NARS [Mapview hg38]
OMIM108410   
Gene and transcription
Genbank (Entrez)AJ000334 AK129897 AK222835 AK293985 AK294364
RefSeq transcript (Entrez)NM_004539
RefSeq genomic (Entrez)NC_000018 NC_018929 NT_010966 NW_004929411
Consensus coding sequences : CCDS (NCBI)NARS
Cluster EST : UnigeneHs.465224 [ NCBI ]
CGAP (NCI)Hs.465224
Alternative Splicing GalleryENSG00000134440
Gene ExpressionNARS [ NCBI-GEO ]   NARS [ EBI - ARRAY_EXPRESS ]   NARS [ SEEK ]   NARS [ MEM ]
Gene Expression Viewer (FireBrowse)NARS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4677
GTEX Portal (Tissue expression)NARS
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43776   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43776  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43776
Splice isoforms : SwissVarO43776
Catalytic activity : Enzyme6.1.1.22 [ Enzyme-Expasy ]   6.1.1.226.1.1.22 [ IntEnz-EBI ]   6.1.1.22 [ BRENDA ]   6.1.1.22 [ KEGG ]   
PhosPhoSitePlusO43776
Domaine pattern : Prosite (Expaxy)AA_TRNA_LIGASE_II (PS50862)   
Domains : Interpro (EBI)aa-tRNA-synt_II    aa-tRNA-synt_II-like    aa-tRNA-synth_II    Asn-tRNA-ligase    Asp/Asn-tRNA-synth_IIb    NA-bd_OB-fold    NA-bd_OB_tRNA   
Domain families : Pfam (Sanger)tRNA-synt_2 (PF00152)    tRNA_anti-codon (PF01336)   
Domain families : Pfam (NCBI)pfam00152    pfam01336   
Conserved Domain (NCBI)NARS
DMDM Disease mutations4677
Blocks (Seattle)NARS
SuperfamilyO43776
Human Protein AtlasENSG00000134440
Peptide AtlasO43776
HPRD00154
IPIIPI00306960   IPI00646656   IPI00643900   IPI00647678   
Protein Interaction databases
DIP (DOE-UCLA)O43776
IntAct (EBI)O43776
FunCoupENSG00000134440
BioGRIDNARS
STRING (EMBL)NARS
ZODIACNARS
Ontologies - Pathways
QuickGOO43776
Ontology : AmiGOnucleic acid binding  asparagine-tRNA ligase activity  ATP binding  cytoplasm  mitochondrion  cytosol  tRNA aminoacylation for protein translation  asparaginyl-tRNA aminoacylation  gene expression  extracellular exosome  
Ontology : EGO-EBInucleic acid binding  asparagine-tRNA ligase activity  ATP binding  cytoplasm  mitochondrion  cytosol  tRNA aminoacylation for protein translation  asparaginyl-tRNA aminoacylation  gene expression  extracellular exosome  
Pathways : KEGGAminoacyl-tRNA biosynthesis   
NDEx NetworkNARS
Atlas of Cancer Signalling NetworkNARS
Wikipedia pathwaysNARS
Orthology - Evolution
OrthoDB4677
GeneTree (enSembl)ENSG00000134440
Phylogenetic Trees/Animal Genes : TreeFamNARS
HOVERGENO43776
HOGENOMO43776
Homologs : HomoloGeneNARS
Homology/Alignments : Family Browser (UCSC)NARS
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNARS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NARS
dbVarNARS
ClinVarNARS
1000_GenomesNARS 
Exome Variant ServerNARS
ExAC (Exome Aggregation Consortium)NARS (select the gene name)
Genetic variants : HAPMAP4677
Genomic Variants (DGV)NARS [DGVbeta]
DECIPHER (Syndromes)18:55267894-55289177  ENSG00000134440
CONAN: Copy Number AnalysisNARS 
Mutations
ICGC Data PortalNARS 
TCGA Data PortalNARS 
Broad Tumor PortalNARS
OASIS PortalNARS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNARS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNARS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NARS
DgiDB (Drug Gene Interaction Database)NARS
DoCM (Curated mutations)NARS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NARS (select a term)
intoGenNARS
Cancer3DNARS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM108410   
Orphanet
MedgenNARS
Genetic Testing Registry NARS
NextProtO43776 [Medical]
TSGene4677
GENETestsNARS
Huge Navigator NARS [HugePedia]
snp3D : Map Gene to Disease4677
BioCentury BCIQNARS
ClinGenNARS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4677
Chemical/Pharm GKB GenePA31447
Clinical trialNARS
Miscellaneous
canSAR (ICR)NARS (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNARS
EVEXNARS
GoPubMedNARS
iHOPNARS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:34:32 CET 2017

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