NARS1 (asparaginyl-tRNA synthetase 1)

2017-08-01  

Identity

HGNC
NARS1
LOCATION
18q21.31
LOCUSID
4677
ALIAS
ASNRS,NARS,NEDMILEG,NEDMILG

Other Information

Locus ID:

NCBI: 4677
MIM: 108410
HGNC: 7643
Ensembl: ENSG00000134440

Variants:

dbSNP: 4677
ClinVar: 4677
TCGA: ENSG00000134440
COSMIC: NARS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134440ENST00000256854O43776
ENSG00000134440ENST00000540592O43776
ENSG00000134440ENST00000586807K7EJ19
ENSG00000134440ENST00000587194K7EIU7
ENSG00000134440ENST00000587675K7EMQ6
ENSG00000134440ENST00000588661K7EPK2
ENSG00000134440ENST00000590123K7ENF0
ENSG00000134440ENST00000591599K7EQ35

Pathways

PathwaySourceExternal ID
Aminoacyl-tRNA biosynthesisKEGGko00970
Aminoacyl-tRNA biosynthesisKEGGhsa00970
Aminoacyl-tRNA biosynthesis, eukaryotesKEGGhsa_M00359
Aminoacyl-tRNA biosynthesis, eukaryotesKEGGM00359
Gene ExpressionREACTOMER-HSA-74160
tRNA AminoacylationREACTOMER-HSA-379724
Cytosolic tRNA aminoacylationREACTOMER-HSA-379716

References

Pubmed IDYearTitleCitations
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
271614462016Identification and Characterization of Potential Biomarkers by Quantitative Tissue Proteomics of Primary Lung Adenocarcinoma.12
301719542018Unique N-terminal extension domain of human asparaginyl-tRNA synthetase elicits CCR3-mediated chemokine activity.4

Citation

Dessen P

NARS1 (asparaginyl-tRNA synthetase 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/56997/nars1