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NASP (nuclear autoantigenic sperm protein)

Identity

Alias_namesnuclear autoantigenic sperm protein (histone-binding)
Alias_symbol (synonym)FLB7527
FLJ31599
FLJ35510
MGC19722
MGC20372
MGC2297
DKFZp547F162
PRO1999
Other aliasHMDRA1
HGNC (Hugo) NASP
LocusID (NCBI) 4678
Atlas_Id 41496
Location 1p34.1  [Link to chromosome band 1p34]
Location_base_pair Starts at 45583988 and ends at 45618906 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BCL2L2-PABPN1 (14q11.2) / NASP (1p34.1)JUND (19p13.11) / NASP (1p34.1)MALAT1 (11q13.1) / NASP (1p34.1)
MAST2 (1p34.1) / NASP (1p34.1)NASP (1p34.1) / AC022182.1 ()NASP (1p34.1) / IGFBP5 (2q35)
NASP (1p34.1) / LUC7L3 (17q21.33)NASP (1p34.1) / NOP56 (20p13)NASP (1p34.1) / NPIPB7 (16q23.1)
NASP (1p34.1) / WIPF1 (2q31.1)NDUFB11 (Xp11.23) / NASP (1p34.1)SETD2 (3p21.31) / NASP (1p34.1)
SST (3q27.3) / NASP (1p34.1)MAST2 1p34.1 / NASP 1p34.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NASP   7644
Cards
Entrez_Gene (NCBI)NASP  4678  nuclear autoantigenic sperm protein
AliasesFLB7527; HMDRA1; PRO1999
GeneCards (Weizmann)NASP
Ensembl hg19 (Hinxton)ENSG00000132780 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000132780 [Gene_View]  chr1:45583988-45618906 [Contig_View]  NASP [Vega]
ICGC DataPortalENSG00000132780
TCGA cBioPortalNASP
AceView (NCBI)NASP
Genatlas (Paris)NASP
WikiGenes4678
SOURCE (Princeton)NASP
Genetics Home Reference (NIH)NASP
Genomic and cartography
GoldenPath hg38 (UCSC)NASP  -     chr1:45583988-45618906 +  1p34.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NASP  -     1p34.1   [Description]    (hg19-Feb_2009)
EnsemblNASP - 1p34.1 [CytoView hg19]  NASP - 1p34.1 [CytoView hg38]
Mapping of homologs : NCBINASP [Mapview hg19]  NASP [Mapview hg38]
OMIM603185   
Gene and transcription
Genbank (Entrez)AF035191 AK056161 AK092829 AK131249 AK222778
RefSeq transcript (Entrez)NM_001195193 NM_002482 NM_152298 NM_172164
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NASP
Cluster EST : UnigeneHs.319334 [ NCBI ]
CGAP (NCI)Hs.319334
Alternative Splicing GalleryENSG00000132780
Gene ExpressionNASP [ NCBI-GEO ]   NASP [ EBI - ARRAY_EXPRESS ]   NASP [ SEEK ]   NASP [ MEM ]
Gene Expression Viewer (FireBrowse)NASP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4678
GTEX Portal (Tissue expression)NASP
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49321   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49321  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49321
Splice isoforms : SwissVarP49321
PhosPhoSitePlusP49321
Domaine pattern : Prosite (Expaxy)TPR (PS50005)    TPR_REGION (PS50293)   
Domains : Interpro (EBI)Tetratricopeptide_SHNi-TPR_dom    TPR-contain_dom    TPR-like_helical_dom    TPR_repeat   
Domain families : Pfam (Sanger)SHNi-TPR (PF10516)   
Domain families : Pfam (NCBI)pfam10516   
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)NASP
DMDM Disease mutations4678
Blocks (Seattle)NASP
SuperfamilyP49321
Human Protein AtlasENSG00000132780
Peptide AtlasP49321
HPRD04423
IPIIPI00179953   IPI00219821   IPI00332499   IPI01015635   IPI01014799   IPI00977883   IPI00646459   IPI00514504   IPI00639912   IPI00976083   IPI00983764   IPI00977191   IPI00982556   IPI00977790   IPI00984344   IPI00983159   IPI00978413   
Protein Interaction databases
DIP (DOE-UCLA)P49321
IntAct (EBI)P49321
FunCoupENSG00000132780
BioGRIDNASP
STRING (EMBL)NASP
ZODIACNASP
Ontologies - Pathways
QuickGOP49321
Ontology : AmiGOnuclear chromatin  blastocyst development  protein binding  nucleus  nucleoplasm  cytoplasm  DNA replication  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  cell cycle  cell proliferation  male gonad development  protein transport  response to testosterone  histone binding  protein complex  histone exchange  Hsp90 protein binding  
Ontology : EGO-EBInuclear chromatin  blastocyst development  protein binding  nucleus  nucleoplasm  cytoplasm  DNA replication  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  cell cycle  cell proliferation  male gonad development  protein transport  response to testosterone  histone binding  protein complex  histone exchange  Hsp90 protein binding  
NDEx NetworkNASP
Atlas of Cancer Signalling NetworkNASP
Wikipedia pathwaysNASP
Orthology - Evolution
OrthoDB4678
GeneTree (enSembl)ENSG00000132780
Phylogenetic Trees/Animal Genes : TreeFamNASP
HOVERGENP49321
HOGENOMP49321
Homologs : HomoloGeneNASP
Homology/Alignments : Family Browser (UCSC)NASP
Gene fusions - Rearrangements
Fusion : MitelmanMAST2/NASP [1p34.1/1p34.1]  [t(1;1)(p34;p34)]  
Fusion : MitelmanNASP/WIPF1 [1p34.1/2q31.1]  [t(1;2)(p34;q31)]  
Fusion: TCGAMAST2 1p34.1 NASP 1p34.1 BRCA
Fusion Cancer (Beijing)NASP [1p34.1]  -  AC022182.1 [FUSC001663]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNASP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NASP
dbVarNASP
ClinVarNASP
1000_GenomesNASP 
Exome Variant ServerNASP
ExAC (Exome Aggregation Consortium)NASP (select the gene name)
Genetic variants : HAPMAP4678
Genomic Variants (DGV)NASP [DGVbeta]
DECIPHERNASP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNASP 
Mutations
ICGC Data PortalNASP 
TCGA Data PortalNASP 
Broad Tumor PortalNASP
OASIS PortalNASP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNASP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNASP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NASP
DgiDB (Drug Gene Interaction Database)NASP
DoCM (Curated mutations)NASP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NASP (select a term)
intoGenNASP
Cancer3DNASP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603185   
Orphanet
MedgenNASP
Genetic Testing Registry NASP
NextProtP49321 [Medical]
TSGene4678
GENETestsNASP
Target ValidationNASP
Huge Navigator NASP [HugePedia]
snp3D : Map Gene to Disease4678
BioCentury BCIQNASP
ClinGenNASP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4678
Chemical/Pharm GKB GenePA31448
Clinical trialNASP
Miscellaneous
canSAR (ICR)NASP (select the gene name)
Probes
Litterature
PubMed76 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNASP
EVEXNASP
GoPubMedNASP
iHOPNASP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:21:25 CEST 2017

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