Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NAT8 (N-acetyltransferase 8 (putative))

Identity

Alias (NCBI)ATase2
CCNAT
CML1
GLA
Hcml1
TSC501
TSC510
HGNC (Hugo) NAT8
HGNC Alias symbHcml1
TSC501
GLA
ATase2
HGNC Previous nameN-acetyltransferase 8
 N-acetyltransferase 8 (GCN5-related, putative)
LocusID (NCBI) 9027
Atlas_Id 55841
Location 2p13.1  [Link to chromosome band 2p13]
Location_base_pair Starts at 73640723 and ends at 73642422 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)NAT8   18069
Cards
Entrez_Gene (NCBI)NAT8    N-acetyltransferase 8 (putative)
AliasesATase2; CCNAT; CML1; GLA; 
Hcml1; TSC501; TSC510
GeneCards (Weizmann)NAT8
Ensembl hg19 (Hinxton)ENSG00000144035 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144035 [Gene_View]  ENSG00000144035 [Sequence]  chr2:73640723-73642422 [Contig_View]  NAT8 [Vega]
ICGC DataPortalENSG00000144035
TCGA cBioPortalNAT8
AceView (NCBI)NAT8
Genatlas (Paris)NAT8
SOURCE (Princeton)NAT8
Genetics Home Reference (NIH)NAT8
Genomic and cartography
GoldenPath hg38 (UCSC)NAT8  -     chr2:73640723-73642422 -  2p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NAT8  -     2p13.1   [Description]    (hg19-Feb_2009)
GoldenPathNAT8 - 2p13.1 [CytoView hg19]  NAT8 - 2p13.1 [CytoView hg38]
ImmunoBaseENSG00000144035
Genome Data Viewer NCBINAT8 [Mapview hg19]  
OMIM606716   
Gene and transcription
Genbank (Entrez)AB013094 AB019551 AF187813 BC012626 BG426653
RefSeq transcript (Entrez)NM_003960
Consensus coding sequences : CCDS (NCBI)NAT8
Gene ExpressionNAT8 [ NCBI-GEO ]   NAT8 [ EBI - ARRAY_EXPRESS ]   NAT8 [ SEEK ]   NAT8 [ MEM ]
Gene Expression Viewer (FireBrowse)NAT8 [ Firebrowse - Broad ]
GenevisibleExpression of NAT8 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9027
GTEX Portal (Tissue expression)NAT8
Human Protein AtlasENSG00000144035-NAT8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UHE5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UHE5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UHE5
Catalytic activity : Enzyme2.3.1.- [ Enzyme-Expasy ]   2.3.1.-2.3.1.- [ IntEnz-EBI ]   2.3.1.- [ BRENDA ]   2.3.1.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ9UHE5
Domaine pattern : Prosite (Expaxy)GNAT (PS51186)   
Domains : Interpro (EBI)Acyl_CoA_acyltransferase    GNAT_dom   
Domain families : Pfam (Sanger)Acetyltransf_1 (PF00583)   
Domain families : Pfam (NCBI)pfam00583   
Conserved Domain (NCBI)NAT8
SuperfamilyQ9UHE5
AlphaFold pdb e-kbQ9UHE5   
Human Protein Atlas [tissue]ENSG00000144035-NAT8 [tissue]
HPRD08413
Protein Interaction databases
DIP (DOE-UCLA)Q9UHE5
IntAct (EBI)Q9UHE5
BioGRIDNAT8
STRING (EMBL)NAT8
ZODIACNAT8
Ontologies - Pathways
QuickGOQ9UHE5
Ontology : AmiGOlysine N-acetyltransferase activity, acting on acetyl phosphate as donor  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum membrane  endoplasmic reticulum-Golgi intermediate compartment  glutathione metabolic process  glutathione metabolic process  N-acetyltransferase activity  positive regulation of gene expression  integral component of membrane  peptidyl-lysine N6-acetylation  endoplasmic reticulum-Golgi intermediate compartment membrane  response to drug  negative regulation of apoptotic process  cysteine-S-conjugate N-acetyltransferase activity  amyloid-beta metabolic process  amyloid fibril formation  
Ontology : EGO-EBIlysine N-acetyltransferase activity, acting on acetyl phosphate as donor  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  endoplasmic reticulum membrane  endoplasmic reticulum-Golgi intermediate compartment  glutathione metabolic process  glutathione metabolic process  N-acetyltransferase activity  positive regulation of gene expression  integral component of membrane  peptidyl-lysine N6-acetylation  endoplasmic reticulum-Golgi intermediate compartment membrane  response to drug  negative regulation of apoptotic process  cysteine-S-conjugate N-acetyltransferase activity  amyloid-beta metabolic process  amyloid fibril formation  
NDEx NetworkNAT8
Atlas of Cancer Signalling NetworkNAT8
Wikipedia pathwaysNAT8
Orthology - Evolution
OrthoDB9027
GeneTree (enSembl)ENSG00000144035
Phylogenetic Trees/Animal Genes : TreeFamNAT8
Homologs : HomoloGeneNAT8
Homology/Alignments : Family Browser (UCSC)NAT8
Gene fusions - Rearrangements
Fusion : QuiverNAT8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNAT8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NAT8
dbVarNAT8
ClinVarNAT8
MonarchNAT8
1000_GenomesNAT8 
Exome Variant ServerNAT8
GNOMAD BrowserENSG00000144035
Varsome BrowserNAT8
ACMGNAT8 variants
VarityQ9UHE5
Genomic Variants (DGV)NAT8 [DGVbeta]
DECIPHERNAT8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNAT8 
Mutations
ICGC Data PortalNAT8 
TCGA Data PortalNAT8 
Broad Tumor PortalNAT8
OASIS PortalNAT8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNAT8  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNAT8
Mutations and Diseases : HGMDNAT8
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNAT8
DgiDB (Drug Gene Interaction Database)NAT8
DoCM (Curated mutations)NAT8
CIViC (Clinical Interpretations of Variants in Cancer)NAT8
Cancer3DNAT8
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606716   
Orphanet
DisGeNETNAT8
MedgenNAT8
Genetic Testing Registry NAT8
NextProtQ9UHE5 [Medical]
GENETestsNAT8
Target ValidationNAT8
Huge Navigator NAT8 [HugePedia]
ClinGenNAT8
Clinical trials, drugs, therapy
MyCancerGenomeNAT8
Protein Interactions : CTDNAT8
Pharm GKB GenePA31450
PharosQ9UHE5
Clinical trialNAT8
Miscellaneous
canSAR (ICR)NAT8
HarmonizomeNAT8
DataMed IndexNAT8
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNAT8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:22:05 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.