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NAT8L (N-acetyltransferase 8 like)

Identity

Alias_namesN-acetyltransferase 8-like (GCN5-related
Alias_symbol (synonym)FLJ37478
Hcml3
Other aliasCML3
NACED
NAT8-LIKE
HGNC (Hugo) NAT8L
LocusID (NCBI) 339983
Atlas_Id 54488
Location 4p16.3  [Link to chromosome band 4p16]
Location_base_pair Starts at 2059512 and ends at 2069089 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MYCBP2 (13q22.3) / NAT8L (4p16.3)NAT8L (4p16.3) / DBNDD1 (16q24.3)NAT8L (4p16.3) / MDM4 (1q32.1)
NAT8L 4p16.3 / DBNDD1 16q24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NAT8L   26742
Cards
Entrez_Gene (NCBI)NAT8L  339983  N-acetyltransferase 8 like
AliasesCML3; NACED; NAT8-LIKE
GeneCards (Weizmann)NAT8L
Ensembl hg19 (Hinxton)ENSG00000185818 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185818 [Gene_View]  chr4:2059512-2069089 [Contig_View]  NAT8L [Vega]
ICGC DataPortalENSG00000185818
TCGA cBioPortalNAT8L
AceView (NCBI)NAT8L
Genatlas (Paris)NAT8L
WikiGenes339983
SOURCE (Princeton)NAT8L
Genetics Home Reference (NIH)NAT8L
Genomic and cartography
GoldenPath hg38 (UCSC)NAT8L  -     chr4:2059512-2069089 +  4p16.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NAT8L  -     4p16.3   [Description]    (hg19-Feb_2009)
EnsemblNAT8L - 4p16.3 [CytoView hg19]  NAT8L - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBINAT8L [Mapview hg19]  NAT8L [Mapview hg38]
OMIM610647   614063   
Gene and transcription
Genbank (Entrez)AK094797 BC010045 BC093906 BC093908 BC103748
RefSeq transcript (Entrez)NM_178557
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NAT8L
Cluster EST : UnigeneHs.318529 [ NCBI ]
CGAP (NCI)Hs.318529
Alternative Splicing GalleryENSG00000185818
Gene ExpressionNAT8L [ NCBI-GEO ]   NAT8L [ EBI - ARRAY_EXPRESS ]   NAT8L [ SEEK ]   NAT8L [ MEM ]
Gene Expression Viewer (FireBrowse)NAT8L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)339983
GTEX Portal (Tissue expression)NAT8L
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N9F0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N9F0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N9F0
Splice isoforms : SwissVarQ8N9F0
Catalytic activity : Enzyme2.3.1.17 [ Enzyme-Expasy ]   2.3.1.172.3.1.17 [ IntEnz-EBI ]   2.3.1.17 [ BRENDA ]   2.3.1.17 [ KEGG ]   
PhosPhoSitePlusQ8N9F0
Domaine pattern : Prosite (Expaxy)GNAT (PS51186)   
Domains : Interpro (EBI)Acyl_CoA_acyltransferase    GNAT_dom   
Domain families : Pfam (Sanger)Acetyltransf_1 (PF00583)   
Domain families : Pfam (NCBI)pfam00583   
Conserved Domain (NCBI)NAT8L
DMDM Disease mutations339983
Blocks (Seattle)NAT8L
SuperfamilyQ8N9F0
Human Protein AtlasENSG00000185818
Peptide AtlasQ8N9F0
HPRD08224
IPIIPI00167703   IPI00552379   IPI01009152   
Protein Interaction databases
DIP (DOE-UCLA)Q8N9F0
IntAct (EBI)Q8N9F0
FunCoupENSG00000185818
BioGRIDNAT8L
STRING (EMBL)NAT8L
ZODIACNAT8L
Ontologies - Pathways
QuickGOQ8N9F0
Ontology : AmiGOcytoplasm  mitochondrion  integral component of membrane  aspartate N-acetyltransferase activity  rough endoplasmic reticulum membrane  mitochondrial membrane  
Ontology : EGO-EBIcytoplasm  mitochondrion  integral component of membrane  aspartate N-acetyltransferase activity  rough endoplasmic reticulum membrane  mitochondrial membrane  
NDEx NetworkNAT8L
Atlas of Cancer Signalling NetworkNAT8L
Wikipedia pathwaysNAT8L
Orthology - Evolution
OrthoDB339983
GeneTree (enSembl)ENSG00000185818
Phylogenetic Trees/Animal Genes : TreeFamNAT8L
HOVERGENQ8N9F0
HOGENOMQ8N9F0
Homologs : HomoloGeneNAT8L
Homology/Alignments : Family Browser (UCSC)NAT8L
Gene fusions - Rearrangements
Fusion : MitelmanNAT8L/DBNDD1 [4p16.3/16q24.3]  
Fusion: TCGANAT8L 4p16.3 DBNDD1 16q24.3 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNAT8L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NAT8L
dbVarNAT8L
ClinVarNAT8L
1000_GenomesNAT8L 
Exome Variant ServerNAT8L
ExAC (Exome Aggregation Consortium)NAT8L (select the gene name)
Genetic variants : HAPMAP339983
Genomic Variants (DGV)NAT8L [DGVbeta]
DECIPHERNAT8L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNAT8L 
Mutations
ICGC Data PortalNAT8L 
TCGA Data PortalNAT8L 
Broad Tumor PortalNAT8L
OASIS PortalNAT8L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNAT8L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNAT8L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NAT8L
DgiDB (Drug Gene Interaction Database)NAT8L
DoCM (Curated mutations)NAT8L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NAT8L (select a term)
intoGenNAT8L
Cancer3DNAT8L(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610647    614063   
Orphanet
MedgenNAT8L
Genetic Testing Registry NAT8L
NextProtQ8N9F0 [Medical]
TSGene339983
GENETestsNAT8L
Huge Navigator NAT8L [HugePedia]
snp3D : Map Gene to Disease339983
BioCentury BCIQNAT8L
ClinGenNAT8L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD339983
Chemical/Pharm GKB GenePA162396985
Clinical trialNAT8L
Miscellaneous
canSAR (ICR)NAT8L (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNAT8L
EVEXNAT8L
GoPubMedNAT8L
iHOPNAT8L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:27:58 CEST 2017

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