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NBAS (neuroblastoma amplified sequence)

Identity

Alias_symbol (synonym)NAG
Other aliasILFS2
SOPH
HGNC (Hugo) NBAS
LocusID (NCBI) 51594
Atlas_Id 41492
Location 2p24.3  [Link to chromosome band 2p24]
Location_base_pair Starts at 15166908 and ends at 15561348 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CLEC16A (16p13.13) / NBAS (2p24.3)EZR (6q25.3) / NBAS (2p24.3)LUC7L2 (7q34) / NBAS (2p24.3)
MCM6 (2q21.3) / NBAS (2p24.3)NBAS (2p24.3) / ARL6IP5 (3p14.1)NBAS (2p24.3) / BAZ2B (2q24.2)
NBAS (2p24.3) / CCNT2 (2q21.3)NBAS (2p24.3) / DDX1 (2p24.3)NBAS (2p24.3) / EIF4G2 (11p15.3)
NBAS (2p24.3) / PRRC2C (1q24.3)NBAS (2p24.3) / THADA (2p21)PTPRO (12p12.3) / NBAS (2p24.3)
ROCK2 (2p25.1) / NBAS (2p24.3)SDHA (5p15.33) / NBAS (2p24.3)SKA1 (18q21.1) / NBAS (2p24.3)
NBAS 2p24.3 / DDX1 2p24.3NBAS 2p24.3 / THADA 2p21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Nervous system: Peripheral neuroblastic tumours (Neuroblastoma, Ganglioneuroblastoma, Ganglioneuroma)


External links

Nomenclature
HGNC (Hugo)NBAS   15625
Cards
Entrez_Gene (NCBI)NBAS  51594  neuroblastoma amplified sequence
AliasesILFS2; NAG; SOPH
GeneCards (Weizmann)NBAS
Ensembl hg19 (Hinxton)ENSG00000151779 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151779 [Gene_View]  chr2:15166908-15561348 [Contig_View]  NBAS [Vega]
ICGC DataPortalENSG00000151779
TCGA cBioPortalNBAS
AceView (NCBI)NBAS
Genatlas (Paris)NBAS
WikiGenes51594
SOURCE (Princeton)NBAS
Genetics Home Reference (NIH)NBAS
Genomic and cartography
GoldenPath hg38 (UCSC)NBAS  -     chr2:15166908-15561348 -  2p24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NBAS  -     2p24.3   [Description]    (hg19-Feb_2009)
EnsemblNBAS - 2p24.3 [CytoView hg19]  NBAS - 2p24.3 [CytoView hg38]
Mapping of homologs : NCBINBAS [Mapview hg19]  NBAS [Mapview hg38]
OMIM608025   614800   616483   
Gene and transcription
Genbank (Entrez)AB621813 AF056195 AF388385 AK057915 AK097726
RefSeq transcript (Entrez)NM_015909
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NBAS
Cluster EST : UnigeneHs.467759 [ NCBI ]
CGAP (NCI)Hs.467759
Alternative Splicing GalleryENSG00000151779
Gene ExpressionNBAS [ NCBI-GEO ]   NBAS [ EBI - ARRAY_EXPRESS ]   NBAS [ SEEK ]   NBAS [ MEM ]
Gene Expression Viewer (FireBrowse)NBAS [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51594
GTEX Portal (Tissue expression)NBAS
Human Protein AtlasENSG00000151779-NBAS [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA2RRP1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA2RRP1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA2RRP1
Splice isoforms : SwissVarA2RRP1
PhosPhoSitePlusA2RRP1
Domains : Interpro (EBI)NBAS_N    Quino_amine_DH_bsu    Sec39_domain    WD40/YVTN_repeat-like_dom   
Domain families : Pfam (Sanger)Nbas_N (PF15492)    Sec39 (PF08314)   
Domain families : Pfam (NCBI)pfam15492    pfam08314   
Conserved Domain (NCBI)NBAS
DMDM Disease mutations51594
Blocks (Seattle)NBAS
SuperfamilyA2RRP1
Human Protein Atlas [tissue]ENSG00000151779-NBAS [tissue]
Peptide AtlasA2RRP1
HPRD10473
IPIIPI00333913   IPI00847551   IPI00985297   IPI00894369   IPI00893725   IPI00894071   IPI00894456   IPI00892676   IPI00892571   
Protein Interaction databases
DIP (DOE-UCLA)A2RRP1
IntAct (EBI)A2RRP1
FunCoupENSG00000151779
BioGRIDNBAS
STRING (EMBL)NBAS
ZODIACNBAS
Ontologies - Pathways
QuickGOA2RRP1
Ontology : AmiGOSNARE binding  nuclear-transcribed mRNA catabolic process  endoplasmic reticulum  endoplasmic reticulum membrane  cytosol  retrograde vesicle-mediated transport, Golgi to ER  retrograde vesicle-mediated transport, Golgi to ER  protein transport  membrane  Dsl1/NZR complex  negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  
Ontology : EGO-EBISNARE binding  nuclear-transcribed mRNA catabolic process  endoplasmic reticulum  endoplasmic reticulum membrane  cytosol  retrograde vesicle-mediated transport, Golgi to ER  retrograde vesicle-mediated transport, Golgi to ER  protein transport  membrane  Dsl1/NZR complex  negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  
NDEx NetworkNBAS
Atlas of Cancer Signalling NetworkNBAS
Wikipedia pathwaysNBAS
Orthology - Evolution
OrthoDB51594
GeneTree (enSembl)ENSG00000151779
Phylogenetic Trees/Animal Genes : TreeFamNBAS
HOVERGENA2RRP1
HOGENOMA2RRP1
Homologs : HomoloGeneNBAS
Homology/Alignments : Family Browser (UCSC)NBAS
Gene fusions - Rearrangements
Fusion : MitelmanNBAS/BAZ2B [2p24.3/2q24.2]  
Fusion : MitelmanNBAS/CCNT2 [2p24.3/2q21.3]  [t(2;2)(p24;q21)]  
Fusion : MitelmanNBAS/DDX1 [2p24.3/2p24.3]  [t(2;2)(p24;p24)]  
Fusion : MitelmanNBAS/THADA [2p24.3/2p21]  [t(2;2)(p21;p24)]  
Fusion: TCGA_MDACCNBAS 2p24.3 DDX1 2p24.3 LUSC
Fusion: TCGA_MDACCNBAS 2p24.3 THADA 2p21 BRCA
Tumor Fusion PortalNBAS
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNBAS [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NBAS
dbVarNBAS
ClinVarNBAS
1000_GenomesNBAS 
Exome Variant ServerNBAS
ExAC (Exome Aggregation Consortium)ENSG00000151779
GNOMAD BrowserENSG00000151779
Genetic variants : HAPMAP51594
Genomic Variants (DGV)NBAS [DGVbeta]
DECIPHERNBAS [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNBAS 
Mutations
ICGC Data PortalNBAS 
TCGA Data PortalNBAS 
Broad Tumor PortalNBAS
OASIS PortalNBAS [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNBAS  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNBAS
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NBAS
DgiDB (Drug Gene Interaction Database)NBAS
DoCM (Curated mutations)NBAS (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NBAS (select a term)
intoGenNBAS
Cancer3DNBAS(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608025    614800    616483   
Orphanet22641   
DisGeNETNBAS
MedgenNBAS
Genetic Testing Registry NBAS
NextProtA2RRP1 [Medical]
TSGene51594
GENETestsNBAS
Target ValidationNBAS
Huge Navigator NBAS [HugePedia]
snp3D : Map Gene to Disease51594
BioCentury BCIQNBAS
ClinGenNBAS
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51594
Chemical/Pharm GKB GenePA164723457
Clinical trialNBAS
Miscellaneous
canSAR (ICR)NBAS (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNBAS
EVEXNBAS
GoPubMedNBAS
iHOPNBAS
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:25:34 CET 2017

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