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NBL1 (neuroblastoma 1, DAN family BMP antagonist)

Identity

Alias_namesneuroblastoma
Alias_symbol (synonym)D1S1733E
NB
DAN
NO3
DAND1
Other alias
HGNC (Hugo) NBL1
LocusID (NCBI) 4681
Atlas_Id 41501
Location 1p36.13  [Link to chromosome band 1p36]
Location_base_pair Starts at 19970208 and ends at 19984949 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NBL1   7650
Cards
Entrez_Gene (NCBI)NBL1  4681  neuroblastoma 1, DAN family BMP antagonist
AliasesD1S1733E; DAN; DAND1; NB; 
NO3
GeneCards (Weizmann)NBL1
Ensembl hg19 (Hinxton)ENSG00000158747 [Gene_View]  chr1:19970208-19984949 [Contig_View]  NBL1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000158747 [Gene_View]  chr1:19970208-19984949 [Contig_View]  NBL1 [Vega]
ICGC DataPortalENSG00000158747
TCGA cBioPortalNBL1
AceView (NCBI)NBL1
Genatlas (Paris)NBL1
WikiGenes4681
SOURCE (Princeton)NBL1
Genetics Home Reference (NIH)NBL1
Genomic and cartography
GoldenPath hg19 (UCSC)NBL1  -     chr1:19970208-19984949 +  1p36.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NBL1  -     1p36.13   [Description]    (hg38-Dec_2013)
EnsemblNBL1 - 1p36.13 [CytoView hg19]  NBL1 - 1p36.13 [CytoView hg38]
Mapping of homologs : NCBINBL1 [Mapview hg19]  NBL1 [Mapview hg38]
OMIM600613   
Gene and transcription
Genbank (Entrez)AK292101 AK300872 AK309257 AK313265 AL703187
RefSeq transcript (Entrez)NM_001204084 NM_001204085 NM_001204086 NM_001278164 NM_001278165 NM_001278166 NM_005380 NM_182744
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929289
Consensus coding sequences : CCDS (NCBI)NBL1
Cluster EST : UnigeneHs.654502 [ NCBI ]
CGAP (NCI)Hs.654502
Alternative Splicing GalleryENSG00000158747
Gene ExpressionNBL1 [ NCBI-GEO ]   NBL1 [ EBI - ARRAY_EXPRESS ]   NBL1 [ SEEK ]   NBL1 [ MEM ]
Gene Expression Viewer (FireBrowse)NBL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4681
GTEX Portal (Tissue expression)NBL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP41271   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP41271  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP41271
Splice isoforms : SwissVarP41271
PhosPhoSitePlusP41271
Domains : Interpro (EBI)Cys_knot_C    Cystine-knot_cytokine    DAN    Neuroblast_suppress_tumour_1   
Domain families : Pfam (Sanger)DAN (PF03045)   
Domain families : Pfam (NCBI)pfam03045   
Domain families : Smart (EMBL)CT (SM00041)  
Conserved Domain (NCBI)NBL1
DMDM Disease mutations4681
Blocks (Seattle)NBL1
PDB (SRS)4X1J    4YU8   
PDB (PDBSum)4X1J    4YU8   
PDB (IMB)4X1J    4YU8   
PDB (RSDB)4X1J    4YU8   
Structural Biology KnowledgeBase4X1J    4YU8   
SCOP (Structural Classification of Proteins)4X1J    4YU8   
CATH (Classification of proteins structures)4X1J    4YU8   
SuperfamilyP41271
Human Protein AtlasENSG00000158747
Peptide AtlasP41271
HPRD09001
IPIIPI00852617   IPI00844060   IPI00748646   IPI00853585   IPI00853496   IPI00853441   IPI00852846   IPI00852703   
Protein Interaction databases
DIP (DOE-UCLA)P41271
IntAct (EBI)P41271
FunCoupENSG00000158747
BioGRIDNBL1
STRING (EMBL)NBL1
ZODIACNBL1
Ontologies - Pathways
QuickGOP41271
Ontology : AmiGOprotein binding  extracellular space  nervous system development  morphogen activity  negative regulation of BMP signaling pathway  sequestering of BMP in extracellular matrix  BMP binding  sequestering of BMP from receptor via BMP binding  protein homodimerization activity  positive regulation of neuron differentiation  determination of dorsal identity  neuron projection morphogenesis  negative regulation of monocyte chemotaxis  
Ontology : EGO-EBIprotein binding  extracellular space  nervous system development  morphogen activity  negative regulation of BMP signaling pathway  sequestering of BMP in extracellular matrix  BMP binding  sequestering of BMP from receptor via BMP binding  protein homodimerization activity  positive regulation of neuron differentiation  determination of dorsal identity  neuron projection morphogenesis  negative regulation of monocyte chemotaxis  
NDEx NetworkNBL1
Atlas of Cancer Signalling NetworkNBL1
Wikipedia pathwaysNBL1
Orthology - Evolution
OrthoDB4681
GeneTree (enSembl)ENSG00000158747
Phylogenetic Trees/Animal Genes : TreeFamNBL1
HOVERGENP41271
HOGENOMP41271
Homologs : HomoloGeneNBL1
Homology/Alignments : Family Browser (UCSC)NBL1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNBL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NBL1
dbVarNBL1
ClinVarNBL1
1000_GenomesNBL1 
Exome Variant ServerNBL1
ExAC (Exome Aggregation Consortium)NBL1 (select the gene name)
Genetic variants : HAPMAP4681
Genomic Variants (DGV)NBL1 [DGVbeta]
DECIPHER (Syndromes)1:19970208-19984949  ENSG00000158747
CONAN: Copy Number AnalysisNBL1 
Mutations
ICGC Data PortalNBL1 
TCGA Data PortalNBL1 
Broad Tumor PortalNBL1
OASIS PortalNBL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNBL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNBL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NBL1
DgiDB (Drug Gene Interaction Database)NBL1
DoCM (Curated mutations)NBL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NBL1 (select a term)
intoGenNBL1
Cancer3DNBL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600613   
Orphanet
MedgenNBL1
Genetic Testing Registry NBL1
NextProtP41271 [Medical]
TSGene4681
GENETestsNBL1
Huge Navigator NBL1 [HugePedia]
snp3D : Map Gene to Disease4681
BioCentury BCIQNBL1
ClinGenNBL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4681
Chemical/Pharm GKB GenePA31456
Clinical trialNBL1
Miscellaneous
canSAR (ICR)NBL1 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNBL1
EVEXNBL1
GoPubMedNBL1
iHOPNBL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:18:11 CET 2017

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