Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NCBP2 (nuclear cap binding protein subunit 2)

Identity

Alias_namesnuclear cap binding protein subunit 2, 20kD
nuclear cap binding protein subunit 2, 20kDa
Alias_symbol (synonym)NIP1
CBP20
Cbc2
Other aliasCBC2
PIG55
HGNC (Hugo) NCBP2
LocusID (NCBI) 22916
Atlas_Id 70731
Location 3q29  [Link to chromosome band 3q29]
Location_base_pair Starts at 196935402 and ends at 196942593 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NCBP2 (3q29) / FBXL2 (3p22.3)NCBP2 (3q29) / GDF9 (5q31.1)NCBP2 (3q29) / PEX5 (12p13.31)
YBX1 (1p34.2) / NCBP2 (3q29)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NCBP2   7659
Cards
Entrez_Gene (NCBI)NCBP2  22916  nuclear cap binding protein subunit 2
AliasesCBC2; CBP20; NIP1; PIG55
GeneCards (Weizmann)NCBP2
Ensembl hg19 (Hinxton)ENSG00000114503 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000114503 [Gene_View]  chr3:196935402-196942593 [Contig_View]  NCBP2 [Vega]
ICGC DataPortalENSG00000114503
TCGA cBioPortalNCBP2
AceView (NCBI)NCBP2
Genatlas (Paris)NCBP2
WikiGenes22916
SOURCE (Princeton)NCBP2
Genetics Home Reference (NIH)NCBP2
Genomic and cartography
GoldenPath hg38 (UCSC)NCBP2  -     chr3:196935402-196942593 -  3q29   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NCBP2  -     3q29   [Description]    (hg19-Feb_2009)
EnsemblNCBP2 - 3q29 [CytoView hg19]  NCBP2 - 3q29 [CytoView hg38]
Mapping of homologs : NCBINCBP2 [Mapview hg19]  NCBP2 [Mapview hg38]
OMIM605133   
Gene and transcription
Genbank (Entrez)AK093216 AK296144 AK297506 AK308192 AK315903
RefSeq transcript (Entrez)NM_001042540 NM_001308036 NM_007362
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NCBP2
Cluster EST : UnigeneHs.591671 [ NCBI ]
CGAP (NCI)Hs.591671
Alternative Splicing GalleryENSG00000114503
Gene ExpressionNCBP2 [ NCBI-GEO ]   NCBP2 [ EBI - ARRAY_EXPRESS ]   NCBP2 [ SEEK ]   NCBP2 [ MEM ]
Gene Expression Viewer (FireBrowse)NCBP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)22916
GTEX Portal (Tissue expression)NCBP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP52298   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP52298  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP52298
Splice isoforms : SwissVarP52298
PhosPhoSitePlusP52298
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)NCBP2    NCBP2_RRM    Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)NCBP2
DMDM Disease mutations22916
Blocks (Seattle)NCBP2
PDB (SRS)1H2T    1H2U    1H2V    1H6K    1N52    1N54    3FEX    3FEY   
PDB (PDBSum)1H2T    1H2U    1H2V    1H6K    1N52    1N54    3FEX    3FEY   
PDB (IMB)1H2T    1H2U    1H2V    1H6K    1N52    1N54    3FEX    3FEY   
PDB (RSDB)1H2T    1H2U    1H2V    1H6K    1N52    1N54    3FEX    3FEY   
Structural Biology KnowledgeBase1H2T    1H2U    1H2V    1H6K    1N52    1N54    3FEX    3FEY   
SCOP (Structural Classification of Proteins)1H2T    1H2U    1H2V    1H6K    1N52    1N54    3FEX    3FEY   
CATH (Classification of proteins structures)1H2T    1H2U    1H2V    1H6K    1N52    1N54    3FEX    3FEY   
SuperfamilyP52298
Human Protein AtlasENSG00000114503
Peptide AtlasP52298
HPRD05503
IPIIPI00183500   IPI00927860   IPI01021019   IPI00784189   IPI00927631   IPI00789410   IPI00924867   IPI00924846   
Protein Interaction databases
DIP (DOE-UCLA)P52298
IntAct (EBI)P52298
FunCoupENSG00000114503
BioGRIDNCBP2
STRING (EMBL)NCBP2
ZODIACNCBP2
Ontologies - Pathways
QuickGOP52298
Ontology : AmiGOnuclear-transcribed mRNA catabolic process, nonsense-mediated decay  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  RNA cap binding  RNA 7-methylguanosine cap binding  RNA 7-methylguanosine cap binding  mRNA splicing, via spliceosome  RNA binding  RNA binding  mRNA binding  protein binding  nucleus  nucleus  nucleoplasm  nucleoplasm  cytoplasm  cytosol  mRNA cap binding complex  nuclear cap binding complex  transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  termination of RNA polymerase II transcription  7-methylguanosine mRNA capping  RNA export from nucleus  mRNA export from nucleus  snRNA export from nucleus  snRNA export from nucleus  regulation of translational initiation  histone mRNA metabolic process  RNA splicing  fibroblast growth factor receptor signaling pathway  gene expression  snRNA binding  gene silencing by RNA  mRNA 3'-end processing  positive regulation of mRNA 3'-end processing  RNA cap binding complex  snRNA transcription from RNA polymerase II promoter  mRNA cis splicing, via spliceosome  positive regulation of RNA export from nucleus  nuclear export  pre-mRNA cleavage required for polyadenylation  regulation of mRNA polyadenylation  
Ontology : EGO-EBInuclear-transcribed mRNA catabolic process, nonsense-mediated decay  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay  RNA cap binding  RNA 7-methylguanosine cap binding  RNA 7-methylguanosine cap binding  mRNA splicing, via spliceosome  RNA binding  RNA binding  mRNA binding  protein binding  nucleus  nucleus  nucleoplasm  nucleoplasm  cytoplasm  cytosol  mRNA cap binding complex  nuclear cap binding complex  transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  termination of RNA polymerase II transcription  7-methylguanosine mRNA capping  RNA export from nucleus  mRNA export from nucleus  snRNA export from nucleus  snRNA export from nucleus  regulation of translational initiation  histone mRNA metabolic process  RNA splicing  fibroblast growth factor receptor signaling pathway  gene expression  snRNA binding  gene silencing by RNA  mRNA 3'-end processing  positive regulation of mRNA 3'-end processing  RNA cap binding complex  snRNA transcription from RNA polymerase II promoter  mRNA cis splicing, via spliceosome  positive regulation of RNA export from nucleus  nuclear export  pre-mRNA cleavage required for polyadenylation  regulation of mRNA polyadenylation  
Pathways : KEGGRNA transport    mRNA surveillance pathway    Spliceosome   
NDEx NetworkNCBP2
Atlas of Cancer Signalling NetworkNCBP2
Wikipedia pathwaysNCBP2
Orthology - Evolution
OrthoDB22916
GeneTree (enSembl)ENSG00000114503
Phylogenetic Trees/Animal Genes : TreeFamNCBP2
HOVERGENP52298
HOGENOMP52298
Homologs : HomoloGeneNCBP2
Homology/Alignments : Family Browser (UCSC)NCBP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNCBP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NCBP2
dbVarNCBP2
ClinVarNCBP2
1000_GenomesNCBP2 
Exome Variant ServerNCBP2
ExAC (Exome Aggregation Consortium)NCBP2 (select the gene name)
Genetic variants : HAPMAP22916
Genomic Variants (DGV)NCBP2 [DGVbeta]
DECIPHERNCBP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNCBP2 
Mutations
ICGC Data PortalNCBP2 
TCGA Data PortalNCBP2 
Broad Tumor PortalNCBP2
OASIS PortalNCBP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNCBP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNCBP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NCBP2
DgiDB (Drug Gene Interaction Database)NCBP2
DoCM (Curated mutations)NCBP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NCBP2 (select a term)
intoGenNCBP2
Cancer3DNCBP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605133   
Orphanet
MedgenNCBP2
Genetic Testing Registry NCBP2
NextProtP52298 [Medical]
TSGene22916
GENETestsNCBP2
Target ValidationNCBP2
Huge Navigator NCBP2 [HugePedia]
snp3D : Map Gene to Disease22916
BioCentury BCIQNCBP2
ClinGenNCBP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD22916
Chemical/Pharm GKB GenePA31462
Clinical trialNCBP2
Miscellaneous
canSAR (ICR)NCBP2 (select the gene name)
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNCBP2
EVEXNCBP2
GoPubMedNCBP2
iHOPNCBP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:31:47 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.