Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NCEH1 (neutral cholesterol ester hydrolase 1)

Identity

Alias_namesAADACL1
arylacetamide deacetylase-like 1
Alias_symbol (synonym)KIAA1363
NCEH
Other alias
HGNC (Hugo) NCEH1
LocusID (NCBI) 57552
Atlas_Id 51009
Location 3q26.31  [Link to chromosome band 3q26]
Location_base_pair Starts at 172348435 and ends at 172429008 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GOLIM4 (3q26.2) / NCEH1 (3q26.31)GPR160 (3q26.2) / NCEH1 (3q26.31)H19 (11p15.5) / NCEH1 (3q26.31)
IGF2BP2 (3q27.2) / NCEH1 (3q26.31)NCEH1 (3q26.31) / NCEH1 (3q26.31)NCEH1 (3q26.31) / SPATA16 (3q26.31)
RPL31 (2q11.2) / NCEH1 (3q26.31)GOLIM4 3q26.2 / NCEH1 3q26.31IGF2BP2 3q27.2 / NCEH1 3q26.31
NCEH1 3q26.31 / SPATA16 3q26.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Small Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)NCEH1   29260
Cards
Entrez_Gene (NCBI)NCEH1  57552  neutral cholesterol ester hydrolase 1
AliasesAADACL1; NCEH
GeneCards (Weizmann)NCEH1
Ensembl hg19 (Hinxton)ENSG00000144959 [Gene_View]  chr3:172348435-172429008 [Contig_View]  NCEH1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000144959 [Gene_View]  chr3:172348435-172429008 [Contig_View]  NCEH1 [Vega]
ICGC DataPortalENSG00000144959
TCGA cBioPortalNCEH1
AceView (NCBI)NCEH1
Genatlas (Paris)NCEH1
WikiGenes57552
SOURCE (Princeton)NCEH1
Genetics Home Reference (NIH)NCEH1
Genomic and cartography
GoldenPath hg19 (UCSC)NCEH1  -     chr3:172348435-172429008 -  3q26.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NCEH1  -     3q26.31   [Description]    (hg38-Dec_2013)
EnsemblNCEH1 - 3q26.31 [CytoView hg19]  NCEH1 - 3q26.31 [CytoView hg38]
Mapping of homologs : NCBINCEH1 [Mapview hg19]  NCEH1 [Mapview hg38]
OMIM613234   
Gene and transcription
Genbank (Entrez)AB037784 AK294811 AK295641 AK299422 AK304253
RefSeq transcript (Entrez)NM_001146276 NM_001146277 NM_001146278 NM_020792
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)NCEH1
Cluster EST : UnigeneHs.444099 [ NCBI ]
CGAP (NCI)Hs.444099
Alternative Splicing GalleryENSG00000144959
Gene ExpressionNCEH1 [ NCBI-GEO ]   NCEH1 [ EBI - ARRAY_EXPRESS ]   NCEH1 [ SEEK ]   NCEH1 [ MEM ]
Gene Expression Viewer (FireBrowse)NCEH1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57552
GTEX Portal (Tissue expression)NCEH1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PIU2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PIU2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PIU2
Splice isoforms : SwissVarQ6PIU2
Catalytic activity : Enzyme3.1.1.- [ Enzyme-Expasy ]   3.1.1.-3.1.1.- [ IntEnz-EBI ]   3.1.1.- [ BRENDA ]   3.1.1.- [ KEGG ]   
PhosPhoSitePlusQ6PIU2
Domaine pattern : Prosite (Expaxy)LIPASE_GDXG_SER (PS01174)   
Domains : Interpro (EBI)AB_hydrolase    AB_hydrolase_3    Arylacetamide_deacetylase    Lipase_GDXG_put_SER_AS   
Domain families : Pfam (Sanger)Abhydrolase_3 (PF07859)   
Domain families : Pfam (NCBI)pfam07859   
Conserved Domain (NCBI)NCEH1
DMDM Disease mutations57552
Blocks (Seattle)NCEH1
SuperfamilyQ6PIU2
Human Protein AtlasENSG00000144959
Peptide AtlasQ6PIU2
HPRD07489
IPIIPI00790972   IPI00924788   IPI00002230   IPI00927596   
Protein Interaction databases
DIP (DOE-UCLA)Q6PIU2
IntAct (EBI)Q6PIU2
FunCoupENSG00000144959
BioGRIDNCEH1
STRING (EMBL)NCEH1
ZODIACNCEH1
Ontologies - Pathways
QuickGOQ6PIU2
Ontology : AmiGOsterol esterase activity  endoplasmic reticulum membrane  membrane  integral component of membrane  lipid catabolic process  
Ontology : EGO-EBIsterol esterase activity  endoplasmic reticulum membrane  membrane  integral component of membrane  lipid catabolic process  
Pathways : KEGGBile secretion   
NDEx NetworkNCEH1
Atlas of Cancer Signalling NetworkNCEH1
Wikipedia pathwaysNCEH1
Orthology - Evolution
OrthoDB57552
GeneTree (enSembl)ENSG00000144959
Phylogenetic Trees/Animal Genes : TreeFamNCEH1
HOVERGENQ6PIU2
HOGENOMQ6PIU2
Homologs : HomoloGeneNCEH1
Homology/Alignments : Family Browser (UCSC)NCEH1
Gene fusions - Rearrangements
Fusion : MitelmanGOLIM4/NCEH1 [3q26.2/3q26.31]  [t(3;3)(q26;q26)]  
Fusion : MitelmanGPR160/NCEH1 [3q26.2/3q26.31]  [t(3;3)(q26;q26)]  
Fusion : MitelmanIGF2BP2/NCEH1 [3q27.2/3q26.31]  [t(3;3)(q26;q27)]  
Fusion : MitelmanNCEH1/SPATA16 [3q26.31/3q26.31]  [t(3;3)(q26;q26)]  
Fusion: TCGAGOLIM4 3q26.2 NCEH1 3q26.31 LUAD
Fusion: TCGAIGF2BP2 3q27.2 NCEH1 3q26.31 BRCA
Fusion: TCGANCEH1 3q26.31 SPATA16 3q26.31 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNCEH1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NCEH1
dbVarNCEH1
ClinVarNCEH1
1000_GenomesNCEH1 
Exome Variant ServerNCEH1
ExAC (Exome Aggregation Consortium)NCEH1 (select the gene name)
Genetic variants : HAPMAP57552
Genomic Variants (DGV)NCEH1 [DGVbeta]
DECIPHER (Syndromes)3:172348435-172429008  ENSG00000144959
CONAN: Copy Number AnalysisNCEH1 
Mutations
ICGC Data PortalNCEH1 
TCGA Data PortalNCEH1 
Broad Tumor PortalNCEH1
OASIS PortalNCEH1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNCEH1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNCEH1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NCEH1
DgiDB (Drug Gene Interaction Database)NCEH1
DoCM (Curated mutations)NCEH1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NCEH1 (select a term)
intoGenNCEH1
Cancer3DNCEH1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613234   
Orphanet
MedgenNCEH1
Genetic Testing Registry NCEH1
NextProtQ6PIU2 [Medical]
TSGene57552
GENETestsNCEH1
Huge Navigator NCEH1 [HugePedia]
snp3D : Map Gene to Disease57552
BioCentury BCIQNCEH1
ClinGenNCEH1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57552
Chemical/Pharm GKB GenePA165697847
Clinical trialNCEH1
Miscellaneous
canSAR (ICR)NCEH1 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNCEH1
EVEXNCEH1
GoPubMedNCEH1
iHOPNCEH1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:18:19 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.