Atlas of Genetics and Cytogenetics in Oncology and Haematology


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NCF1 (neutrophil cytosolic factor 1)

Identity

Other namesNCF1A
NOXO2
SH3PXD1A
p47phox
HGNC (Hugo) NCF1
LocusID (NCBI) 653361
Atlas_Id 49878
Location 7q11.23
Location_base_pair Starts at 74188309 and ends at 74203720 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NCF1   7660
Cards
Entrez_Gene (NCBI)NCF1  653361  neutrophil cytosolic factor 1
GeneCards (Weizmann)NCF1
Ensembl hg19 (Hinxton)ENSG00000158517 [Gene_View]  chr7:74188309-74203720 [Contig_View]  NCF1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000158517 [Gene_View]  chr7:74188309-74203720 [Contig_View]  NCF1 [Vega]
ICGC DataPortalENSG00000158517
TCGA cBioPortalNCF1
AceView (NCBI)NCF1
Genatlas (Paris)NCF1
WikiGenes653361
SOURCE (Princeton)NCF1
Genomic and cartography
GoldenPath hg19 (UCSC)NCF1  -     chr7:74188309-74203720 +  7q11.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NCF1  -     7q11.23   [Description]    (hg38-Dec_2013)
EnsemblNCF1 - 7q11.23 [CytoView hg19]  NCF1 - 7q11.23 [CytoView hg38]
Mapping of homologs : NCBINCF1 [Mapview hg19]  NCF1 [Mapview hg38]
OMIM233700   608512   
Gene and transcription
Genbank (Entrez)AF330625 AF330626 AK127905 AK223217 AK292094
RefSeq transcript (Entrez)NM_000265
RefSeq genomic (Entrez)NC_000007 NC_018918 NG_009078 NT_007933 NW_004929332
Consensus coding sequences : CCDS (NCBI)NCF1
Cluster EST : UnigeneHs.655201 [ NCBI ]
CGAP (NCI)Hs.655201
Alternative Splicing : Fast-db (Paris)GSHG0027451
Alternative Splicing GalleryENSG00000158517
Gene ExpressionNCF1 [ NCBI-GEO ]   NCF1 [ EBI - ARRAY_EXPRESS ]   NCF1 [ SEEK ]   NCF1 [ MEM ]
Gene Expression Viewer (FireBrowse)NCF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)653361
Protein : pattern, domain, 3D structure
UniProt/SwissProtP14598 (Uniprot)
NextProtP14598  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP14598
Splice isoforms : SwissVarP14598 (Swissvar)
PhosPhoSitePlusP14598
Domaine pattern : Prosite (Expaxy)PX (PS50195)    SH3 (PS50002)   
Domains : Interpro (EBI)NADPH_oxidase_p47Phox_C    NECFESHC    P47PHOX    Phox    SH3_domain   
Domain families : Pfam (Sanger)NECFESHC (PF16621)    p47_phox_C (PF08944)    PX (PF00787)    SH3_1 (PF00018)   
Domain families : Pfam (NCBI)pfam16621    pfam08944    pfam00787    pfam00018   
Domain families : Smart (EMBL)PX (SM00312)  SH3 (SM00326)  
DMDM Disease mutations653361
Blocks (Seattle)NCF1
PDB (SRS)1GD5    1K4U    1KQ6    1NG2    1O7K    1OV3    1UEC    1W70    1WLP   
PDB (PDBSum)1GD5    1K4U    1KQ6    1NG2    1O7K    1OV3    1UEC    1W70    1WLP   
PDB (IMB)1GD5    1K4U    1KQ6    1NG2    1O7K    1OV3    1UEC    1W70    1WLP   
PDB (RSDB)1GD5    1K4U    1KQ6    1NG2    1O7K    1OV3    1UEC    1W70    1WLP   
Structural Biology KnowledgeBase1GD5    1K4U    1KQ6    1NG2    1O7K    1OV3    1UEC    1W70    1WLP   
SCOP (Structural Classification of Proteins)1GD5    1K4U    1KQ6    1NG2    1O7K    1OV3    1UEC    1W70    1WLP   
CATH (Classification of proteins structures)1GD5    1K4U    1KQ6    1NG2    1O7K    1OV3    1UEC    1W70    1WLP   
SuperfamilyP14598
Human Protein AtlasENSG00000158517
Peptide AtlasP14598
IPIIPI00788186   IPI00902858   IPI00924484   IPI01015820   IPI00927351   IPI00926936   
Protein Interaction databases
DIP (DOE-UCLA)P14598
IntAct (EBI)P14598
FunCoupENSG00000158517
BioGRIDNCF1
STRING (EMBL)NCF1
ZODIACNCF1
Ontologies - Pathways
QuickGOP14598
Ontology : AmiGOantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  protein binding  cytosol  cytosol  protein targeting to membrane  superoxide metabolic process  cellular defense response  electron carrier activity  superoxide-generating NADPH oxidase activity  SH3 domain binding  extrinsic component of membrane  phagolysosome  phosphatidylinositol binding  superoxide anion generation  superoxide anion generation  NADPH oxidase complex  NADPH oxidase complex  phosphatidylinositol-3,4-bisphosphate binding  innate immune response  cell redox homeostasis  respiratory burst  vascular endothelial growth factor receptor signaling pathway  oxidation-reduction process  oxidation-reduction process  
Ontology : EGO-EBIantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  protein binding  cytosol  cytosol  protein targeting to membrane  superoxide metabolic process  cellular defense response  electron carrier activity  superoxide-generating NADPH oxidase activity  SH3 domain binding  extrinsic component of membrane  phagolysosome  phosphatidylinositol binding  superoxide anion generation  superoxide anion generation  NADPH oxidase complex  NADPH oxidase complex  phosphatidylinositol-3,4-bisphosphate binding  innate immune response  cell redox homeostasis  respiratory burst  vascular endothelial growth factor receptor signaling pathway  oxidation-reduction process  oxidation-reduction process  
Pathways : BIOCARTAfMLP induced chemokine gene expression in HMC-1 cells [Genes]   
Pathways : KEGGChemokine signaling pathway    Phagosome    Osteoclast differentiation    Fc gamma R-mediated phagocytosis    Leukocyte transendothelial migration    Leishmaniasis   
NDEx Network
Atlas of Cancer Signalling NetworkNCF1
Wikipedia pathwaysNCF1
Orthology - Evolution
OrthoDB653361
GeneTree (enSembl)ENSG00000158517
Phylogenetic Trees/Animal Genes : TreeFamNCF1
Homologs : HomoloGeneNCF1
Homology/Alignments : Family Browser (UCSC)NCF1
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerNCF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NCF1
dbVarNCF1
ClinVarNCF1
1000_GenomesNCF1 
Exome Variant ServerNCF1
ExAC (Exome Aggregation Consortium)NCF1 (select the gene name)
SNP (GeneSNP Utah)NCF1
SNP : HGBaseNCF1
Genetic variants : HAPMAPNCF1
Genomic Variants (DGV)NCF1 [DGVbeta]
Mutations
ICGC Data PortalNCF1 
TCGA Data PortalNCF1 
Broad Tumor PortalNCF1
OASIS PortalNCF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNCF1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch NCF1
DgiDB (Drug Gene Interaction Database)NCF1
DoCM (Curated mutations)NCF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NCF1 (select a term)
intoGenNCF1
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)7:74188309-74203720
CONAN: Copy Number AnalysisNCF1 
Mutations and Diseases : HGMDNCF1
OMIM233700    608512   
MedgenNCF1
Genetic Testing Registry NCF1
NextProtP14598 [Medical]
TSGene653361
GENETestsNCF1
Huge Navigator NCF1 [HugePedia]  NCF1 [HugeCancerGEM]
snp3D : Map Gene to Disease653361
BioCentury BCIQNCF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD653361
Chemical/Pharm GKB GenePA31463
Clinical trialNCF1
Miscellaneous
canSAR (ICR)NCF1 (select the gene name)
Probes
Litterature
PubMed138 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNCF1
GoPubMedNCF1
iHOPNCF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Sat Apr 16 17:55:54 CEST 2016

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