Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NCOA5 (nuclear receptor coactivator 5)

Identity

Alias_symbol (synonym)bA465L10.6
CIA
Other alias
HGNC (Hugo) NCOA5
LocusID (NCBI) 57727
Atlas_Id 46988
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 46060987 and ends at 46089941 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARID4A (14q23.1) / NCOA5 (20q13.12)NCOA5 (20q13.12) / CDH4 (20q13.33)NCOA5 (20q13.12) / COPZ1 (12q13.13)
NCOA5 (20q13.12) / NCOA5 (20q13.12)NCOA5 (20q13.12) / PDGFC (4q32.1)SFTPB (2p11.2) / NCOA5 (20q13.12)
STX16 (20q13.32) / NCOA5 (20q13.12)NCOA5 20q13.12 / CDH4 20q13.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(9;20)(p13;q13) PAX5/NCOA5

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  NCOA5/CDH4 (20q13)
STX16/NCOA5 (20q13)

External links

Nomenclature
HGNC (Hugo)NCOA5   15909
Cards
Entrez_Gene (NCBI)NCOA5  57727  nuclear receptor coactivator 5
AliasesCIA; bA465L10.6
GeneCards (Weizmann)NCOA5
Ensembl hg19 (Hinxton)ENSG00000124160 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124160 [Gene_View]  ENSG00000124160 [Sequence]  chr20:46060987-46089941 [Contig_View]  NCOA5 [Vega]
ICGC DataPortalENSG00000124160
TCGA cBioPortalNCOA5
AceView (NCBI)NCOA5
Genatlas (Paris)NCOA5
WikiGenes57727
SOURCE (Princeton)NCOA5
Genetics Home Reference (NIH)NCOA5
Genomic and cartography
GoldenPath hg38 (UCSC)NCOA5  -     chr20:46060987-46089941 -  20q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NCOA5  -     20q13.12   [Description]    (hg19-Feb_2009)
NCOA5 - 20q13.12 [CytoView hg19]  NCOA5 - 20q13.12 [CytoView hg38]
Mapping of homologs : NCBINCOA5 [Mapview hg19]  NCOA5 [Mapview hg38]
OMIM616825   
Gene and transcription
Genbank (Entrez)AB046857 AF230533 AF470686 BC056872 BC140836
RefSeq transcript (Entrez)NM_001348148 NM_001348149 NM_001348150 NM_001348151 NM_020967
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NCOA5
Cluster EST : UnigeneHs.654991 [ NCBI ]
CGAP (NCI)Hs.654991
Alternative Splicing GalleryENSG00000124160
Gene ExpressionNCOA5 [ NCBI-GEO ]   NCOA5 [ EBI - ARRAY_EXPRESS ]   NCOA5 [ SEEK ]   NCOA5 [ MEM ]
Gene Expression Viewer (FireBrowse)NCOA5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57727
GTEX Portal (Tissue expression)NCOA5
Human Protein AtlasENSG00000124160-NCOA5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HCD5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HCD5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HCD5
Splice isoforms : SwissVarQ9HCD5
PhosPhoSitePlusQ9HCD5
Domains : Interpro (EBI)Anticodon-bd_dom_sf   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)NCOA5
DMDM Disease mutations57727
Blocks (Seattle)NCOA5
PDB (RSDB)1V95    2J7X    2J7Y    4ZI1   
PDB Europe1V95    2J7X    2J7Y    4ZI1   
PDB (PDBSum)1V95    2J7X    2J7Y    4ZI1   
PDB (IMB)1V95    2J7X    2J7Y    4ZI1   
Structural Biology KnowledgeBase1V95    2J7X    2J7Y    4ZI1   
SCOP (Structural Classification of Proteins)1V95    2J7X    2J7Y    4ZI1   
CATH (Classification of proteins structures)1V95    2J7X    2J7Y    4ZI1   
SuperfamilyQ9HCD5
Human Protein Atlas [tissue]ENSG00000124160-NCOA5 [tissue]
Peptide AtlasQ9HCD5
HPRD14813
IPIIPI00288941   IPI00647587   
Protein Interaction databases
DIP (DOE-UCLA)Q9HCD5
IntAct (EBI)Q9HCD5
FunCoupENSG00000124160
BioGRIDNCOA5
STRING (EMBL)NCOA5
ZODIACNCOA5
Ontologies - Pathways
QuickGOQ9HCD5
Ontology : AmiGOchromatin binding  RNA binding  protein binding  extracellular space  nucleus  actin cytoskeleton  glucose homeostasis  negative regulation of insulin receptor signaling pathway  
Ontology : EGO-EBIchromatin binding  RNA binding  protein binding  extracellular space  nucleus  actin cytoskeleton  glucose homeostasis  negative regulation of insulin receptor signaling pathway  
NDEx NetworkNCOA5
Atlas of Cancer Signalling NetworkNCOA5
Wikipedia pathwaysNCOA5
Orthology - Evolution
OrthoDB57727
GeneTree (enSembl)ENSG00000124160
Phylogenetic Trees/Animal Genes : TreeFamNCOA5
HOGENOMQ9HCD5
Homologs : HomoloGeneNCOA5
Homology/Alignments : Family Browser (UCSC)NCOA5
Gene fusions - Rearrangements
Fusion : MitelmanNCOA5/CDH4 [20q13.12/20q13.33]  
Fusion : MitelmanSTX16/NCOA5 [20q13.32/20q13.12]  [t(20;20)(q13;q13)]  
Fusion PortalNCOA5 20q13.12 CDH4 20q13.33 BRCA
Fusion Cancer (Beijing)SFTPB [2p11.2]  -  NCOA5 [20q13.12]  [FUSC003662]
Fusion : QuiverNCOA5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNCOA5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NCOA5
dbVarNCOA5
ClinVarNCOA5
1000_GenomesNCOA5 
Exome Variant ServerNCOA5
ExAC (Exome Aggregation Consortium)ENSG00000124160
GNOMAD BrowserENSG00000124160
Varsome BrowserNCOA5
Genetic variants : HAPMAP57727
Genomic Variants (DGV)NCOA5 [DGVbeta]
DECIPHERNCOA5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNCOA5 
Mutations
ICGC Data PortalNCOA5 
TCGA Data PortalNCOA5 
Broad Tumor PortalNCOA5
OASIS PortalNCOA5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNCOA5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNCOA5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NCOA5
DgiDB (Drug Gene Interaction Database)NCOA5
DoCM (Curated mutations)NCOA5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NCOA5 (select a term)
intoGenNCOA5
Cancer3DNCOA5(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616825   
Orphanet
DisGeNETNCOA5
MedgenNCOA5
Genetic Testing Registry NCOA5
NextProtQ9HCD5 [Medical]
TSGene57727
GENETestsNCOA5
Target ValidationNCOA5
Huge Navigator NCOA5 [HugePedia]
snp3D : Map Gene to Disease57727
BioCentury BCIQNCOA5
ClinGenNCOA5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57727
Chemical/Pharm GKB GenePA31474
Clinical trialNCOA5
Miscellaneous
canSAR (ICR)NCOA5 (select the gene name)
DataMed IndexNCOA5
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNCOA5
EVEXNCOA5
GoPubMedNCOA5
iHOPNCOA5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 21 15:59:28 CET 2019
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