Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NCOA5 (nuclear receptor coactivator 5)

Identity

Alias (NCBI)CIA
bA465L10.6
HGNC (Hugo) NCOA5
HGNC Alias symbbA465L10.6
CIA
HGNC Alias namecoactivator independent of AF-2
LocusID (NCBI) 57727
Atlas_Id 46988
Location 20q13.12  [Link to chromosome band 20q13]
Location_base_pair Starts at 46060995 and ends at 46089962 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARID4A (14q23.1) / NCOA5 (20q13.12)NCOA5 (20q13.12) / CDH4 (20q13.33)NCOA5 (20q13.12) / COPZ1 (12q13.13)
NCOA5 (20q13.12) / NCOA5 (20q13.12)NCOA5 (20q13.12) / PDGFC (4q32.1)SFTPB (2p11.2) / NCOA5 (20q13.12)
STX16 (20q13.32) / NCOA5 (20q13.12)NCOA5 20q13.12 / CDH4 20q13.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(9;20)(p13;q13) PAX5/NCOA5

External links

 

Nomenclature
HGNC (Hugo)NCOA5   15909
Cards
Entrez_Gene (NCBI)NCOA5    nuclear receptor coactivator 5
AliasesCIA; bA465L10.6
GeneCards (Weizmann)NCOA5
Ensembl hg19 (Hinxton)ENSG00000124160 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124160 [Gene_View]  ENSG00000124160 [Sequence]  chr20:46060995-46089962 [Contig_View]  NCOA5 [Vega]
ICGC DataPortalENSG00000124160
TCGA cBioPortalNCOA5
AceView (NCBI)NCOA5
Genatlas (Paris)NCOA5
SOURCE (Princeton)NCOA5
Genetics Home Reference (NIH)NCOA5
Genomic and cartography
GoldenPath hg38 (UCSC)NCOA5  -     chr20:46060995-46089962 -  20q13.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NCOA5  -     20q13.12   [Description]    (hg19-Feb_2009)
GoldenPathNCOA5 - 20q13.12 [CytoView hg19]  NCOA5 - 20q13.12 [CytoView hg38]
ImmunoBaseENSG00000124160
Genome Data Viewer NCBINCOA5 [Mapview hg19]  
OMIM616825   
Gene and transcription
Genbank (Entrez)AB046857 AF230533 AF470686 BC056872 BC140836
RefSeq transcript (Entrez)NM_001348148 NM_001348149 NM_001348150 NM_001348151 NM_020967
Consensus coding sequences : CCDS (NCBI)NCOA5
Gene ExpressionNCOA5 [ NCBI-GEO ]   NCOA5 [ EBI - ARRAY_EXPRESS ]   NCOA5 [ SEEK ]   NCOA5 [ MEM ]
Gene Expression Viewer (FireBrowse)NCOA5 [ Firebrowse - Broad ]
GenevisibleExpression of NCOA5 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57727
GTEX Portal (Tissue expression)NCOA5
Human Protein AtlasENSG00000124160-NCOA5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HCD5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HCD5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HCD5
PhosPhoSitePlusQ9HCD5
Domains : Interpro (EBI)Anticodon-bd_dom_sf   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)NCOA5
PDB (RSDB)1V95    2J7X    2J7Y    4ZI1   
PDB Europe1V95    2J7X    2J7Y    4ZI1   
PDB (PDBSum)1V95    2J7X    2J7Y    4ZI1   
PDB (IMB)1V95    2J7X    2J7Y    4ZI1   
Structural Biology KnowledgeBase1V95    2J7X    2J7Y    4ZI1   
SCOP (Structural Classification of Proteins)1V95    2J7X    2J7Y    4ZI1   
CATH (Classification of proteins structures)1V95    2J7X    2J7Y    4ZI1   
SuperfamilyQ9HCD5
AlphaFold pdb e-kbQ9HCD5   
Human Protein Atlas [tissue]ENSG00000124160-NCOA5 [tissue]
HPRD14813
Protein Interaction databases
DIP (DOE-UCLA)Q9HCD5
IntAct (EBI)Q9HCD5
BioGRIDNCOA5
STRING (EMBL)NCOA5
ZODIACNCOA5
Ontologies - Pathways
QuickGOQ9HCD5
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  chromatin binding  transcription corepressor activity  RNA binding  protein binding  extracellular space  nucleoplasm  actin cytoskeleton  glucose homeostasis  negative regulation of insulin receptor signaling pathway  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  chromatin binding  transcription corepressor activity  RNA binding  protein binding  extracellular space  nucleoplasm  actin cytoskeleton  glucose homeostasis  negative regulation of insulin receptor signaling pathway  
NDEx NetworkNCOA5
Atlas of Cancer Signalling NetworkNCOA5
Wikipedia pathwaysNCOA5
Orthology - Evolution
OrthoDB57727
GeneTree (enSembl)ENSG00000124160
Phylogenetic Trees/Animal Genes : TreeFamNCOA5
Homologs : HomoloGeneNCOA5
Homology/Alignments : Family Browser (UCSC)NCOA5
Gene fusions - Rearrangements
Fusion : MitelmanNCOA5/CDH4 [20q13.12/20q13.33]  
Fusion : MitelmanSTX16/NCOA5 [20q13.32/20q13.12]  
Fusion Cancer (Beijing)SFTPB [2p11.2]  -  NCOA5 [20q13.12]  [FUSC003662]
Fusion : QuiverNCOA5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNCOA5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NCOA5
dbVarNCOA5
ClinVarNCOA5
MonarchNCOA5
1000_GenomesNCOA5 
Exome Variant ServerNCOA5
GNOMAD BrowserENSG00000124160
Varsome BrowserNCOA5
ACMGNCOA5 variants
VarityQ9HCD5
Genomic Variants (DGV)NCOA5 [DGVbeta]
DECIPHERNCOA5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNCOA5 
Mutations
ICGC Data PortalNCOA5 
TCGA Data PortalNCOA5 
Broad Tumor PortalNCOA5
OASIS PortalNCOA5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNCOA5  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNCOA5
Mutations and Diseases : HGMDNCOA5
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNCOA5
DgiDB (Drug Gene Interaction Database)NCOA5
DoCM (Curated mutations)NCOA5
CIViC (Clinical Interpretations of Variants in Cancer)NCOA5
Cancer3DNCOA5
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616825   
Orphanet
DisGeNETNCOA5
MedgenNCOA5
Genetic Testing Registry NCOA5
NextProtQ9HCD5 [Medical]
GENETestsNCOA5
Target ValidationNCOA5
Huge Navigator NCOA5 [HugePedia]
ClinGenNCOA5
Clinical trials, drugs, therapy
MyCancerGenomeNCOA5
Protein Interactions : CTDNCOA5
Pharm GKB GenePA31474
PharosQ9HCD5
Clinical trialNCOA5
Miscellaneous
canSAR (ICR)NCOA5
HarmonizomeNCOA5
DataMed IndexNCOA5
Probes
Litterature
PubMed59 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNCOA5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:22:17 CEST 2021
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