Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NCR1 (natural cytotoxicity triggering receptor 1)

Identity

Alias (NCBI)CD335
LY94
NK-p46
NKP46
HGNC (Hugo) NCR1
HGNC Alias symbNK-p46
NKP46
CD335
HGNC Previous nameLY94
HGNC Previous namelymphocyte antigen 94 (mouse) homolog (activating NK-receptor; NK-p46)
LocusID (NCBI) 9437
Atlas_Id 45588
Location 19q13.42  [Link to chromosome band 19q13]
Location_base_pair Starts at 54906148 and ends at 54913073 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NCR1 (19q13.42) / FBXO18 (10p15.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NCR1   6731
Cards
Entrez_Gene (NCBI)NCR1    natural cytotoxicity triggering receptor 1
AliasesCD335; LY94; NK-p46; NKP46
GeneCards (Weizmann)NCR1
Ensembl hg19 (Hinxton)ENSG00000189430 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000189430 [Gene_View]  ENSG00000189430 [Sequence]  chr19:54906148-54913073 [Contig_View]  NCR1 [Vega]
ICGC DataPortalENSG00000189430
TCGA cBioPortalNCR1
AceView (NCBI)NCR1
Genatlas (Paris)NCR1
SOURCE (Princeton)NCR1
Genetics Home Reference (NIH)NCR1
Genomic and cartography
GoldenPath hg38 (UCSC)NCR1  -     chr19:54906148-54913073 +  19q13.42   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NCR1  -     19q13.42   [Description]    (hg19-Feb_2009)
GoldenPathNCR1 - 19q13.42 [CytoView hg19]  NCR1 - 19q13.42 [CytoView hg38]
ImmunoBaseENSG00000189430
genome Data Viewer NCBINCR1 [Mapview hg19]  
OMIM604530   
Gene and transcription
Genbank (Entrez)AJ001383 AJ006121 AJ006122 AJ006123 AY346373
RefSeq transcript (Entrez)NM_001145457 NM_001145458 NM_001242356 NM_001242357 NM_004829
RefSeq genomic (Entrez)NC_000019 NT_187671 NT_187674 NT_187675 NT_187676 NT_187677 NT_187683 NT_187693 NW_003571054 NW_003571055 NW_003571056 NW_003571057 NW_003571058 NW_003571059 NW_003571060 NW_003571061 NW_016107304 NW_016107312
Consensus coding sequences : CCDS (NCBI)NCR1
Alternative Splicing GalleryENSG00000189430
Gene ExpressionNCR1 [ NCBI-GEO ]   NCR1 [ EBI - ARRAY_EXPRESS ]   NCR1 [ SEEK ]   NCR1 [ MEM ]
Gene Expression Viewer (FireBrowse)NCR1 [ Firebrowse - Broad ]
GenevisibleExpression of NCR1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9437
GTEX Portal (Tissue expression)NCR1
Human Protein AtlasENSG00000189430-NCR1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO76036   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO76036  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO76036
Splice isoforms : SwissVarO76036
PhosPhoSitePlusO76036
Domains : Interpro (EBI)Ig-like_dom_sf    Ig-like_fold    Ig_sub   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)NCR1
Blocks (Seattle)NCR1
PDB (RSDB)1OLL    1P6F    6IAP   
PDB Europe1OLL    1P6F    6IAP   
PDB (PDBSum)1OLL    1P6F    6IAP   
PDB (IMB)1OLL    1P6F    6IAP   
Structural Biology KnowledgeBase1OLL    1P6F    6IAP   
SCOP (Structural Classification of Proteins)1OLL    1P6F    6IAP   
CATH (Classification of proteins structures)1OLL    1P6F    6IAP   
SuperfamilyO76036
Human Protein Atlas [tissue]ENSG00000189430-NCR1 [tissue]
Peptide AtlasO76036
HPRD05167
IPIIPI00006749   IPI00411991   IPI00008296   IPI00411994   IPI00411995   IPI00940953   IPI00893376   IPI01015544   
Protein Interaction databases
DIP (DOE-UCLA)O76036
IntAct (EBI)O76036
BioGRIDNCR1
STRING (EMBL)NCR1
ZODIACNCR1
Ontologies - Pathways
QuickGOO76036
Ontology : AmiGOprotein binding  plasma membrane  integral component of plasma membrane  cellular defense response  signal transduction  SWI/SNF complex  natural killer cell activation  regulation of natural killer cell mediated cytotoxicity  regulation of immune response  
Ontology : EGO-EBIprotein binding  plasma membrane  integral component of plasma membrane  cellular defense response  signal transduction  SWI/SNF complex  natural killer cell activation  regulation of natural killer cell mediated cytotoxicity  regulation of immune response  
Pathways : KEGGNatural killer cell mediated cytotoxicity   
NDEx NetworkNCR1
Atlas of Cancer Signalling NetworkNCR1
Wikipedia pathwaysNCR1
Orthology - Evolution
OrthoDB9437
GeneTree (enSembl)ENSG00000189430
Phylogenetic Trees/Animal Genes : TreeFamNCR1
HOGENOMO76036
Homologs : HomoloGeneNCR1
Homology/Alignments : Family Browser (UCSC)NCR1
Gene fusions - Rearrangements
Fusion : QuiverNCR1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNCR1 [hg38]
dbVarNCR1
ClinVarNCR1
MonarchNCR1
1000_GenomesNCR1 
Exome Variant ServerNCR1
GNOMAD BrowserENSG00000189430
Varsome BrowserNCR1
Genomic Variants (DGV)NCR1 [DGVbeta]
DECIPHERNCR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNCR1 
Mutations
ICGC Data PortalNCR1 
TCGA Data PortalNCR1 
Broad Tumor PortalNCR1
OASIS PortalNCR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNCR1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNCR1
Mutations and Diseases : HGMDNCR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NCR1
DgiDB (Drug Gene Interaction Database)NCR1
DoCM (Curated mutations)NCR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NCR1 (select a term)
intoGenNCR1
Cancer3DNCR1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604530   
Orphanet
DisGeNETNCR1
MedgenNCR1
Genetic Testing Registry NCR1
NextProtO76036 [Medical]
GENETestsNCR1
Target ValidationNCR1
Huge Navigator NCR1 [HugePedia]
ClinGenNCR1
Clinical trials, drugs, therapy
MyCancerGenomeNCR1
Protein Interactions : CTD
Pharm GKB GenePA30495
PharosO76036
Clinical trialNCR1
Miscellaneous
canSAR (ICR)NCR1 (select the gene name)
HarmonizomeNCR1
DataMed IndexNCR1
Probes
Litterature
PubMed85 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNCR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jan 1 18:28:26 CET 2021
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