NCR3LG1 (natural killer cell cytotoxicity receptor 3 ligand 1)

2011-05-01  

Identity

HGNC
LOCATION
11p15.1
LOCUSID
ALIAS
B7-H6,B7H6,DKFZp686O24166

Other Information

Locus ID:

NCBI: 374383
MIM: 613714
HGNC: 42400
Ensembl: ENSG00000188211

Variants:

dbSNP: 374383
ClinVar: 374383
TCGA: ENSG00000188211
COSMIC: NCR3LG1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000188211ENST00000338965Q68D85
ENSG00000188211ENST00000530403Q68D85

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366928442023B7-H6 enhances F-actin rearrangement by targeting c-MYC activation to promote medulloblastoma migration and invasion.0
370530792023B7H6 silencing increases chemosensitivity to dacarbazine and suppresses cell survival and migration in cutaneous melanoma.1
366928442023B7-H6 enhances F-actin rearrangement by targeting c-MYC activation to promote medulloblastoma migration and invasion.0
370530792023B7H6 silencing increases chemosensitivity to dacarbazine and suppresses cell survival and migration in cutaneous melanoma.1
332200982021Dual role of B7-H6 as a novel prognostic marker in hepatocellular carcinoma.4
334834212021Large remodeling of the Myc-induced cell surface proteome in B cells and prostate cells creates new opportunities for immunotherapy.8
335237152021NCR3LG1 (B7-H6) is a potential prognostic factor for bladder cancer patients.2
336718362021Secreted Ligands of the NK Cell Receptor NKp30: B7-H6 Is in Contrast to BAG6 Only Marginally Released via Extracellular Vesicles.7
338243672021Immune checkpoint molecules B7-H6 and PD-L1 co-pattern the tumor inflammatory microenvironment in human breast cancer.7
342800082021B7-H6 as a Diagnostic Biomarker for Cervical Squamous Cell Carcinoma.1
332200982021Dual role of B7-H6 as a novel prognostic marker in hepatocellular carcinoma.4
334834212021Large remodeling of the Myc-induced cell surface proteome in B cells and prostate cells creates new opportunities for immunotherapy.8
335237152021NCR3LG1 (B7-H6) is a potential prognostic factor for bladder cancer patients.2
336718362021Secreted Ligands of the NK Cell Receptor NKp30: B7-H6 Is in Contrast to BAG6 Only Marginally Released via Extracellular Vesicles.7
338243672021Immune checkpoint molecules B7-H6 and PD-L1 co-pattern the tumor inflammatory microenvironment in human breast cancer.7

Citation

Dessen P

NCR3LG1 (natural killer cell cytotoxicity receptor 3 ligand 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-05-01

Online version: http://atlasgeneticsoncology.org/gene/52208/ncr3lg1