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NCS1 (neuronal calcium sensor 1)

Identity

Alias_namesFREQ
frequenin (Drosophila) homolog
frequenin homolog (Drosophila)
Alias_symbol (synonym)NCS-1
Other aliasFLUP
HGNC (Hugo) NCS1
LocusID (NCBI) 23413
Atlas_Id 70745
Location 9q34.11  [Link to chromosome band 9q34]
Location_base_pair Starts at 130200593 and ends at 130237304 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ASS1 (9q34.11) / NCS1 (9q34.11)NCS1 (9q34.11) / NCS1 (9q34.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NCS1   3953
Cards
Entrez_Gene (NCBI)NCS1  23413  neuronal calcium sensor 1
AliasesFLUP; FREQ
GeneCards (Weizmann)NCS1
Ensembl hg19 (Hinxton)ENSG00000107130 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000107130 [Gene_View]  chr9:130200593-130237304 [Contig_View]  NCS1 [Vega]
ICGC DataPortalENSG00000107130
TCGA cBioPortalNCS1
AceView (NCBI)NCS1
Genatlas (Paris)NCS1
WikiGenes23413
SOURCE (Princeton)NCS1
Genetics Home Reference (NIH)NCS1
Genomic and cartography
GoldenPath hg38 (UCSC)NCS1  -     chr9:130200593-130237304 +  9q34.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NCS1  -     9q34.11   [Description]    (hg19-Feb_2009)
EnsemblNCS1 - 9q34.11 [CytoView hg19]  NCS1 - 9q34.11 [CytoView hg38]
Mapping of homologs : NCBINCS1 [Mapview hg19]  NCS1 [Mapview hg38]
OMIM603315   
Gene and transcription
Genbank (Entrez)AF134479 AF186409 AI521726 AI564128 AI768193
RefSeq transcript (Entrez)NM_001128826 NM_014286
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NCS1
Cluster EST : UnigeneHs.714951 [ NCBI ]
CGAP (NCI)Hs.714951
Alternative Splicing GalleryENSG00000107130
Gene ExpressionNCS1 [ NCBI-GEO ]   NCS1 [ EBI - ARRAY_EXPRESS ]   NCS1 [ SEEK ]   NCS1 [ MEM ]
Gene Expression Viewer (FireBrowse)NCS1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23413
GTEX Portal (Tissue expression)NCS1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62166   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62166  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62166
Splice isoforms : SwissVarP62166
PhosPhoSitePlusP62166
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom   
Domain families : Pfam (Sanger)EF-hand_1 (PF00036)    EF-hand_7 (PF13499)   
Domain families : Pfam (NCBI)pfam00036    pfam13499   
Domain families : Smart (EMBL)EFh (SM00054)  
Conserved Domain (NCBI)NCS1
DMDM Disease mutations23413
Blocks (Seattle)NCS1
PDB (SRS)1G8I    2LCP    4GUK   
PDB (PDBSum)1G8I    2LCP    4GUK   
PDB (IMB)1G8I    2LCP    4GUK   
PDB (RSDB)1G8I    2LCP    4GUK   
Structural Biology KnowledgeBase1G8I    2LCP    4GUK   
SCOP (Structural Classification of Proteins)1G8I    2LCP    4GUK   
CATH (Classification of proteins structures)1G8I    2LCP    4GUK   
SuperfamilyP62166
Human Protein AtlasENSG00000107130
Peptide AtlasP62166
HPRD04500
IPIIPI00219110   IPI00900321   
Protein Interaction databases
DIP (DOE-UCLA)P62166
IntAct (EBI)P62166
FunCoupENSG00000107130
BioGRIDNCS1
STRING (EMBL)NCS1
ZODIACNCS1
Ontologies - Pathways
QuickGOP62166
Ontology : AmiGOmagnesium ion binding  voltage-gated calcium channel activity  calcium ion binding  protein binding  cytoplasm  Golgi apparatus  cytosol  plasma membrane  regulation of neuron projection development  postsynaptic density  protein kinase binding  cell junction  axon  dendrite  dense core granule  intracellular membrane-bounded organelle  postsynaptic membrane  positive regulation of exocytosis  phosphatidylinositol-mediated signaling  perinuclear region of cytoplasm  extracellular exosome  calcium ion transmembrane transport  
Ontology : EGO-EBImagnesium ion binding  voltage-gated calcium channel activity  calcium ion binding  protein binding  cytoplasm  Golgi apparatus  cytosol  plasma membrane  regulation of neuron projection development  postsynaptic density  protein kinase binding  cell junction  axon  dendrite  dense core granule  intracellular membrane-bounded organelle  postsynaptic membrane  positive regulation of exocytosis  phosphatidylinositol-mediated signaling  perinuclear region of cytoplasm  extracellular exosome  calcium ion transmembrane transport  
NDEx NetworkNCS1
Atlas of Cancer Signalling NetworkNCS1
Wikipedia pathwaysNCS1
Orthology - Evolution
OrthoDB23413
GeneTree (enSembl)ENSG00000107130
Phylogenetic Trees/Animal Genes : TreeFamNCS1
HOVERGENP62166
HOGENOMP62166
Homologs : HomoloGeneNCS1
Homology/Alignments : Family Browser (UCSC)NCS1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNCS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NCS1
dbVarNCS1
ClinVarNCS1
1000_GenomesNCS1 
Exome Variant ServerNCS1
ExAC (Exome Aggregation Consortium)NCS1 (select the gene name)
Genetic variants : HAPMAP23413
Genomic Variants (DGV)NCS1 [DGVbeta]
DECIPHERNCS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNCS1 
Mutations
ICGC Data PortalNCS1 
TCGA Data PortalNCS1 
Broad Tumor PortalNCS1
OASIS PortalNCS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNCS1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNCS1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NCS1
DgiDB (Drug Gene Interaction Database)NCS1
DoCM (Curated mutations)NCS1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NCS1 (select a term)
intoGenNCS1
Cancer3DNCS1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603315   
Orphanet
MedgenNCS1
Genetic Testing Registry NCS1
NextProtP62166 [Medical]
TSGene23413
GENETestsNCS1
Target ValidationNCS1
Huge Navigator NCS1 [HugePedia]
snp3D : Map Gene to Disease23413
BioCentury BCIQNCS1
ClinGenNCS1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23413
Chemical/Pharm GKB GenePA28371
Clinical trialNCS1
Miscellaneous
canSAR (ICR)NCS1 (select the gene name)
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNCS1
EVEXNCS1
GoPubMedNCS1
iHOPNCS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:32:23 CEST 2017

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