Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23385
MIM: 605254
HGNC: 17091
Ensembl: ENSG00000162736
Variants:
dbSNP: 23385
ClinVar: 23385
TCGA: ENSG00000162736
COSMIC: NCSTN
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37490873 | 2024 | Discovery and Potential Functional Characterization of Long Noncoding RNAs Associated with Familial Acne Inversa with NCSTN Mutation. | 1 |
| 37490873 | 2024 | Discovery and Potential Functional Characterization of Long Noncoding RNAs Associated with Familial Acne Inversa with NCSTN Mutation. | 1 |
| 37665193 | 2023 | A loss-of-function NCSTN mutation associated with familial Dowling Degos disease and hidradenitis suppurativa. | 1 |
| 37665193 | 2023 | A loss-of-function NCSTN mutation associated with familial Dowling Degos disease and hidradenitis suppurativa. | 1 |
| 34860362 | 2022 | A novel mutation of the NCSTN gene in a Chinese hidradenitis suppurativa family with familial comedones as the main clinical manifestation. | 2 |
| 35016821 | 2022 | Evolutionary distinct roles of γ-secretase subunit nicastrin in zebrafish and humans. | 1 |
| 34860362 | 2022 | A novel mutation of the NCSTN gene in a Chinese hidradenitis suppurativa family with familial comedones as the main clinical manifestation. | 2 |
| 35016821 | 2022 | Evolutionary distinct roles of γ-secretase subunit nicastrin in zebrafish and humans. | 1 |
| 33460495 | 2021 | Genetic variations in gamma-secretase and PSTPIP1 in hidradenitis suppurativa in Singaporean Chinese. | 0 |
| 33460495 | 2021 | Genetic variations in gamma-secretase and PSTPIP1 in hidradenitis suppurativa in Singaporean Chinese. | 0 |
| 32631394 | 2020 | NCSTN promotes hepatocellular carcinoma cell growth and metastasis via β-catenin activation in a Notch1/AKT dependent manner. | 14 |
| 32940366 | 2020 | Two novel nicastrin mutations in Chinese families with acne inversa. | 2 |
| 32631394 | 2020 | NCSTN promotes hepatocellular carcinoma cell growth and metastasis via β-catenin activation in a Notch1/AKT dependent manner. | 14 |
| 32940366 | 2020 | Two novel nicastrin mutations in Chinese families with acne inversa. | 2 |
| 30120935 | 2019 | Nicastrin/miR-30a-3p/RAB31 Axis Regulates Keratinocyte Differentiation by Impairing EGFR Signaling in Familial Acne Inversa. | 16 |
Citation
Dessen P
NCSTN (nicastrin)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46883/ncstn
