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NDC1 (NDC1 transmembrane nucleoporin)

Identity

Alias (NCBI)NET3
TMEM48
HGNC (Hugo) NDC1
HGNC Alias symbFLJ10407
NET3
HGNC Alias namenuclear division cycle 1 homolog (S. cerevisiae)
HGNC Previous nameTMEM48
HGNC Previous nametransmembrane protein 48
LocusID (NCBI) 55706
Atlas_Id 57939
Location 1p32.3  [Link to chromosome band 1p32]
Location_base_pair Starts at 53765481 and ends at 53838296 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CXCL8 (4q13.3) / NDC1 (1p32.3)SAR1A (10q22.1) / NDC1 (1p32.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(1;21)(p32;q22) RUNX1/NDC1


External links

 

Nomenclature
HGNC (Hugo)NDC1   25525
Cards
Entrez_Gene (NCBI)NDC1    NDC1 transmembrane nucleoporin
AliasesNET3; TMEM48
GeneCards (Weizmann)NDC1
Ensembl hg19 (Hinxton)ENSG00000058804 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000058804 [Gene_View]  ENSG00000058804 [Sequence]  chr1:53765481-53838296 [Contig_View]  NDC1 [Vega]
ICGC DataPortalENSG00000058804
TCGA cBioPortalNDC1
AceView (NCBI)NDC1
Genatlas (Paris)NDC1
SOURCE (Princeton)NDC1
Genetics Home Reference (NIH)NDC1
Genomic and cartography
GoldenPath hg38 (UCSC)NDC1  -     chr1:53765481-53838296 -  1p32.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NDC1  -     1p32.3   [Description]    (hg19-Feb_2009)
GoldenPathNDC1 - 1p32.3 [CytoView hg19]  NDC1 - 1p32.3 [CytoView hg38]
ImmunoBaseENSG00000058804
Genome Data Viewer NCBINDC1 [Mapview hg19]  
OMIM610115   
Gene and transcription
Genbank (Entrez)AK001269 AK001593 AK022618 AK025450 AK091439
RefSeq transcript (Entrez)NM_001168551 NM_018087
Consensus coding sequences : CCDS (NCBI)NDC1
Gene ExpressionNDC1 [ NCBI-GEO ]   NDC1 [ EBI - ARRAY_EXPRESS ]   NDC1 [ SEEK ]   NDC1 [ MEM ]
Gene Expression Viewer (FireBrowse)NDC1 [ Firebrowse - Broad ]
GenevisibleExpression of NDC1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55706
GTEX Portal (Tissue expression)NDC1
Human Protein AtlasENSG00000058804-NDC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BTX1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BTX1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BTX1
PhosPhoSitePlusQ9BTX1
Domains : Interpro (EBI)Nucleoporin_prot_Ndc1/Nup   
Domain families : Pfam (Sanger)Ndc1_Nup (PF09531)   
Domain families : Pfam (NCBI)pfam09531   
Conserved Domain (NCBI)NDC1
SuperfamilyQ9BTX1
AlphaFold pdb e-kbQ9BTX1   
Human Protein Atlas [tissue]ENSG00000058804-NDC1 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9BTX1
IntAct (EBI)Q9BTX1
BioGRIDNDC1
STRING (EMBL)NDC1
ZODIACNDC1
Ontologies - Pathways
QuickGOQ9BTX1
Ontology : AmiGOnuclear envelope  nuclear pore  cytoplasm  plasma membrane  regulation of glycolytic process  mRNA export from nucleus  tRNA export from nucleus  nuclear pore organization  mitotic nuclear membrane reassembly  homologous chromosome pairing at meiosis  spermatogenesis  protein transport  actin cytoskeleton  membrane  integral component of membrane  viral process  protein sumoylation  structural constituent of nuclear pore  viral life cycle  viral transcription  protein-macromolecule adaptor activity  nuclear membrane  host cell  nuclear pore complex assembly  nuclear pore localization  regulation of gene silencing by miRNA  nuclear pore transmembrane ring  intracellular transport of virus  regulation of cellular response to heat  
Ontology : EGO-EBInuclear envelope  nuclear pore  cytoplasm  plasma membrane  regulation of glycolytic process  mRNA export from nucleus  tRNA export from nucleus  nuclear pore organization  mitotic nuclear membrane reassembly  homologous chromosome pairing at meiosis  spermatogenesis  protein transport  actin cytoskeleton  membrane  integral component of membrane  viral process  protein sumoylation  structural constituent of nuclear pore  viral life cycle  viral transcription  protein-macromolecule adaptor activity  nuclear membrane  host cell  nuclear pore complex assembly  nuclear pore localization  regulation of gene silencing by miRNA  nuclear pore transmembrane ring  intracellular transport of virus  regulation of cellular response to heat  
Pathways : KEGGRNA transport   
NDEx NetworkNDC1
Atlas of Cancer Signalling NetworkNDC1
Wikipedia pathwaysNDC1
Orthology - Evolution
OrthoDB55706
GeneTree (enSembl)ENSG00000058804
Phylogenetic Trees/Animal Genes : TreeFamNDC1
Homologs : HomoloGeneNDC1
Homology/Alignments : Family Browser (UCSC)NDC1
Gene fusions - Rearrangements
Fusion : QuiverNDC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNDC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NDC1
dbVarNDC1
ClinVarNDC1
MonarchNDC1
1000_GenomesNDC1 
Exome Variant ServerNDC1
GNOMAD BrowserENSG00000058804
Varsome BrowserNDC1
ACMGNDC1 variants
VarityQ9BTX1
Genomic Variants (DGV)NDC1 [DGVbeta]
DECIPHERNDC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNDC1 
Mutations
ICGC Data PortalNDC1 
TCGA Data PortalNDC1 
Broad Tumor PortalNDC1
OASIS PortalNDC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNDC1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNDC1
Mutations and Diseases : HGMDNDC1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNDC1
DgiDB (Drug Gene Interaction Database)NDC1
DoCM (Curated mutations)NDC1
CIViC (Clinical Interpretations of Variants in Cancer)NDC1
Cancer3DNDC1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610115   
Orphanet
DisGeNETNDC1
MedgenNDC1
Genetic Testing Registry NDC1
NextProtQ9BTX1 [Medical]
GENETestsNDC1
Target ValidationNDC1
Huge Navigator NDC1 [HugePedia]
ClinGenNDC1
Clinical trials, drugs, therapy
MyCancerGenomeNDC1
Protein Interactions : CTDNDC1
Pharm GKB GenePA142670764
PharosQ9BTX1
Clinical trialNDC1
Miscellaneous
canSAR (ICR)NDC1
HarmonizomeNDC1
DataMed IndexNDC1
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNDC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:22:20 CEST 2021

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