Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NDFIP1 (Nedd4 family interacting protein 1)

Identity

Alias (NCBI)N4WBP5
HGNC (Hugo) NDFIP1
HGNC Alias symbN4WBP5
MGC10924
LocusID (NCBI) 80762
Atlas_Id 56091
Location 5q31.3  [Link to chromosome band 5q31]
Location_base_pair Starts at 142108779 and ends at 142154440 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DIAPH1 (5q31.3) / NDFIP1 (5q31.3)LOC100507412 (-) / NDFIP1 (5q31.3)NDFIP1 (5q31.3) / NDFIP1 (5q31.3)
NDFIP1 (5q31.3) / NDUFAF2 (5q12.1)NDFIP1 (5q31.3) / SIK3 (11q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)NDFIP1   17592
Cards
Entrez_Gene (NCBI)NDFIP1    Nedd4 family interacting protein 1
AliasesN4WBP5
GeneCards (Weizmann)NDFIP1
Ensembl hg19 (Hinxton)ENSG00000131507 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131507 [Gene_View]  ENSG00000131507 [Sequence]  chr5:142108779-142154440 [Contig_View]  NDFIP1 [Vega]
ICGC DataPortalENSG00000131507
TCGA cBioPortalNDFIP1
AceView (NCBI)NDFIP1
Genatlas (Paris)NDFIP1
SOURCE (Princeton)NDFIP1
Genetics Home Reference (NIH)NDFIP1
Genomic and cartography
GoldenPath hg38 (UCSC)NDFIP1  -     chr5:142108779-142154440 +  5q31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NDFIP1  -     5q31.3   [Description]    (hg19-Feb_2009)
GoldenPathNDFIP1 - 5q31.3 [CytoView hg19]  NDFIP1 - 5q31.3 [CytoView hg38]
ImmunoBaseENSG00000131507
Genome Data Viewer NCBINDFIP1 [Mapview hg19]  
OMIM612050   
Gene and transcription
Genbank (Entrez)AA496123 AB097010 AB097037 AI929639 AK075495
RefSeq transcript (Entrez)NM_030571
Consensus coding sequences : CCDS (NCBI)NDFIP1
Gene ExpressionNDFIP1 [ NCBI-GEO ]   NDFIP1 [ EBI - ARRAY_EXPRESS ]   NDFIP1 [ SEEK ]   NDFIP1 [ MEM ]
Gene Expression Viewer (FireBrowse)NDFIP1 [ Firebrowse - Broad ]
GenevisibleExpression of NDFIP1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80762
GTEX Portal (Tissue expression)NDFIP1
Human Protein AtlasENSG00000131507-NDFIP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BT67   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BT67  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BT67
PhosPhoSitePlusQ9BT67
Domains : Interpro (EBI)NEDD4/Bsd2   
Domain families : Pfam (Sanger)DUF2370 (PF10176)   
Domain families : Pfam (NCBI)pfam10176   
Conserved Domain (NCBI)NDFIP1
SuperfamilyQ9BT67
AlphaFold pdb e-kbQ9BT67   
Human Protein Atlas [tissue]ENSG00000131507-NDFIP1 [tissue]
HPRD14816
Protein Interaction databases
DIP (DOE-UCLA)Q9BT67
IntAct (EBI)Q9BT67
BioGRIDNDFIP1
STRING (EMBL)NDFIP1
ZODIACNDFIP1
Ontologies - Pathways
QuickGOQ9BT67
Ontology : AmiGOGolgi membrane  regulation of myeloid leukocyte differentiation  negative regulation of type 2 immune response  protein binding  extracellular region  endoplasmic reticulum  Golgi apparatus  cell cortex  ubiquitin-dependent protein catabolic process  cellular iron ion homeostasis  vacuolar transport  endosome membrane  negative regulation of gene expression  integral component of membrane  metal ion transport  dendrite  positive regulation of protein ubiquitination  positive regulation of protein ubiquitination  positive regulation of protein ubiquitination  negative regulation of transporter activity  negative regulation of interleukin-4 production  negative regulation of T cell proliferation  positive regulation of I-kappaB kinase/NF-kappaB signaling  synapse  regulation of lymphocyte differentiation  positive regulation of protein catabolic process  negative regulation of isotype switching to IgE isotypes  regulation of isotype switching to IgG isotypes  perinuclear region of cytoplasm  perinuclear region of cytoplasm  WW domain binding  negative regulation of inflammatory response  negative regulation of protein transport  
Ontology : EGO-EBIGolgi membrane  regulation of myeloid leukocyte differentiation  negative regulation of type 2 immune response  protein binding  extracellular region  endoplasmic reticulum  Golgi apparatus  cell cortex  ubiquitin-dependent protein catabolic process  cellular iron ion homeostasis  vacuolar transport  endosome membrane  negative regulation of gene expression  integral component of membrane  metal ion transport  dendrite  positive regulation of protein ubiquitination  positive regulation of protein ubiquitination  positive regulation of protein ubiquitination  negative regulation of transporter activity  negative regulation of interleukin-4 production  negative regulation of T cell proliferation  positive regulation of I-kappaB kinase/NF-kappaB signaling  synapse  regulation of lymphocyte differentiation  positive regulation of protein catabolic process  negative regulation of isotype switching to IgE isotypes  regulation of isotype switching to IgG isotypes  perinuclear region of cytoplasm  perinuclear region of cytoplasm  WW domain binding  negative regulation of inflammatory response  negative regulation of protein transport  
NDEx NetworkNDFIP1
Atlas of Cancer Signalling NetworkNDFIP1
Wikipedia pathwaysNDFIP1
Orthology - Evolution
OrthoDB80762
GeneTree (enSembl)ENSG00000131507
Phylogenetic Trees/Animal Genes : TreeFamNDFIP1
Homologs : HomoloGeneNDFIP1
Homology/Alignments : Family Browser (UCSC)NDFIP1
Gene fusions - Rearrangements
Fusion : QuiverNDFIP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNDFIP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NDFIP1
dbVarNDFIP1
ClinVarNDFIP1
MonarchNDFIP1
1000_GenomesNDFIP1 
Exome Variant ServerNDFIP1
GNOMAD BrowserENSG00000131507
Varsome BrowserNDFIP1
ACMGNDFIP1 variants
VarityQ9BT67
Genomic Variants (DGV)NDFIP1 [DGVbeta]
DECIPHERNDFIP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNDFIP1 
Mutations
ICGC Data PortalNDFIP1 
TCGA Data PortalNDFIP1 
Broad Tumor PortalNDFIP1
OASIS PortalNDFIP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNDFIP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNDFIP1
Mutations and Diseases : HGMDNDFIP1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaNDFIP1
DgiDB (Drug Gene Interaction Database)NDFIP1
DoCM (Curated mutations)NDFIP1
CIViC (Clinical Interpretations of Variants in Cancer)NDFIP1
Cancer3DNDFIP1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612050   
Orphanet
DisGeNETNDFIP1
MedgenNDFIP1
Genetic Testing Registry NDFIP1
NextProtQ9BT67 [Medical]
GENETestsNDFIP1
Target ValidationNDFIP1
Huge Navigator NDFIP1 [HugePedia]
ClinGenNDFIP1
Clinical trials, drugs, therapy
MyCancerGenomeNDFIP1
Protein Interactions : CTDNDFIP1
Pharm GKB GenePA134943402
PharosQ9BT67
Clinical trialNDFIP1
Miscellaneous
canSAR (ICR)NDFIP1
HarmonizomeNDFIP1
DataMed IndexNDFIP1
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNDFIP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:22:21 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.