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NDFIP1 (Nedd4 family interacting protein 1)

Identity

Alias_symbol (synonym)N4WBP5
MGC10924
Other alias
HGNC (Hugo) NDFIP1
LocusID (NCBI) 80762
Atlas_Id 56091
Location 5q31.3  [Link to chromosome band 5q31]
Location_base_pair Starts at 141488324 and ends at 141534008 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DIAPH1 (5q31.3) / NDFIP1 (5q31.3)LOC100507412 (-) / NDFIP1 (5q31.3)NDFIP1 (5q31.3) / NDFIP1 (5q31.3)
NDFIP1 (5q31.3) / NDUFAF2 (5q12.1)NDFIP1 (5q31.3) / SIK3 (11q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NDFIP1   17592
Cards
Entrez_Gene (NCBI)NDFIP1  80762  Nedd4 family interacting protein 1
AliasesN4WBP5
GeneCards (Weizmann)NDFIP1
Ensembl hg19 (Hinxton)ENSG00000131507 [Gene_View]  chr5:141488324-141534008 [Contig_View]  NDFIP1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000131507 [Gene_View]  chr5:141488324-141534008 [Contig_View]  NDFIP1 [Vega]
ICGC DataPortalENSG00000131507
TCGA cBioPortalNDFIP1
AceView (NCBI)NDFIP1
Genatlas (Paris)NDFIP1
WikiGenes80762
SOURCE (Princeton)NDFIP1
Genetics Home Reference (NIH)NDFIP1
Genomic and cartography
GoldenPath hg19 (UCSC)NDFIP1  -     chr5:141488324-141534008 +  5q31.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NDFIP1  -     5q31.3   [Description]    (hg38-Dec_2013)
EnsemblNDFIP1 - 5q31.3 [CytoView hg19]  NDFIP1 - 5q31.3 [CytoView hg38]
Mapping of homologs : NCBINDFIP1 [Mapview hg19]  NDFIP1 [Mapview hg38]
OMIM612050   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_030571
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NDFIP1
Cluster EST : UnigeneHs.653510 [ NCBI ]
CGAP (NCI)Hs.653510
Alternative Splicing GalleryENSG00000131507
Gene ExpressionNDFIP1 [ NCBI-GEO ]   NDFIP1 [ EBI - ARRAY_EXPRESS ]   NDFIP1 [ SEEK ]   NDFIP1 [ MEM ]
Gene Expression Viewer (FireBrowse)NDFIP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80762
GTEX Portal (Tissue expression)NDFIP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BT67   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BT67  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BT67
Splice isoforms : SwissVarQ9BT67
PhosPhoSitePlusQ9BT67
Domains : Interpro (EBI)NEDD4/Bsd2   
Domain families : Pfam (Sanger)DUF2370 (PF10176)   
Domain families : Pfam (NCBI)pfam10176   
Conserved Domain (NCBI)NDFIP1
DMDM Disease mutations80762
Blocks (Seattle)NDFIP1
SuperfamilyQ9BT67
Human Protein AtlasENSG00000131507
Peptide AtlasQ9BT67
HPRD14816
IPIIPI00012235   IPI00179987   
Protein Interaction databases
DIP (DOE-UCLA)Q9BT67
IntAct (EBI)Q9BT67
FunCoupENSG00000131507
BioGRIDNDFIP1
STRING (EMBL)NDFIP1
ZODIACNDFIP1
Ontologies - Pathways
QuickGOQ9BT67
Ontology : AmiGOGolgi membrane  regulation of myeloid leukocyte differentiation  negative regulation of type 2 immune response  signal transducer activity  protein binding  extracellular region  cell cortex  cellular iron ion homeostasis  vacuolar transport  signal transduction  endosome membrane  negative regulation of gene expression  integral component of membrane  metal ion transport  positive regulation of protein ubiquitination  positive regulation of protein ubiquitination  negative regulation of transporter activity  negative regulation of interleukin-4 production  negative regulation of T cell proliferation  positive regulation of I-kappaB kinase/NF-kappaB signaling  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  regulation of lymphocyte differentiation  positive regulation of protein catabolic process  negative regulation of isotype switching to IgE isotypes  regulation of isotype switching to IgG isotypes  perinuclear region of cytoplasm  negative regulation of inflammatory response  negative regulation of protein transport  
Ontology : EGO-EBIGolgi membrane  regulation of myeloid leukocyte differentiation  negative regulation of type 2 immune response  signal transducer activity  protein binding  extracellular region  cell cortex  cellular iron ion homeostasis  vacuolar transport  signal transduction  endosome membrane  negative regulation of gene expression  integral component of membrane  metal ion transport  positive regulation of protein ubiquitination  positive regulation of protein ubiquitination  negative regulation of transporter activity  negative regulation of interleukin-4 production  negative regulation of T cell proliferation  positive regulation of I-kappaB kinase/NF-kappaB signaling  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway  regulation of lymphocyte differentiation  positive regulation of protein catabolic process  negative regulation of isotype switching to IgE isotypes  regulation of isotype switching to IgG isotypes  perinuclear region of cytoplasm  negative regulation of inflammatory response  negative regulation of protein transport  
NDEx NetworkNDFIP1
Atlas of Cancer Signalling NetworkNDFIP1
Wikipedia pathwaysNDFIP1
Orthology - Evolution
OrthoDB80762
GeneTree (enSembl)ENSG00000131507
Phylogenetic Trees/Animal Genes : TreeFamNDFIP1
HOVERGENQ9BT67
HOGENOMQ9BT67
Homologs : HomoloGeneNDFIP1
Homology/Alignments : Family Browser (UCSC)NDFIP1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNDFIP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NDFIP1
dbVarNDFIP1
ClinVarNDFIP1
1000_GenomesNDFIP1 
Exome Variant ServerNDFIP1
ExAC (Exome Aggregation Consortium)NDFIP1 (select the gene name)
Genetic variants : HAPMAP80762
Genomic Variants (DGV)NDFIP1 [DGVbeta]
DECIPHER (Syndromes)5:141488324-141534008  ENSG00000131507
CONAN: Copy Number AnalysisNDFIP1 
Mutations
ICGC Data PortalNDFIP1 
TCGA Data PortalNDFIP1 
Broad Tumor PortalNDFIP1
OASIS PortalNDFIP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNDFIP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNDFIP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NDFIP1
DgiDB (Drug Gene Interaction Database)NDFIP1
DoCM (Curated mutations)NDFIP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NDFIP1 (select a term)
intoGenNDFIP1
Cancer3DNDFIP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612050   
Orphanet
MedgenNDFIP1
Genetic Testing Registry NDFIP1
NextProtQ9BT67 [Medical]
TSGene80762
GENETestsNDFIP1
Huge Navigator NDFIP1 [HugePedia]
snp3D : Map Gene to Disease80762
BioCentury BCIQNDFIP1
ClinGenNDFIP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80762
Chemical/Pharm GKB GenePA134943402
Clinical trialNDFIP1
Miscellaneous
canSAR (ICR)NDFIP1 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNDFIP1
EVEXNDFIP1
GoPubMedNDFIP1
iHOPNDFIP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Mar 30 15:11:55 CEST 2017

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