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NDN (necdin, MAGE family member)

Identity

Alias_namesnecdin homolog (mouse)
necdin, melanoma antigen (MAGE) family member
Alias_symbol (synonym)HsT16328
PWCR
Other alias
HGNC (Hugo) NDN
LocusID (NCBI) 4692
Atlas_Id 51233
Location 15q11.2  [Link to chromosome band 15q11]
Location_base_pair Starts at 23930554 and ends at 23932450 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Cancer prone implicated (Data extracted from papers in the Atlas) [ 1 ]
  Prader Willi syndrome


External links

Nomenclature
HGNC (Hugo)NDN   7675
LRG (Locus Reference Genomic)LRG_1047
Cards
Entrez_Gene (NCBI)NDN  4692  necdin, MAGE family member
AliasesHsT16328; PWCR
GeneCards (Weizmann)NDN
Ensembl hg19 (Hinxton)ENSG00000182636 [Gene_View]  chr15:23930554-23932450 [Contig_View]  NDN [Vega]
Ensembl hg38 (Hinxton)ENSG00000182636 [Gene_View]  chr15:23930554-23932450 [Contig_View]  NDN [Vega]
ICGC DataPortalENSG00000182636
TCGA cBioPortalNDN
AceView (NCBI)NDN
Genatlas (Paris)NDN
WikiGenes4692
SOURCE (Princeton)NDN
Genetics Home Reference (NIH)NDN
Genomic and cartography
GoldenPath hg19 (UCSC)NDN  -     chr15:23930554-23932450 -  15q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NDN  -     15q11.2   [Description]    (hg38-Dec_2013)
EnsemblNDN - 15q11.2 [CytoView hg19]  NDN - 15q11.2 [CytoView hg38]
Mapping of homologs : NCBINDN [Mapview hg19]  NDN [Mapview hg38]
OMIM176270   602117   
Gene and transcription
Genbank (Entrez)AK129654 AK312779 BC008750 HQ448156 KJ534888
RefSeq transcript (Entrez)NM_002487
RefSeq genomic (Entrez)NC_000015 NC_018926 NG_009380 NT_010194 NW_004929397
Consensus coding sequences : CCDS (NCBI)NDN
Cluster EST : UnigeneHs.50130 [ NCBI ]
CGAP (NCI)Hs.50130
Alternative Splicing GalleryENSG00000182636
Gene ExpressionNDN [ NCBI-GEO ]   NDN [ EBI - ARRAY_EXPRESS ]   NDN [ SEEK ]   NDN [ MEM ]
Gene Expression Viewer (FireBrowse)NDN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4692
GTEX Portal (Tissue expression)NDN
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99608   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99608  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99608
Splice isoforms : SwissVarQ99608
PhosPhoSitePlusQ99608
Domaine pattern : Prosite (Expaxy)MAGE (PS50838)   
Domains : Interpro (EBI)MHD_dom    Necdin   
Domain families : Pfam (Sanger)MAGE (PF01454)   
Domain families : Pfam (NCBI)pfam01454   
Conserved Domain (NCBI)NDN
DMDM Disease mutations4692
Blocks (Seattle)NDN
SuperfamilyQ99608
Human Protein AtlasENSG00000182636
Peptide AtlasQ99608
HPRD03667
IPIIPI00001102   
Protein Interaction databases
DIP (DOE-UCLA)Q99608
IntAct (EBI)Q99608
FunCoupENSG00000182636
BioGRIDNDN
STRING (EMBL)NDN
ZODIACNDN
Ontologies - Pathways
QuickGOQ99608
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  neuron migration  respiratory system process  nucleus  centrosome  cytosol  transcription from RNA polymerase II promoter  nervous system development  axonal fasciculation  central nervous system development  negative regulation of cell proliferation  glial cell migration  post-embryonic development  sensory perception of pain  regulation of growth  cell projection  gamma-tubulin binding  perikaryon  positive regulation of transcription from RNA polymerase II promoter  neurotrophin TRK receptor signaling pathway  axon extension  multicellular organismal homeostasis  genetic imprinting  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  neuron migration  respiratory system process  nucleus  centrosome  cytosol  transcription from RNA polymerase II promoter  nervous system development  axonal fasciculation  central nervous system development  negative regulation of cell proliferation  glial cell migration  post-embryonic development  sensory perception of pain  regulation of growth  cell projection  gamma-tubulin binding  perikaryon  positive regulation of transcription from RNA polymerase II promoter  neurotrophin TRK receptor signaling pathway  axon extension  multicellular organismal homeostasis  genetic imprinting  
NDEx NetworkNDN
Atlas of Cancer Signalling NetworkNDN
Wikipedia pathwaysNDN
Orthology - Evolution
OrthoDB4692
GeneTree (enSembl)ENSG00000182636
Phylogenetic Trees/Animal Genes : TreeFamNDN
HOVERGENQ99608
HOGENOMQ99608
Homologs : HomoloGeneNDN
Homology/Alignments : Family Browser (UCSC)NDN
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNDN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NDN
dbVarNDN
ClinVarNDN
1000_GenomesNDN 
Exome Variant ServerNDN
ExAC (Exome Aggregation Consortium)NDN (select the gene name)
Genetic variants : HAPMAP4692
Genomic Variants (DGV)NDN [DGVbeta]
DECIPHER (Syndromes)15:23930554-23932450  ENSG00000182636
CONAN: Copy Number AnalysisNDN 
Mutations
ICGC Data PortalNDN 
TCGA Data PortalNDN 
Broad Tumor PortalNDN
OASIS PortalNDN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNDN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNDN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NDN
DgiDB (Drug Gene Interaction Database)NDN
DoCM (Curated mutations)NDN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NDN (select a term)
intoGenNDN
Cancer3DNDN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176270    602117   
Orphanet17992    17993    17995    13771   
MedgenNDN
Genetic Testing Registry NDN
NextProtQ99608 [Medical]
TSGene4692
GENETestsNDN
Huge Navigator NDN [HugePedia]
snp3D : Map Gene to Disease4692
BioCentury BCIQNDN
ClinGenNDN (curated)
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4692
Chemical/Pharm GKB GenePA31479
Clinical trialNDN
Miscellaneous
canSAR (ICR)NDN (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNDN
EVEXNDN
GoPubMedNDN
iHOPNDN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:18:26 CET 2017

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