Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

NDN (necdin, MAGE family member)

Identity

Alias (NCBI)HsT16328
PWCR
HGNC (Hugo) NDN
HGNC Alias symbHsT16328
PWCR
HGNC Alias namePrader-Willi syndrome chromosome region
HGNC Previous namenecdin homolog (mouse)
 necdin, melanoma antigen (MAGE) family member
LocusID (NCBI) 4692
Atlas_Id 51233
Location 15q11.2  [Link to chromosome band 15q11]
Location_base_pair Starts at 23685400 and ends at 23687305 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Cancer prone implicated (Data extracted from papers in the Atlas) [ 1 ]
  Prader Willi syndrome


External links

Nomenclature
HGNC (Hugo)NDN   7675
LRG (Locus Reference Genomic)LRG_1047
Cards
Entrez_Gene (NCBI)NDN    necdin, MAGE family member
AliasesHsT16328; PWCR
GeneCards (Weizmann)NDN
Ensembl hg19 (Hinxton)ENSG00000182636 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000182636 [Gene_View]  ENSG00000182636 [Sequence]  chr15:23685400-23687305 [Contig_View]  NDN [Vega]
ICGC DataPortalENSG00000182636
TCGA cBioPortalNDN
AceView (NCBI)NDN
Genatlas (Paris)NDN
SOURCE (Princeton)NDN
Genetics Home Reference (NIH)NDN
Genomic and cartography
GoldenPath hg38 (UCSC)NDN  -     chr15:23685400-23687305 -  15q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NDN  -     15q11.2   [Description]    (hg19-Feb_2009)
GoldenPathNDN - 15q11.2 [CytoView hg19]  NDN - 15q11.2 [CytoView hg38]
ImmunoBaseENSG00000182636
genome Data Viewer NCBINDN [Mapview hg19]  
OMIM176270   602117   
Gene and transcription
Genbank (Entrez)AK129654 AK312779 BC008750 KJ534888 KJ535010
RefSeq transcript (Entrez)NM_002487
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NDN
Alternative Splicing GalleryENSG00000182636
Gene ExpressionNDN [ NCBI-GEO ]   NDN [ EBI - ARRAY_EXPRESS ]   NDN [ SEEK ]   NDN [ MEM ]
Gene Expression Viewer (FireBrowse)NDN [ Firebrowse - Broad ]
GenevisibleExpression of NDN in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4692
GTEX Portal (Tissue expression)NDN
Human Protein AtlasENSG00000182636-NDN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99608   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99608  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99608
Splice isoforms : SwissVarQ99608
PhosPhoSitePlusQ99608
Domaine pattern : Prosite (Expaxy)MAGE (PS50838)   
Domains : Interpro (EBI)MAGE    MAGE_WH1    MAGE_WH2    MHD_dom    Necdin   
Domain families : Pfam (Sanger)MAGE (PF01454)   
Domain families : Pfam (NCBI)pfam01454   
Domain families : Smart (EMBL)MAGE (SM01373)  
Conserved Domain (NCBI)NDN
Blocks (Seattle)NDN
SuperfamilyQ99608
Human Protein Atlas [tissue]ENSG00000182636-NDN [tissue]
Peptide AtlasQ99608
HPRD03667
IPIIPI00001102   
Protein Interaction databases
DIP (DOE-UCLA)Q99608
IntAct (EBI)Q99608
BioGRIDNDN
STRING (EMBL)NDN
ZODIACNDN
Ontologies - Pathways
QuickGOQ99608
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription activator activity, RNA polymerase II-specific  neuron migration  respiratory system process  protein binding  nucleoplasm  nucleoplasm  centrosome  cytosol  axonal fasciculation  central nervous system development  negative regulation of cell population proliferation  glial cell migration  post-embryonic development  cytokine-mediated signaling pathway  sensory perception of pain  protein-containing complex  regulation of growth  cell projection  gamma-tubulin binding  perikaryon  negative regulation of DNA-binding transcription factor activity  positive regulation of transcription by RNA polymerase II  neurotrophin TRK receptor signaling pathway  axon extension  multicellular organismal homeostasis  genetic imprinting  positive regulation of protein deacetylation  promoter-specific chromatin binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription activator activity, RNA polymerase II-specific  neuron migration  respiratory system process  protein binding  nucleoplasm  nucleoplasm  centrosome  cytosol  axonal fasciculation  central nervous system development  negative regulation of cell population proliferation  glial cell migration  post-embryonic development  cytokine-mediated signaling pathway  sensory perception of pain  protein-containing complex  regulation of growth  cell projection  gamma-tubulin binding  perikaryon  negative regulation of DNA-binding transcription factor activity  positive regulation of transcription by RNA polymerase II  neurotrophin TRK receptor signaling pathway  axon extension  multicellular organismal homeostasis  genetic imprinting  positive regulation of protein deacetylation  promoter-specific chromatin binding  
NDEx NetworkNDN
Atlas of Cancer Signalling NetworkNDN
Wikipedia pathwaysNDN
Orthology - Evolution
OrthoDB4692
GeneTree (enSembl)ENSG00000182636
Phylogenetic Trees/Animal Genes : TreeFamNDN
HOGENOMQ99608
Homologs : HomoloGeneNDN
Homology/Alignments : Family Browser (UCSC)NDN
Gene fusions - Rearrangements
Fusion : QuiverNDN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNDN [hg38]
dbVarNDN
ClinVarNDN
MonarchNDN
1000_GenomesNDN 
Exome Variant ServerNDN
GNOMAD BrowserENSG00000182636
Varsome BrowserNDN
Genomic Variants (DGV)NDN [DGVbeta]
DECIPHERNDN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNDN 
Mutations
ICGC Data PortalNDN 
TCGA Data PortalNDN 
Broad Tumor PortalNDN
OASIS PortalNDN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNDN  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNDN
Mutations and Diseases : HGMDNDN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NDN
DgiDB (Drug Gene Interaction Database)NDN
DoCM (Curated mutations)NDN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NDN (select a term)
intoGenNDN
Cancer3DNDN(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176270    602117   
Orphanet17992    17993    17995    13771   
DisGeNETNDN
MedgenNDN
Genetic Testing Registry NDN
NextProtQ99608 [Medical]
GENETestsNDN
Target ValidationNDN
Huge Navigator NDN [HugePedia]
ClinGenNDN (curated)
Clinical trials, drugs, therapy
MyCancerGenomeNDN
Protein Interactions : CTD
Pharm GKB GenePA31479
PharosQ99608
Clinical trialNDN
Miscellaneous
canSAR (ICR)NDN (select the gene name)
HarmonizomeNDN
DataMed IndexNDN
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXNDN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:36:04 CET 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.