NDRG3 (NDRG family member 3)

2009-01-01  

Identity

HGNC
LOCATION
20q11.23
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 57446
MIM: 605273
HGNC: 14462
Ensembl: ENSG00000101079

Variants:

dbSNP: 57446
ClinVar: 57446
TCGA: ENSG00000101079
COSMIC: NDRG3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101079ENST00000349004Q9UGV2
ENSG00000101079ENST00000359675Q9UGV2
ENSG00000101079ENST00000373773F8WBF9
ENSG00000101079ENST00000373803Q5TH30
ENSG00000101079ENST00000422536Q5TH29

Expression (GTEx)

0
50
100
150
200
250
300
350

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371727272023Lactate promotes neuronal differentiation of SH-SY5Y cells by lactate-responsive gene sets through NDRG3-dependent and -independent manners.4
373504102023NDRG3 regulates imatinib resistance by promoting β‑catenin accumulation in the nucleus in chronic myelogenous leukemia.0
371727272023Lactate promotes neuronal differentiation of SH-SY5Y cells by lactate-responsive gene sets through NDRG3-dependent and -independent manners.4
373504102023NDRG3 regulates imatinib resistance by promoting β‑catenin accumulation in the nucleus in chronic myelogenous leukemia.0
335629892021High expression of NDRG3 correlates with poor prognosis in gastric cancer patients.1
335831232021The LINC01410/miR-122-5p/NDRG3 axis is involved in the proliferation and migration of osteosarcoma cells.7
335629892021High expression of NDRG3 correlates with poor prognosis in gastric cancer patients.1
335831232021The LINC01410/miR-122-5p/NDRG3 axis is involved in the proliferation and migration of osteosarcoma cells.7
319358612020Structural and Biophysical Analyses of Human N-Myc Downstream-Regulated Gene 3 (NDRG3) Protein.4
319358612020Structural and Biophysical Analyses of Human N-Myc Downstream-Regulated Gene 3 (NDRG3) Protein.4
310724452019High NDRG3 expression facilitates HCC metastasis by promoting nuclear translocation of β-catenin.6
310724452019High NDRG3 expression facilitates HCC metastasis by promoting nuclear translocation of β-catenin.6
291719882018High expression of NDRG3 associates with unfavorable overall survival in non-small cell lung cancer.11
297604172018NDRG3 lowers the metastatic potential in prostate cancer as a feedback controller of hypoxia-inducible factors.9
304136092018NDRG3 overexpression is associated with a poor prognosis in patients with hepatocellular carcinoma.8

Citation

Dessen P

NDRG3 (NDRG family member 3)

Atlas Genet Cytogenet Oncol Haematol. 2009-01-01

Online version: http://atlasgeneticsoncology.org/gene/50661/ndrg3