NDRG3 (NDRG family member 3)

2009-01-01  

Identity

HGNC
LOCATION
20q11.23
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 57446
MIM: 605273
HGNC: 14462
Ensembl: ENSG00000101079

Variants:

dbSNP: 57446
ClinVar: 57446
TCGA: ENSG00000101079
COSMIC: NDRG3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101079ENST00000349004Q9UGV2
ENSG00000101079ENST00000359675Q9UGV2
ENSG00000101079ENST00000373773F8WBF9
ENSG00000101079ENST00000373803Q5TH30
ENSG00000101079ENST00000422536Q5TH29

Expression (GTEx)

0
50
100
150
200
250
300
350

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
119368452002Characterization and expression of three novel differentiation-related genes belong to the human NDRG gene family.72
217256182011miR-122 inhibits viral replication and cell proliferation in hepatitis B virus-related hepatocellular carcinoma and targets NDRG3.36
189753802009NDRG3 is an androgen regulated and prostate enriched gene that promotes in vitro and in vivo prostate cancer cell growth.24
282697582017MicroRNA31-NDRG3 regulation axes are essential for hepatocellular carcinoma survival and drug resistance.14
242221852014Prognostic impact of NDRG2 and NDRG3 in prostate cancer patients undergoing radical prostatectomy.12
237257562013NDRG3 and NDRG4, two novel tumor-related genes.10
259367802015NDRG3-mediated lactate signaling in hypoxia.7
277805952016High expression of NDRG3 associates with positive lymph node metastasis and unfavourable overall survival in laryngeal squamous cell carcinoma.6
291719882018High expression of NDRG3 associates with unfavorable overall survival in non-small cell lung cancer.6
283268362017Clinical significance of NDRG3 in patients with breast cancer.5

Citation

Dessen P

NDRG3 (NDRG family member 3)

Atlas Genet Cytogenet Oncol Haematol. 2009-01-01

Online version: http://atlasgeneticsoncology.org/gene/50661/ndrg3