NDST3 (N-deacetylase and N-sulfotransferase 3)

2003-05-01  

Identity

HGNC
LOCATION
4q26
LOCUSID
ALIAS
HSST3
FUSION GENES

Other Information

Locus ID:

NCBI: 9348
MIM: 603950
HGNC: 7682
Ensembl: ENSG00000164100

Variants:

dbSNP: 9348
ClinVar: 9348
TCGA: ENSG00000164100
COSMIC: NDST3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164100ENST00000296499O95803

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Glycosaminoglycan biosynthesis - heparan sulfate / heparinKEGGko00534
Glycosaminoglycan biosynthesis - heparan sulfate / heparinKEGGhsa00534
Metabolic pathwaysKEGGhsa01100
Glycosaminoglycan biosynthesis, heparan sulfate backboneKEGGhsa_M00059
Glycosaminoglycan biosynthesis, heparan sulfate backboneKEGGM00059
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Heparan sulfate/heparin (HS-GAG) metabolismREACTOMER-HSA-1638091
HS-GAG biosynthesisREACTOMER-HSA-2022928

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
242533402013Genome-wide association study implicates NDST3 in schizophrenia and bipolar disorder.36
205495152010Genome-wide searching of rare genetic variants in WTCCC data.29
203320992010A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.8
267314382016A comprehensive analysis of NDST3 for schizophrenia and bipolar disorder in Han Chinese.6
251395292014rs11098403 polymorphism near NDST3 is associated with a reduced risk of schizophrenia in a Han Chinese population.1
291405832018Association study of NDST3 gene for schizophrenia, bipolar disorder, major depressive disorder in the Han Chinese population.1

Citation

Dessen P

NDST3 (N-deacetylase and N-sulfotransferase 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41514/ndst3