NDUFA10 (NADH:ubiquinone oxidoreductase subunit A10)

2013-03-01  

Identity

HGNC
LOCATION
2q37.3
LOCUSID
ALIAS
CI-42KD,CI-42k,MC1DN22
FUSION GENES

Other Information

Locus ID:

NCBI: 4705
MIM: 603835
HGNC: 7684
Ensembl: ENSG00000130414

Variants:

dbSNP: 4705
ClinVar: 4705
TCGA: ENSG00000130414
COSMIC: NDUFA10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130414ENST00000252711O95299
ENSG00000130414ENST00000252711A0A024R4B3
ENSG00000130414ENST00000307300O95299
ENSG00000130414ENST00000404554E7ESZ7
ENSG00000130414ENST00000407129Q8N1B9
ENSG00000130414ENST00000414580F8WEH0
ENSG00000130414ENST00000419408H7C2W5
ENSG00000130414ENST00000443626C9J6X0
ENSG00000130414ENST00000444548H7C1Y7
ENSG00000130414ENST00000448880H7C2X4
ENSG00000130414ENST00000620965A0A087WXC5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Pathways

PathwaySourceExternal ID
Oxidative phosphorylationKEGGko00190
Alzheimer's diseaseKEGGko05010
Huntington's diseaseKEGGko05016
Oxidative phosphorylationKEGGhsa00190
Alzheimer's diseaseKEGGhsa05010
Parkinson's diseaseKEGGhsa05012
Huntington's diseaseKEGGhsa05016
Metabolic pathwaysKEGGhsa01100
NADH dehydrogenase (ubiquinone) 1 alpha subcomplexKEGGhsa_M00146
Non-alcoholic fatty liver disease (NAFLD)KEGGhsa04932
Non-alcoholic fatty liver disease (NAFLD)KEGGko04932
NADH dehydrogenase (ubiquinone) 1 alpha subcomplexKEGGM00146
MetabolismREACTOMER-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transportREACTOMER-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.REACTOMER-HSA-163200
Respiratory electron transportREACTOMER-HSA-611105
Complex I biogenesisREACTOMER-HSA-6799198

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
176013502007A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.27
224619102012FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma.27
189772412008Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey.20
190645712008Polymorphisms in mitochondrial genes and prostate cancer risk.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
193430462009Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.3

Citation

Dessen P

NDUFA10 (NADH:ubiquinone oxidoreductase subunit A10)

Atlas Genet Cytogenet Oncol Haematol. 2013-03-01

Online version: http://atlasgeneticsoncology.org/gene/53210/ndufa10