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NDUFA10 (NADH:ubiquinone oxidoreductase subunit A10)

Identity

Alias_namesNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10 (42kD)
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
Alias_symbol (synonym)CI-42k
Other aliasCI-42KD
HGNC (Hugo) NDUFA10
LocusID (NCBI) 4705
Atlas_Id 53210
Location Xq24  [Link to chromosome band Xq24]
Location_base_pair Starts at 239957372 and ends at 240025402 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NDUFA10 (2q37.3) / HLA-DQA1 (6p21.32)NDUFA10 (2q37.3) / NDUFA10 (2q37.3)NDUFA10 (2q37.3) / SGPP2 (2q36.1)
NDUFA10 (2q37.3) / SLAIN2 (4p11)NDUFA10 2q37.3 / SGPP2 2q36.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(2;2)(q36;q37) NDUFA10/SGPP2


External links

Nomenclature
HGNC (Hugo)NDUFA10   7684
Cards
Entrez_Gene (NCBI)NDUFA10  4705  NADH:ubiquinone oxidoreductase subunit A10
AliasesCI-42KD; CI-42k
GeneCards (Weizmann)NDUFA10
Ensembl hg19 (Hinxton)ENSG00000130414 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130414 [Gene_View]  ENSG00000130414 [Sequence]  chr2:239957372-240025402 [Contig_View]  NDUFA10 [Vega]
ICGC DataPortalENSG00000130414
TCGA cBioPortalNDUFA10
AceView (NCBI)NDUFA10
Genatlas (Paris)NDUFA10
WikiGenes4705
SOURCE (Princeton)NDUFA10
Genetics Home Reference (NIH)NDUFA10
Genomic and cartography
GoldenPath hg38 (UCSC)NDUFA10  -     chr2:239957372-240025402 -  Xq24   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NDUFA10  -     Xq24   [Description]    (hg19-Feb_2009)
EnsemblNDUFA10 - Xq24 [CytoView hg19]  NDUFA10 - Xq24 [CytoView hg38]
Mapping of homologs : NCBINDUFA10 [Mapview hg19]  NDUFA10 [Mapview hg38]
OMIM256000   603835   
Gene and transcription
Genbank (Entrez)AB209440 AF087661 AF087854 AF453834 AK025576
RefSeq transcript (Entrez)NM_001322019 NM_001322020 NM_004544
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NDUFA10
Cluster EST : UnigeneHs.277677 [ NCBI ]
CGAP (NCI)Hs.277677
Alternative Splicing GalleryENSG00000130414
Gene ExpressionNDUFA10 [ NCBI-GEO ]   NDUFA10 [ EBI - ARRAY_EXPRESS ]   NDUFA10 [ SEEK ]   NDUFA10 [ MEM ]
Gene Expression Viewer (FireBrowse)NDUFA10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4705
GTEX Portal (Tissue expression)NDUFA10
Human Protein AtlasENSG00000130414-NDUFA10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95299   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95299  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95299
Splice isoforms : SwissVarO95299
PhosPhoSitePlusO95299
Domains : Interpro (EBI)DNK_dom    NDUFA10    P-loop_NTPase   
Domain families : Pfam (Sanger)dNK (PF01712)   
Domain families : Pfam (NCBI)pfam01712   
Conserved Domain (NCBI)NDUFA10
DMDM Disease mutations4705
Blocks (Seattle)NDUFA10
PDB (SRS)5XTC    5XTD    5XTH    5XTI   
PDB (PDBSum)5XTC    5XTD    5XTH    5XTI   
PDB (IMB)5XTC    5XTD    5XTH    5XTI   
PDB (RSDB)5XTC    5XTD    5XTH    5XTI   
Structural Biology KnowledgeBase5XTC    5XTD    5XTH    5XTI   
SCOP (Structural Classification of Proteins)5XTC    5XTD    5XTH    5XTI   
CATH (Classification of proteins structures)5XTC    5XTD    5XTH    5XTI   
SuperfamilyO95299
Human Protein Atlas [tissue]ENSG00000130414-NDUFA10 [tissue]
Peptide AtlasO95299
HPRD11950
IPIIPI00029561   IPI01009940   IPI00555877   IPI00894559   IPI00103509   IPI00894154   IPI00894261   IPI00893863   IPI00893990   IPI00893727   IPI00893311   
Protein Interaction databases
DIP (DOE-UCLA)O95299
IntAct (EBI)O95299
FunCoupENSG00000130414
BioGRIDNDUFA10
STRING (EMBL)NDUFA10
ZODIACNDUFA10
Ontologies - Pathways
QuickGOO95299
Ontology : AmiGOcytoplasm  mitochondrion  mitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial matrix  mitochondrial electron transport, NADH to ubiquinone  mitochondrial electron transport, NADH to ubiquinone  NADH dehydrogenase (ubiquinone) activity  deoxynucleoside kinase activity  mitochondrial respiratory chain complex I assembly  mitochondrial respiratory chain complex I assembly  myelin sheath  
Ontology : EGO-EBIcytoplasm  mitochondrion  mitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial matrix  mitochondrial electron transport, NADH to ubiquinone  mitochondrial electron transport, NADH to ubiquinone  NADH dehydrogenase (ubiquinone) activity  deoxynucleoside kinase activity  mitochondrial respiratory chain complex I assembly  mitochondrial respiratory chain complex I assembly  myelin sheath  
Pathways : KEGGOxidative phosphorylation    Non-alcoholic fatty liver disease (NAFLD)    Alzheimer's disease    Parkinson's disease    Huntington's disease   
NDEx NetworkNDUFA10
Atlas of Cancer Signalling NetworkNDUFA10
Wikipedia pathwaysNDUFA10
Orthology - Evolution
OrthoDB4705
GeneTree (enSembl)ENSG00000130414
Phylogenetic Trees/Animal Genes : TreeFamNDUFA10
HOVERGENO95299
HOGENOMO95299
Homologs : HomoloGeneNDUFA10
Homology/Alignments : Family Browser (UCSC)NDUFA10
Gene fusions - Rearrangements
Fusion : MitelmanNDUFA10/SGPP2 [2q37.3/2q36.1]  
Fusion PortalNDUFA10 2q37.3 SGPP2 2q36.1 LUSC
Fusion : QuiverNDUFA10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNDUFA10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NDUFA10
dbVarNDUFA10
ClinVarNDUFA10
1000_GenomesNDUFA10 
Exome Variant ServerNDUFA10
ExAC (Exome Aggregation Consortium)ENSG00000130414
GNOMAD BrowserENSG00000130414
Varsome BrowserNDUFA10
Genetic variants : HAPMAP4705
Genomic Variants (DGV)NDUFA10 [DGVbeta]
DECIPHERNDUFA10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNDUFA10 
Mutations
ICGC Data PortalNDUFA10 
TCGA Data PortalNDUFA10 
Broad Tumor PortalNDUFA10
OASIS PortalNDUFA10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNDUFA10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNDUFA10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NDUFA10
DgiDB (Drug Gene Interaction Database)NDUFA10
DoCM (Curated mutations)NDUFA10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NDUFA10 (select a term)
intoGenNDUFA10
Cancer3DNDUFA10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM256000    603835   
Orphanet19814   
DisGeNETNDUFA10
MedgenNDUFA10
Genetic Testing Registry NDUFA10
NextProtO95299 [Medical]
TSGene4705
GENETestsNDUFA10
Target ValidationNDUFA10
Huge Navigator NDUFA10 [HugePedia]
snp3D : Map Gene to Disease4705
BioCentury BCIQNDUFA10
ClinGenNDUFA10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4705
Chemical/Pharm GKB GenePA31490
Clinical trialNDUFA10
Miscellaneous
canSAR (ICR)NDUFA10 (select the gene name)
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNDUFA10
EVEXNDUFA10
GoPubMedNDUFA10
iHOPNDUFA10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Aug 16 11:19:17 CEST 2018

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