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NDUFB1 (NADH:ubiquinone oxidoreductase subunit B1)

Identity

Alias_namesNADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1 (7kD, MNLL)
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
Alias_symbol (synonym)MNLL
CI-MNLL
Other aliasCI-SGDH
HGNC (Hugo) NDUFB1
LocusID (NCBI) 4707
Atlas_Id 70769
Location 14q32.12  [Link to chromosome band 14q32]
Location_base_pair Starts at 92116124 and ends at 92121809 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NDUFB1 (14q32.12) / FKBP8 (19p13.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NDUFB1   7695
Cards
Entrez_Gene (NCBI)NDUFB1  4707  NADH:ubiquinone oxidoreductase subunit B1
AliasesCI-MNLL; CI-SGDH; MNLL
GeneCards (Weizmann)NDUFB1
Ensembl hg19 (Hinxton)ENSG00000183648 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183648 [Gene_View]  chr14:92116124-92121809 [Contig_View]  NDUFB1 [Vega]
ICGC DataPortalENSG00000183648
TCGA cBioPortalNDUFB1
AceView (NCBI)NDUFB1
Genatlas (Paris)NDUFB1
WikiGenes4707
SOURCE (Princeton)NDUFB1
Genetics Home Reference (NIH)NDUFB1
Genomic and cartography
GoldenPath hg38 (UCSC)NDUFB1  -     chr14:92116124-92121809 -  14q32.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NDUFB1  -     14q32.12   [Description]    (hg19-Feb_2009)
EnsemblNDUFB1 - 14q32.12 [CytoView hg19]  NDUFB1 - 14q32.12 [CytoView hg38]
Mapping of homologs : NCBINDUFB1 [Mapview hg19]  NDUFB1 [Mapview hg38]
OMIM603837   
Gene and transcription
Genbank (Entrez)AF050638 AK055348 AK316557 BC009691 BC104672
RefSeq transcript (Entrez)NM_004545
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NDUFB1
Cluster EST : UnigeneHs.183435 [ NCBI ]
CGAP (NCI)Hs.183435
Alternative Splicing GalleryENSG00000183648
Gene ExpressionNDUFB1 [ NCBI-GEO ]   NDUFB1 [ EBI - ARRAY_EXPRESS ]   NDUFB1 [ SEEK ]   NDUFB1 [ MEM ]
Gene Expression Viewer (FireBrowse)NDUFB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4707
GTEX Portal (Tissue expression)NDUFB1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75438   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75438  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75438
Splice isoforms : SwissVarO75438
PhosPhoSitePlusO75438
Domains : Interpro (EBI)NADH_UbQ_OxRdtase_MNLL_su   
Domain families : Pfam (Sanger)NADH_oxidored (PF08040)   
Domain families : Pfam (NCBI)pfam08040   
Domain structure : Prodom (Prabi Lyon)NADH_UbQ_OxRdtase_MNLL_su (PD052001)   
Conserved Domain (NCBI)NDUFB1
DMDM Disease mutations4707
Blocks (Seattle)NDUFB1
SuperfamilyO75438
Human Protein AtlasENSG00000183648
Peptide AtlasO75438
HPRD11952
IPIIPI00943798   IPI00025725   IPI01025477   
Protein Interaction databases
DIP (DOE-UCLA)O75438
IntAct (EBI)O75438
FunCoupENSG00000183648
BioGRIDNDUFB1
STRING (EMBL)NDUFB1
ZODIACNDUFB1
Ontologies - Pathways
QuickGOO75438
Ontology : AmiGOmitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial electron transport, NADH to ubiquinone  mitochondrial electron transport, NADH to ubiquinone  NADH dehydrogenase (ubiquinone) activity  integral component of membrane  nuclear speck  mitochondrial respiratory chain complex I assembly  extracellular exosome  
Ontology : EGO-EBImitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial electron transport, NADH to ubiquinone  mitochondrial electron transport, NADH to ubiquinone  NADH dehydrogenase (ubiquinone) activity  integral component of membrane  nuclear speck  mitochondrial respiratory chain complex I assembly  extracellular exosome  
Pathways : KEGGOxidative phosphorylation    Non-alcoholic fatty liver disease (NAFLD)    Alzheimer's disease    Parkinson's disease    Huntington's disease   
NDEx NetworkNDUFB1
Atlas of Cancer Signalling NetworkNDUFB1
Wikipedia pathwaysNDUFB1
Orthology - Evolution
OrthoDB4707
GeneTree (enSembl)ENSG00000183648
Phylogenetic Trees/Animal Genes : TreeFamNDUFB1
HOVERGENO75438
HOGENOMO75438
Homologs : HomoloGeneNDUFB1
Homology/Alignments : Family Browser (UCSC)NDUFB1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNDUFB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NDUFB1
dbVarNDUFB1
ClinVarNDUFB1
1000_GenomesNDUFB1 
Exome Variant ServerNDUFB1
ExAC (Exome Aggregation Consortium)NDUFB1 (select the gene name)
Genetic variants : HAPMAP4707
Genomic Variants (DGV)NDUFB1 [DGVbeta]
DECIPHERNDUFB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNDUFB1 
Mutations
ICGC Data PortalNDUFB1 
TCGA Data PortalNDUFB1 
Broad Tumor PortalNDUFB1
OASIS PortalNDUFB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNDUFB1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNDUFB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NDUFB1
DgiDB (Drug Gene Interaction Database)NDUFB1
DoCM (Curated mutations)NDUFB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NDUFB1 (select a term)
intoGenNDUFB1
Cancer3DNDUFB1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603837   
Orphanet
MedgenNDUFB1
Genetic Testing Registry NDUFB1
NextProtO75438 [Medical]
TSGene4707
GENETestsNDUFB1
Target ValidationNDUFB1
Huge Navigator NDUFB1 [HugePedia]
snp3D : Map Gene to Disease4707
BioCentury BCIQNDUFB1
ClinGenNDUFB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4707
Chemical/Pharm GKB GenePA31501
Clinical trialNDUFB1
Miscellaneous
canSAR (ICR)NDUFB1 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNDUFB1
EVEXNDUFB1
GoPubMedNDUFB1
iHOPNDUFB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:32:27 CEST 2017

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