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NDUFB2 (NADH:ubiquinone oxidoreductase subunit B2)

Identity

Alias_namesNADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2 (8kD, AGGG)
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
Alias_symbol (synonym)AGGG
CI-AGGG
Other alias
HGNC (Hugo) NDUFB2
LocusID (NCBI) 4708
Atlas_Id 56329
Location 7q34  [Link to chromosome band 7q34]
Location_base_pair Starts at 140696681 and ends at 140706646 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AGK (7q34) / NDUFB2 (7q34)DCP2 (5q22.2) / NDUFB2 (7q34)HS6ST2 (Xq26.2) / NDUFB2 (7q34)
KDM7A (7q34) / NDUFB2 (7q34)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NDUFB2   7697
Cards
Entrez_Gene (NCBI)NDUFB2  4708  NADH:ubiquinone oxidoreductase subunit B2
AliasesAGGG; CI-AGGG
GeneCards (Weizmann)NDUFB2
Ensembl hg19 (Hinxton)ENSG00000090266 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000090266 [Gene_View]  chr7:140696681-140706646 [Contig_View]  NDUFB2 [Vega]
ICGC DataPortalENSG00000090266
TCGA cBioPortalNDUFB2
AceView (NCBI)NDUFB2
Genatlas (Paris)NDUFB2
WikiGenes4708
SOURCE (Princeton)NDUFB2
Genetics Home Reference (NIH)NDUFB2
Genomic and cartography
GoldenPath hg38 (UCSC)NDUFB2  -     chr7:140696681-140706646 +  7q34   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NDUFB2  -     7q34   [Description]    (hg19-Feb_2009)
EnsemblNDUFB2 - 7q34 [CytoView hg19]  NDUFB2 - 7q34 [CytoView hg38]
Mapping of homologs : NCBINDUFB2 [Mapview hg19]  NDUFB2 [Mapview hg38]
OMIM603838   
Gene and transcription
Genbank (Entrez)AF050639 AF067166 BC001168 BC063026 CR542121
RefSeq transcript (Entrez)NM_004546
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NDUFB2
Cluster EST : UnigeneHs.655788 [ NCBI ]
CGAP (NCI)Hs.655788
Alternative Splicing GalleryENSG00000090266
Gene ExpressionNDUFB2 [ NCBI-GEO ]   NDUFB2 [ EBI - ARRAY_EXPRESS ]   NDUFB2 [ SEEK ]   NDUFB2 [ MEM ]
Gene Expression Viewer (FireBrowse)NDUFB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4708
GTEX Portal (Tissue expression)NDUFB2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95178   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95178  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95178
Splice isoforms : SwissVarO95178
PhosPhoSitePlusO95178
Domains : Interpro (EBI)NDUFB2   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)NDUFB2
DMDM Disease mutations4708
Blocks (Seattle)NDUFB2
SuperfamilyO95178
Human Protein AtlasENSG00000090266
Peptide AtlasO95178
HPRD11953
IPIIPI00028904   IPI00004872   IPI00946683   IPI00944982   IPI00947336   IPI00947220   IPI00945159   
Protein Interaction databases
DIP (DOE-UCLA)O95178
IntAct (EBI)O95178
FunCoupENSG00000090266
BioGRIDNDUFB2
STRING (EMBL)NDUFB2
ZODIACNDUFB2
Ontologies - Pathways
QuickGOO95178
Ontology : AmiGOmitochondrial inner membrane  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial electron transport, NADH to ubiquinone  mitochondrial electron transport, NADH to ubiquinone  NADH dehydrogenase (ubiquinone) activity  mitochondrial respiratory chain complex I assembly  
Ontology : EGO-EBImitochondrial inner membrane  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial electron transport, NADH to ubiquinone  mitochondrial electron transport, NADH to ubiquinone  NADH dehydrogenase (ubiquinone) activity  mitochondrial respiratory chain complex I assembly  
Pathways : KEGGOxidative phosphorylation    Non-alcoholic fatty liver disease (NAFLD)    Alzheimer's disease    Parkinson's disease    Huntington's disease   
NDEx NetworkNDUFB2
Atlas of Cancer Signalling NetworkNDUFB2
Wikipedia pathwaysNDUFB2
Orthology - Evolution
OrthoDB4708
GeneTree (enSembl)ENSG00000090266
Phylogenetic Trees/Animal Genes : TreeFamNDUFB2
HOVERGENO95178
HOGENOMO95178
Homologs : HomoloGeneNDUFB2
Homology/Alignments : Family Browser (UCSC)NDUFB2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNDUFB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NDUFB2
dbVarNDUFB2
ClinVarNDUFB2
1000_GenomesNDUFB2 
Exome Variant ServerNDUFB2
ExAC (Exome Aggregation Consortium)NDUFB2 (select the gene name)
Genetic variants : HAPMAP4708
Genomic Variants (DGV)NDUFB2 [DGVbeta]
DECIPHERNDUFB2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNDUFB2 
Mutations
ICGC Data PortalNDUFB2 
TCGA Data PortalNDUFB2 
Broad Tumor PortalNDUFB2
OASIS PortalNDUFB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNDUFB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNDUFB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NDUFB2
DgiDB (Drug Gene Interaction Database)NDUFB2
DoCM (Curated mutations)NDUFB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NDUFB2 (select a term)
intoGenNDUFB2
Cancer3DNDUFB2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603838   
Orphanet
MedgenNDUFB2
Genetic Testing Registry NDUFB2
NextProtO95178 [Medical]
TSGene4708
GENETestsNDUFB2
Target ValidationNDUFB2
Huge Navigator NDUFB2 [HugePedia]
snp3D : Map Gene to Disease4708
BioCentury BCIQNDUFB2
ClinGenNDUFB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4708
Chemical/Pharm GKB GenePA31503
Clinical trialNDUFB2
Miscellaneous
canSAR (ICR)NDUFB2 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNDUFB2
EVEXNDUFB2
GoPubMedNDUFB2
iHOPNDUFB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:01:23 CEST 2017

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