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NDUFC1 (NADH:ubiquinone oxidoreductase subunit C1)

Identity

Alias_namesNADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1 (6kD, KFYI)
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
Alias_symbol (synonym)KFYI
Other alias
HGNC (Hugo) NDUFC1
LocusID (NCBI) 4717
Atlas_Id 70780
Location 4q31.1  [Link to chromosome band 4q31]
Location_base_pair Starts at 139289917 and ends at 139301210 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NDUFC1   7705
Cards
Entrez_Gene (NCBI)NDUFC1  4717  NADH:ubiquinone oxidoreductase subunit C1
AliasesKFYI
GeneCards (Weizmann)NDUFC1
Ensembl hg19 (Hinxton)ENSG00000109390 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000109390 [Gene_View]  chr4:139289917-139301210 [Contig_View]  NDUFC1 [Vega]
ICGC DataPortalENSG00000109390
TCGA cBioPortalNDUFC1
AceView (NCBI)NDUFC1
Genatlas (Paris)NDUFC1
WikiGenes4717
SOURCE (Princeton)NDUFC1
Genetics Home Reference (NIH)NDUFC1
Genomic and cartography
GoldenPath hg38 (UCSC)NDUFC1  -     chr4:139289917-139301210 -  4q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NDUFC1  -     4q31.1   [Description]    (hg19-Feb_2009)
EnsemblNDUFC1 - 4q31.1 [CytoView hg19]  NDUFC1 - 4q31.1 [CytoView hg38]
Mapping of homologs : NCBINDUFC1 [Mapview hg19]  NDUFC1 [Mapview hg38]
OMIM603844   
Gene and transcription
Genbank (Entrez)AF047184 AF047435 AK023115 AK291147 BC101798
RefSeq transcript (Entrez)NM_001184986 NM_001184987 NM_001184988 NM_001184989 NM_001184990 NM_001184991 NM_002494
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NDUFC1
Cluster EST : UnigeneHs.84549 [ NCBI ]
CGAP (NCI)Hs.84549
Alternative Splicing GalleryENSG00000109390
Gene ExpressionNDUFC1 [ NCBI-GEO ]   NDUFC1 [ EBI - ARRAY_EXPRESS ]   NDUFC1 [ SEEK ]   NDUFC1 [ MEM ]
Gene Expression Viewer (FireBrowse)NDUFC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4717
GTEX Portal (Tissue expression)NDUFC1
Human Protein AtlasENSG00000109390-NDUFC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43677   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43677  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43677
Splice isoforms : SwissVarO43677
PhosPhoSitePlusO43677
Domains : Interpro (EBI)NDUFC1   
Domain families : Pfam (Sanger)NADH_dh_m_C1 (PF15088)   
Domain families : Pfam (NCBI)pfam15088   
Conserved Domain (NCBI)NDUFC1
DMDM Disease mutations4717
Blocks (Seattle)NDUFC1
SuperfamilyO43677
Human Protein Atlas [tissue]ENSG00000109390-NDUFC1 [tissue]
Peptide AtlasO43677
HPRD11959
IPIIPI00013461   
Protein Interaction databases
DIP (DOE-UCLA)O43677
IntAct (EBI)O43677
FunCoupENSG00000109390
BioGRIDNDUFC1
STRING (EMBL)NDUFC1
ZODIACNDUFC1
Ontologies - Pathways
QuickGOO43677
Ontology : AmiGOmitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain complex I  mitochondrial electron transport, NADH to ubiquinone  mitochondrial electron transport, NADH to ubiquinone  NADH dehydrogenase (ubiquinone) activity  integral component of membrane  mitochondrial respiratory chain complex I assembly  
Ontology : EGO-EBImitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain complex I  mitochondrial electron transport, NADH to ubiquinone  mitochondrial electron transport, NADH to ubiquinone  NADH dehydrogenase (ubiquinone) activity  integral component of membrane  mitochondrial respiratory chain complex I assembly  
Pathways : KEGGOxidative phosphorylation    Non-alcoholic fatty liver disease (NAFLD)    Alzheimer's disease    Parkinson's disease    Huntington's disease   
NDEx NetworkNDUFC1
Atlas of Cancer Signalling NetworkNDUFC1
Wikipedia pathwaysNDUFC1
Orthology - Evolution
OrthoDB4717
GeneTree (enSembl)ENSG00000109390
Phylogenetic Trees/Animal Genes : TreeFamNDUFC1
HOVERGENO43677
HOGENOMO43677
Homologs : HomoloGeneNDUFC1
Homology/Alignments : Family Browser (UCSC)NDUFC1
Gene fusions - Rearrangements
Fusion: Tumor Portal NDUFC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNDUFC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NDUFC1
dbVarNDUFC1
ClinVarNDUFC1
1000_GenomesNDUFC1 
Exome Variant ServerNDUFC1
ExAC (Exome Aggregation Consortium)ENSG00000109390
GNOMAD BrowserENSG00000109390
Genetic variants : HAPMAP4717
Genomic Variants (DGV)NDUFC1 [DGVbeta]
DECIPHERNDUFC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNDUFC1 
Mutations
ICGC Data PortalNDUFC1 
TCGA Data PortalNDUFC1 
Broad Tumor PortalNDUFC1
OASIS PortalNDUFC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNDUFC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNDUFC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NDUFC1
DgiDB (Drug Gene Interaction Database)NDUFC1
DoCM (Curated mutations)NDUFC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NDUFC1 (select a term)
intoGenNDUFC1
Cancer3DNDUFC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603844   
Orphanet
MedgenNDUFC1
Genetic Testing Registry NDUFC1
NextProtO43677 [Medical]
TSGene4717
GENETestsNDUFC1
Target ValidationNDUFC1
Huge Navigator NDUFC1 [HugePedia]
snp3D : Map Gene to Disease4717
BioCentury BCIQNDUFC1
ClinGenNDUFC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4717
Chemical/Pharm GKB GenePA31516
Clinical trialNDUFC1
Miscellaneous
canSAR (ICR)NDUFC1 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNDUFC1
EVEXNDUFC1
GoPubMedNDUFC1
iHOPNDUFC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:18:48 CET 2017

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