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NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2)

Identity

Alias_namesNADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2 (14.5kD, B14.5b)
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
Alias_symbol (synonym)B14.5b
HLC-1
Other aliasCI-B14.5b
NADHDH2
HGNC (Hugo) NDUFC2
LocusID (NCBI) 4718
Atlas_Id 52196
Location 11q14.1  [Link to chromosome band 11q14]
Location_base_pair Starts at 78068347 and ends at 78080219 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NDUFC2   7706
Cards
Entrez_Gene (NCBI)NDUFC2  4718  NADH:ubiquinone oxidoreductase subunit C2
AliasesB14.5b; CI-B14.5b; HLC-1; NADHDH2
GeneCards (Weizmann)NDUFC2
Ensembl hg19 (Hinxton)ENSG00000151366 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151366 [Gene_View]  chr11:78068347-78080219 [Contig_View]  NDUFC2 [Vega]
ICGC DataPortalENSG00000151366
TCGA cBioPortalNDUFC2
AceView (NCBI)NDUFC2
Genatlas (Paris)NDUFC2
WikiGenes4718
SOURCE (Princeton)NDUFC2
Genetics Home Reference (NIH)NDUFC2
Genomic and cartography
GoldenPath hg38 (UCSC)NDUFC2  -     chr11:78068347-78080219 -  11q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NDUFC2  -     11q14.1   [Description]    (hg19-Feb_2009)
EnsemblNDUFC2 - 11q14.1 [CytoView hg19]  NDUFC2 - 11q14.1 [CytoView hg38]
Mapping of homologs : NCBINDUFC2 [Mapview hg19]  NDUFC2 [Mapview hg38]
OMIM603845   
Gene and transcription
Genbank (Entrez)AF070652 AF087659 AF087899 AF369951 AF369952
RefSeq transcript (Entrez)NM_001204054 NM_001204055 NM_004549
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NDUFC2
Cluster EST : UnigeneHs.407860 [ NCBI ]
CGAP (NCI)Hs.407860
Alternative Splicing GalleryENSG00000151366
Gene ExpressionNDUFC2 [ NCBI-GEO ]   NDUFC2 [ EBI - ARRAY_EXPRESS ]   NDUFC2 [ SEEK ]   NDUFC2 [ MEM ]
Gene Expression Viewer (FireBrowse)NDUFC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4718
GTEX Portal (Tissue expression)NDUFC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95298   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95298  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95298
Splice isoforms : SwissVarO95298
PhosPhoSitePlusO95298
Domains : Interpro (EBI)NADH-UbQ_OxRdtase_b14.5b_su   
Domain families : Pfam (Sanger)NDUF_C2 (PF06374)   
Domain families : Pfam (NCBI)pfam06374   
Conserved Domain (NCBI)NDUFC2
DMDM Disease mutations4718
Blocks (Seattle)NDUFC2
SuperfamilyO95298
Human Protein AtlasENSG00000151366
Peptide AtlasO95298
HPRD11960
IPIIPI00029558   IPI00386441   IPI00979424   IPI00975925   
Protein Interaction databases
DIP (DOE-UCLA)O95298
IntAct (EBI)O95298
FunCoupENSG00000151366
BioGRIDNDUFC2
STRING (EMBL)NDUFC2
ZODIACNDUFC2
Ontologies - Pathways
QuickGOO95298
Ontology : AmiGOcytoplasm  mitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  plasma membrane  mitochondrial electron transport, NADH to ubiquinone  mitochondrial electron transport, NADH to ubiquinone  NADH dehydrogenase (ubiquinone) activity  integral component of membrane  mitochondrial respiratory chain complex I assembly  azurophil granule membrane  neutrophil degranulation  
Ontology : EGO-EBIcytoplasm  mitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  plasma membrane  mitochondrial electron transport, NADH to ubiquinone  mitochondrial electron transport, NADH to ubiquinone  NADH dehydrogenase (ubiquinone) activity  integral component of membrane  mitochondrial respiratory chain complex I assembly  azurophil granule membrane  neutrophil degranulation  
Pathways : KEGGOxidative phosphorylation    Non-alcoholic fatty liver disease (NAFLD)    Alzheimer's disease    Parkinson's disease    Huntington's disease   
NDEx NetworkNDUFC2
Atlas of Cancer Signalling NetworkNDUFC2
Wikipedia pathwaysNDUFC2
Orthology - Evolution
OrthoDB4718
GeneTree (enSembl)ENSG00000151366
Phylogenetic Trees/Animal Genes : TreeFamNDUFC2
HOVERGENO95298
HOGENOMO95298
Homologs : HomoloGeneNDUFC2
Homology/Alignments : Family Browser (UCSC)NDUFC2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNDUFC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NDUFC2
dbVarNDUFC2
ClinVarNDUFC2
1000_GenomesNDUFC2 
Exome Variant ServerNDUFC2
ExAC (Exome Aggregation Consortium)NDUFC2 (select the gene name)
Genetic variants : HAPMAP4718
Genomic Variants (DGV)NDUFC2 [DGVbeta]
DECIPHERNDUFC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNDUFC2 
Mutations
ICGC Data PortalNDUFC2 
TCGA Data PortalNDUFC2 
Broad Tumor PortalNDUFC2
OASIS PortalNDUFC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNDUFC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNDUFC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NDUFC2
DgiDB (Drug Gene Interaction Database)NDUFC2
DoCM (Curated mutations)NDUFC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NDUFC2 (select a term)
intoGenNDUFC2
Cancer3DNDUFC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603845   
Orphanet
MedgenNDUFC2
Genetic Testing Registry NDUFC2
NextProtO95298 [Medical]
TSGene4718
GENETestsNDUFC2
Huge Navigator NDUFC2 [HugePedia]
snp3D : Map Gene to Disease4718
BioCentury BCIQNDUFC2
ClinGenNDUFC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4718
Chemical/Pharm GKB GenePA31517
Clinical trialNDUFC2
Miscellaneous
canSAR (ICR)NDUFC2 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNDUFC2
EVEXNDUFC2
GoPubMedNDUFC2
iHOPNDUFC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:28:19 CEST 2017

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