Atlas of Genetics and Cytogenetics in Oncology and Haematology

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NDUFS3 (NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase))

Identity

Other namesCI-30
HGNC (Hugo) NDUFS3
LocusID (NCBI) 4722
Location 11p11.2
Location_base_pair Starts at 47600562 and ends at 47606115 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)NDUFS3   7710
Entrez_Gene (NCBI)NDUFS3  4722  NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
Cards
GeneCards (Weizmann)NDUFS3
Ensembl (Hinxton)ENSG00000213619 [Gene_View]  chr11:47600562-47606115 [Contig_View]  NDUFS3 [Vega]
AceView (NCBI)NDUFS3
Genatlas (Paris)NDUFS3
SOURCE (Stanford)NM_004551
Genomic and cartography
GoldenPath (UCSC)NDUFS3  -  11p11.2   chr11:47600562-47606115 +  11p11.2   [Description]    (hg19-Feb_2009)
EnsemblNDUFS3 - 11p11.2 [CytoView]
Mapping of homologs : NCBINDUFS3 [Mapview]
OMIM252010   256000   603846   
Gene and transcription
Genbank (Entrez)AA477836 AF067139 AF100743 AK223255 AK294167
RefSeq transcript (SRS)NM_004551
RefSeq transcript (Entrez)NM_004551
RefSeq genomic (SRS)AC_000143 NC_000011 NC_018922 NG_011946 NT_009237 NW_001838022 NW_004078070
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NG_011946 NT_009237 NW_001838022 NW_004078070
Consensus coding sequences : CCDS (NCBI)NDUFS3
Cluster EST : UnigeneHs.502528 [ SRS ] Hs.502528 [ NCBI ]
CGAP (NCI)Hs.502528
Alternative Splicing : Fast-db (Paris)GSHG0004806
Alternative Splicing GalleryENSG00000213619
Gene ExpressionNDUFS3 [ NCBI-GEO ]   NDUFS3 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75489 (SRS) O75489 (Uniprot)
NextProtO75489
With graphics : InterProO75489
Splice isoforms : SwissVarO75489(Swissvar)
Domaine pattern : Prosite (SRS)COMPLEX1_30K (PS00542)   
Domaine pattern : Prosite (Expaxy)COMPLEX1_30K (PS00542)   
Domains : Interpro (SRS)NADH_DH_suC    NADH_UbQ_OxRdtase_30kDa_su    NADH_UbQ_OxRdtase_CS   
Domains : Interpro (EBI)NADH_DH_suC    NADH_UbQ_OxRdtase_30kDa_su    NADH_UbQ_OxRdtase_CS   
Related proteins : CluSTrO75489
Domain families : Pfam (SRS)Complex1_30kDa (PF00329)   
Domain families : Pfam (Sanger)Complex1_30kDa (PF00329)   
Domain families : Pfam (NCBI)pfam00329   
Domain structure : Prodom (Prabi Lyon)NADH_UbQ_OxRdtase_30kDa_su (PD001581)   
DMDM4722
Blocks (Seattle)O75489
Human Protein AtlasENSG00000213619
HPRD10355
IPIIPI00025796   IPI00984253   IPI00982902   IPI00982388   IPI00983082   IPI00983169   
Protein Interaction databases
DIP (DOE-UCLA)O75489
IntAct (EBI)O75489
FunCoupENSG00000213619
REACTOMENDUFS3
Protein Interaction Database4722
BioGRIDNDUFS3
InParanoidO75489
Interologous Interaction database O75489
IntegromeDBNDUFS3
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)NDUFS3
SNP (GeneSNP Utah)NDUFS3
SNP : HGBaseNDUFS3
Genetic variants : HAPMAPNDUFS3
Somatic Mutations in Cancer : COSMICNDUFS3 
CONAN: Copy Number AnalysisNDUFS3 
Mutations and Diseases : HGMDNDUFS3
OMIM252010    256000    603846   
GENETests252010    256000    603846   
Disease Genetic AssociationNDUFS3
Huge Navigator NDUFS3 [HugePedia]  NDUFS3 [HugeCancerGEM]
Genomic VariantsNDUFS3  NDUFS3 [DGVbeta]
snp3D : Map Gene to Disease4722
General knowledge
Homologs : HomoloGeneNDUFS3
Homology/Alignments : Family Browser (UCSC)NDUFS3
Phylogenetic Trees/Animal Genes : TreeFamNDUFS3
Catalytic activity : Enzyme1.6.5.3 [ Enzyme-Expasy ]   1.6.5.3 [ Enzyme-SRS ]   1.6.5.3 [ IntEnz-EBI ]   1.6.5.3 [ BRENDA ]   1.6.5.3 [ KEGG ]   
Chemical/Protein Interactions : CTD4722
Chemical/Pharm GKB GenePA31520
Clinical trialNDUFS3
Cancer Resource (Charite)ENSG00000213619
Ontology : AmiGONADH dehydrogenase activity  protein binding  mitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial electron transport, NADH to ubiquinone  induction of apoptosis  NADH dehydrogenase (ubiquinone) activity  electron carrier activity  respiratory electron transport chain  negative regulation of cell growth  mitochondrial membrane  small molecule metabolic process  reactive oxygen species metabolic process  
Ontology : EGO-EBINADH dehydrogenase activity  protein binding  mitochondrion  mitochondrial inner membrane  mitochondrial respiratory chain complex I  mitochondrial respiratory chain complex I  mitochondrial electron transport, NADH to ubiquinone  induction of apoptosis  NADH dehydrogenase (ubiquinone) activity  electron carrier activity  respiratory electron transport chain  negative regulation of cell growth  mitochondrial membrane  small molecule metabolic process  reactive oxygen species metabolic process  
Pathways : KEGGOxidative phosphorylation
Other databases
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
PubGeneNDUFS3
iHOPNDUFS3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:31:17 CEST 2013
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