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NECTIN3 (nectin cell adhesion molecule 3)

Identity

Alias_namesPVRL3
poliovirus receptor-related 3
Alias_symbol (synonym)nectin-3
PPR3
PVRR3
DKFZP566B0846
CDw113
CD113
Other aliasCDW113
NECTIN-3
PRR3
HGNC (Hugo) NECTIN3
LocusID (NCBI) 25945
Atlas_Id 55656
Location 3q13.13  [Link to chromosome band 3q13]
Location_base_pair Starts at 111071759 and ends at 111137560 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AGFG1 (2q36.3) / NECTIN3 (3q13.13)NECTIN3 (3q13.13) / NECTIN3 (3q13.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NECTIN3   17664
Cards
Entrez_Gene (NCBI)NECTIN3  25945  nectin cell adhesion molecule 3
AliasesCD113; CDW113; NECTIN-3; PPR3; 
PRR3; PVRL3; PVRR3
GeneCards (Weizmann)NECTIN3
Ensembl hg19 (Hinxton)ENSG00000177707 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000177707 [Gene_View]  chr3:111071759-111137560 [Contig_View]  NECTIN3 [Vega]
ICGC DataPortalENSG00000177707
TCGA cBioPortalNECTIN3
AceView (NCBI)NECTIN3
Genatlas (Paris)NECTIN3
WikiGenes25945
SOURCE (Princeton)NECTIN3
Genetics Home Reference (NIH)NECTIN3
Genomic and cartography
GoldenPath hg38 (UCSC)NECTIN3  -     chr3:111071759-111137560 +  3q13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NECTIN3  -     3q13.13   [Description]    (hg19-Feb_2009)
EnsemblNECTIN3 - 3q13.13 [CytoView hg19]  NECTIN3 - 3q13.13 [CytoView hg38]
Mapping of homologs : NCBINECTIN3 [Mapview hg19]  NECTIN3 [Mapview hg38]
OMIM607147   
Gene and transcription
Genbank (Entrez)AA555086 AF282874 AK075105 AK125090 AL050071
RefSeq transcript (Entrez)NM_001243286 NM_001243288 NM_015480
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NECTIN3
Cluster EST : UnigeneHs.656767 [ NCBI ]
CGAP (NCI)Hs.656767
Alternative Splicing GalleryENSG00000177707
Gene ExpressionNECTIN3 [ NCBI-GEO ]   NECTIN3 [ EBI - ARRAY_EXPRESS ]   NECTIN3 [ SEEK ]   NECTIN3 [ MEM ]
Gene Expression Viewer (FireBrowse)NECTIN3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25945
GTEX Portal (Tissue expression)NECTIN3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NQS3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NQS3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NQS3
Splice isoforms : SwissVarQ9NQS3
PhosPhoSitePlusQ9NQS3
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)CD80_C2-set    Ig-like_dom    Ig-like_fold    Ig_sub    Ig_V-set    Nectin-3   
Domain families : Pfam (Sanger)C2-set_2 (PF08205)    V-set (PF07686)   
Domain families : Pfam (NCBI)pfam08205    pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)NECTIN3
DMDM Disease mutations25945
Blocks (Seattle)NECTIN3
PDB (SRS)4FOM   
PDB (PDBSum)4FOM   
PDB (IMB)4FOM   
PDB (RSDB)4FOM   
Structural Biology KnowledgeBase4FOM   
SCOP (Structural Classification of Proteins)4FOM   
CATH (Classification of proteins structures)4FOM   
SuperfamilyQ9NQS3
Human Protein AtlasENSG00000177707
Peptide AtlasQ9NQS3
HPRD08454
IPIIPI00022959   IPI00736191   IPI00301239   IPI00946956   IPI00946889   IPI00947021   IPI00947123   IPI00945067   
Protein Interaction databases
DIP (DOE-UCLA)Q9NQS3
IntAct (EBI)Q9NQS3
FunCoupENSG00000177707
BioGRIDNECTIN3
STRING (EMBL)NECTIN3
ZODIACNECTIN3
Ontologies - Pathways
QuickGOQ9NQS3
Ontology : AmiGOlens morphogenesis in camera-type eye  receptor activity  receptor binding  protein binding  plasma membrane  plasma membrane  integral component of plasma membrane  cell-cell adherens junction  homophilic cell adhesion via plasma membrane adhesion molecules  homophilic cell adhesion via plasma membrane adhesion molecules  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  spermatid development  cell recognition  fertilization  single organismal cell-cell adhesion  adherens junction organization  protein homodimerization activity  protein homodimerization activity  apical junction complex  cell-cell contact zone  postsynaptic membrane  protein heterodimerization activity  cell adhesion molecule binding  retina morphogenesis in camera-type eye  protein localization to cell junction  
Ontology : EGO-EBIlens morphogenesis in camera-type eye  receptor activity  receptor binding  protein binding  plasma membrane  plasma membrane  integral component of plasma membrane  cell-cell adherens junction  homophilic cell adhesion via plasma membrane adhesion molecules  homophilic cell adhesion via plasma membrane adhesion molecules  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  spermatid development  cell recognition  fertilization  single organismal cell-cell adhesion  adherens junction organization  protein homodimerization activity  protein homodimerization activity  apical junction complex  cell-cell contact zone  postsynaptic membrane  protein heterodimerization activity  cell adhesion molecule binding  retina morphogenesis in camera-type eye  protein localization to cell junction  
NDEx NetworkNECTIN3
Atlas of Cancer Signalling NetworkNECTIN3
Wikipedia pathwaysNECTIN3
Orthology - Evolution
OrthoDB25945
GeneTree (enSembl)ENSG00000177707
Phylogenetic Trees/Animal Genes : TreeFamNECTIN3
HOVERGENQ9NQS3
HOGENOMQ9NQS3
Homologs : HomoloGeneNECTIN3
Homology/Alignments : Family Browser (UCSC)NECTIN3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNECTIN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NECTIN3
dbVarNECTIN3
ClinVarNECTIN3
1000_GenomesNECTIN3 
Exome Variant ServerNECTIN3
ExAC (Exome Aggregation Consortium)NECTIN3 (select the gene name)
Genetic variants : HAPMAP25945
Genomic Variants (DGV)NECTIN3 [DGVbeta]
DECIPHERNECTIN3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNECTIN3 
Mutations
ICGC Data PortalNECTIN3 
TCGA Data PortalNECTIN3 
Broad Tumor PortalNECTIN3
OASIS PortalNECTIN3 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDNECTIN3
BioMutasearch NECTIN3
DgiDB (Drug Gene Interaction Database)NECTIN3
DoCM (Curated mutations)NECTIN3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NECTIN3 (select a term)
intoGenNECTIN3
Cancer3DNECTIN3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607147   
Orphanet
MedgenNECTIN3
Genetic Testing Registry NECTIN3
NextProtQ9NQS3 [Medical]
TSGene25945
GENETestsNECTIN3
Huge Navigator NECTIN3 [HugePedia]
snp3D : Map Gene to Disease25945
BioCentury BCIQNECTIN3
ClinGenNECTIN3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25945
Chemical/Pharm GKB GenePA134969621
Clinical trialNECTIN3
Miscellaneous
canSAR (ICR)NECTIN3 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNECTIN3
EVEXNECTIN3
GoPubMedNECTIN3
iHOPNECTIN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:28:22 CEST 2017

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