NEDD8 (neural precursor cell expressed, developmentally down-regulated 8)

Identity

Other names	FLJ43224
	MGC104393
	MGC125896
	MGC125897
	Nedd-8
HGNC	NEDD8
Location	14q12
Location_base_pair	Starts at 23755897 and ends at 23771416 bp from pter (hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	NEDD8   7732
Entrez_Gene	NEDD8  4738  neural precursor cell expressed, developmentally down-regulated 8
	Cards
GeneCards	NEDD8
Ensembl	NEDD8 [Search_View]   ENSG00000129559 [Gene_View]
Genatlas	NEDD8
GeneLynx	NEDD8
eGenome	NEDD8
euGene	4738
	Genomic and cartography
GoldenPath	NEDD8  -  14q12   chr14:23755897-23771416 -  14q12   [Description]    (hg18-March_2006)
Ensembl	NEDD8 - 14q12 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	NEDD8
	Gene and transcription
Genbank	AK125214 [ ENTREZ ]
Genbank	BC038290 [ ENTREZ ]
Genbank	BC064899 [ ENTREZ ]
Genbank	BC104200 [ ENTREZ ]
Genbank	BC104201 [ ENTREZ ]
RefSeq	NM_006156 [ SRS ]    NM_006156 [ ENTREZ ]
RefSeq	AC_000057 [ SRS ]    AC_000057 [ ENTREZ ]
RefSeq	AC_000146 [ SRS ]    AC_000146 [ ENTREZ ]
RefSeq	NC_000014 [ SRS ]    NC_000014 [ ENTREZ ]
RefSeq	NT_026437 [ SRS ]    NT_026437 [ ENTREZ ]
RefSeq	NW_001838110 [ SRS ]    NW_001838110 [ ENTREZ ]
RefSeq	NW_925539 [ SRS ]    NW_925539 [ ENTREZ ]
AceView	NEDD8 AceView - NCBI
Unigene	Hs.531064 [ SRS ]    Hs.531064 [ NCBI ]     HS531064 [ spliceNest ]
Fast-db	103 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q15843 [ SRS]    Q15843 [ EXPASY ]     Q15843 [ INTERPRO ]     Q15843 [ UNIPROT ]
Prosite	PS00299 UBIQUITIN_1 [ SRS ]    PS00299 UBIQUITIN_1 [ Expasy ]
Prosite	PS50053 UBIQUITIN_2 [ SRS ]    PS50053 UBIQUITIN_2 [ Expasy ]
Interpro	IPR000626 Ubiquitin [ SRS ]    IPR000626 Ubiquitin [ EBI ]
CluSTr	Q15843
Pfam	PF00240 ubiquitin [ SRS ]    PF00240 ubiquitin [ Sanger ]    pfam00240 [ NCBI-CDD ]
Smart	SM00213 UBQ [EMBL]
Blocks	Q15843
PDB	1NDD [ SRS ]    1NDD [ PdbSum ],   1NDD [ IMB ]   1NDD [ RSDB ]
PDB	1R4M [ SRS ]    1R4M [ PdbSum ],   1R4M [ IMB ]   1R4M [ RSDB ]
PDB	1R4N [ SRS ]    1R4N [ PdbSum ],   1R4N [ IMB ]   1R4N [ RSDB ]
PDB	1XT9 [ SRS ]    1XT9 [ PdbSum ],   1XT9 [ IMB ]   1XT9 [ RSDB ]
PDB	2BKR [ SRS ]    2BKR [ PdbSum ],   2BKR [ IMB ]   2BKR [ RSDB ]
PDB	2NVU [ SRS ]    2NVU [ PdbSum ],   2NVU [ IMB ]   2NVU [ RSDB ]
HPRD	04412
	Protein Interaction databases
DIP	Q15843
IntAct	Q15843
	Polymorphism : SNP, mutations, diseases
OMIM	603171    [ map ]
GENECLINICS	603171
SNP	NEDD8 [dbSNP-NCBI]
SNP	NM_006156 [SNP-NCI]
SNP	NEDD8 [GeneSNPs - Utah]  NEDD8] [HGBASE - SRS]
HAPMAP	NEDD8 [HAPMAP]
COSMIC	NEDD8 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	NEDD8
	General knowledge
Family Browser	NEDD8 [UCSC Family Browser]
SOURCE	NM_006156
SMD	Hs.531064
SAGE	Hs.531064
GO	protein binding [Amigo]  protein binding
GO	nucleus [Amigo]  nucleus
GO	protein modification process [Amigo]  protein modification process
GO	proteolysis [Amigo]  proteolysis
GO	ubiquitin-dependent protein catabolic process [Amigo]  ubiquitin-dependent protein catabolic process
GO	anatomical structure morphogenesis [Amigo]  anatomical structure morphogenesis
BIOCARTA	Regulation of p27 Phosphorylation during Cell Cycle Progression    [Genes]
PubGene	NEDD8
TreeFam	NEDD8
CTD	4738 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	NEDD8 Related clones (RZPD - Berlin)
	PubMed
PubMed	54 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 11 13:23:03 2008