NEGR1 (neuronal growth regulator 1)

2009-11-01  

Identity

HGNC
LOCATION
1p31.1
LOCUSID
ALIAS
DMML2433,IGLON4,KILON,Ntra
FUSION GENES

Other Information

Locus ID:

NCBI: 257194
MIM: 613173
HGNC: 17302
Ensembl: ENSG00000172260

Variants:

dbSNP: 257194
ClinVar: 257194
TCGA: ENSG00000172260
COSMIC: NEGR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172260ENST00000306821Q7Z3B1
ENSG00000172260ENST00000357731Q7Z3B1

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Cell adhesion molecules (CAMs)KEGGko04514
Cell adhesion molecules (CAMs)KEGGhsa04514
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteinsREACTOMER-HSA-163125

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
190792612009Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.700
274799092016Identification of 15 genetic loci associated with risk of major depression in individuals of European descent.170
191643862009Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden.104
289694422018Psychiatric Genomics: An Update and an Agenda.88
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
196924902009Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference.77
198121712010Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies.74
205208482010Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth.70
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
207245812010Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies.47

Citation

Dessen P

NEGR1 (neuronal growth regulator 1)

Atlas Genet Cytogenet Oncol Haematol. 2009-11-01

Online version: http://atlasgeneticsoncology.org/gene/51177/negr1