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NEIL3 (nei like DNA glycosylase 3)

Identity

Alias_namesGRF-type containing 3
Alias_symbol (synonym)FLJ10858
hFPG2
FPG2
hNEI3
ZGRF3
HGNC (Hugo) NEIL3
LocusID (NCBI) 55247
Atlas_Id 43003
Location 4q34.3  [Link to chromosome band 4q34]
Location_base_pair Starts at 178230991 and ends at 178284092 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NEIL3   24573
Cards
Entrez_Gene (NCBI)NEIL3  55247  nei like DNA glycosylase 3
AliasesFGP2; FPG2; NEI3; ZGRF3; 
hFPG2; hNEI3
GeneCards (Weizmann)NEIL3
Ensembl hg19 (Hinxton)ENSG00000109674 [Gene_View]  chr4:178230991-178284092 [Contig_View]  NEIL3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000109674 [Gene_View]  chr4:178230991-178284092 [Contig_View]  NEIL3 [Vega]
ICGC DataPortalENSG00000109674
TCGA cBioPortalNEIL3
AceView (NCBI)NEIL3
Genatlas (Paris)NEIL3
WikiGenes55247
SOURCE (Princeton)NEIL3
Genetics Home Reference (NIH)NEIL3
Genomic and cartography
GoldenPath hg19 (UCSC)NEIL3  -     chr4:178230991-178284092 +  4q34.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NEIL3  -     4q34.3   [Description]    (hg38-Dec_2013)
EnsemblNEIL3 - 4q34.3 [CytoView hg19]  NEIL3 - 4q34.3 [CytoView hg38]
Mapping of homologs : NCBINEIL3 [Mapview hg19]  NEIL3 [Mapview hg38]
OMIM608934   
Gene and transcription
Genbank (Entrez)AB079071 AI419161 AK001720 AK307692 BC025954
RefSeq transcript (Entrez)NM_018248
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)NEIL3
Cluster EST : UnigeneHs.405467 [ NCBI ]
CGAP (NCI)Hs.405467
Alternative Splicing GalleryENSG00000109674
Gene ExpressionNEIL3 [ NCBI-GEO ]   NEIL3 [ EBI - ARRAY_EXPRESS ]   NEIL3 [ SEEK ]   NEIL3 [ MEM ]
Gene Expression Viewer (FireBrowse)NEIL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55247
GTEX Portal (Tissue expression)NEIL3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TAT5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TAT5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TAT5
Splice isoforms : SwissVarQ8TAT5
Catalytic activity : Enzyme3.2.2.- [ Enzyme-Expasy ]   3.2.2.-3.2.2.- [ IntEnz-EBI ]   3.2.2.- [ BRENDA ]   3.2.2.- [ KEGG ]   
PhosPhoSitePlusQ8TAT5
Domaine pattern : Prosite (Expaxy)FPG_CAT (PS51068)    ZF_FPG_1 (PS01242)    ZF_FPG_2 (PS51066)    ZF_RANBP2_1 (PS01358)    ZF_RANBP2_2 (PS50199)   
Domains : Interpro (EBI)DNA_glyclase/AP_lyase_DNA-bd    DNA_glyclase_Znf_dom_DNA_BS    FPG_cat    Ribosomal_S13-like_H2TH    Znf_DNA_glyclase/AP_lyase    Znf_GRF    Znf_RanBP2   
Domain families : Pfam (Sanger)H2TH (PF06831)    zf-GRF (PF06839)    zf-RanBP (PF00641)   
Domain families : Pfam (NCBI)pfam06831    pfam06839    pfam00641   
Domain families : Smart (EMBL)ZnF_RBZ (SM00547)  
Conserved Domain (NCBI)NEIL3
DMDM Disease mutations55247
Blocks (Seattle)NEIL3
SuperfamilyQ8TAT5
Human Protein AtlasENSG00000109674
Peptide AtlasQ8TAT5
HPRD16407
IPIIPI00303135   IPI00964674   
Protein Interaction databases
DIP (DOE-UCLA)Q8TAT5
IntAct (EBI)Q8TAT5
FunCoupENSG00000109674
BioGRIDNEIL3
STRING (EMBL)NEIL3
ZODIACNEIL3
Ontologies - Pathways
QuickGOQ8TAT5
Ontology : AmiGObubble DNA binding  damaged DNA binding  double-stranded DNA binding  single-stranded DNA binding  DNA-(apurinic or apyrimidinic site) lyase activity  nucleus  nucleoplasm  base-excision repair  base-excision repair  nucleotide-excision repair  zinc ion binding  DNA N-glycosylase activity  DNA N-glycosylase activity  
Ontology : EGO-EBIbubble DNA binding  damaged DNA binding  double-stranded DNA binding  single-stranded DNA binding  DNA-(apurinic or apyrimidinic site) lyase activity  nucleus  nucleoplasm  base-excision repair  base-excision repair  nucleotide-excision repair  zinc ion binding  DNA N-glycosylase activity  DNA N-glycosylase activity  
Pathways : KEGGBase excision repair   
NDEx NetworkNEIL3
Atlas of Cancer Signalling NetworkNEIL3
Wikipedia pathwaysNEIL3
Orthology - Evolution
OrthoDB55247
GeneTree (enSembl)ENSG00000109674
Phylogenetic Trees/Animal Genes : TreeFamNEIL3
HOVERGENQ8TAT5
HOGENOMQ8TAT5
Homologs : HomoloGeneNEIL3
Homology/Alignments : Family Browser (UCSC)NEIL3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNEIL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NEIL3
dbVarNEIL3
ClinVarNEIL3
1000_GenomesNEIL3 
Exome Variant ServerNEIL3
ExAC (Exome Aggregation Consortium)NEIL3 (select the gene name)
Genetic variants : HAPMAP55247
Genomic Variants (DGV)NEIL3 [DGVbeta]
DECIPHER (Syndromes)4:178230991-178284092  ENSG00000109674
CONAN: Copy Number AnalysisNEIL3 
Mutations
ICGC Data PortalNEIL3 
TCGA Data PortalNEIL3 
Broad Tumor PortalNEIL3
OASIS PortalNEIL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNEIL3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNEIL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NEIL3
DgiDB (Drug Gene Interaction Database)NEIL3
DoCM (Curated mutations)NEIL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NEIL3 (select a term)
intoGenNEIL3
Cancer3DNEIL3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608934   
Orphanet
MedgenNEIL3
Genetic Testing Registry NEIL3
NextProtQ8TAT5 [Medical]
TSGene55247
GENETestsNEIL3
Huge Navigator NEIL3 [HugePedia]
snp3D : Map Gene to Disease55247
BioCentury BCIQNEIL3
ClinGenNEIL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55247
Chemical/Pharm GKB GenePA134889634
Clinical trialNEIL3
Miscellaneous
canSAR (ICR)NEIL3 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNEIL3
EVEXNEIL3
GoPubMedNEIL3
iHOPNEIL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Nov 18 19:45:42 CET 2016

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