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NEK11 (NIMA-related kinase 11)

Identity

Other names-
HGNC (Hugo) NEK11
LocusID (NCBI) 79858
Location 3q22.1
Location_base_pair Starts at 130745694 and ends at 131069309 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)NEK11   18593
Entrez_Gene (NCBI)NEK11  79858  NIMA-related kinase 11
Cards
GeneCards (Weizmann)NEK11
Ensembl (Hinxton)ENSG00000114670 [Gene_View]  chr3:130745694-131069309 [Contig_View]  NEK11 [Vega]
AceView (NCBI)NEK11
Genatlas (Paris)NEK11
SOURCE (Stanford)NM_001146003 NM_024800 NM_145910
Genomic and cartography
GoldenPath (UCSC)NEK11  -  3q22.1   chr3:130745694-131069309 +  3q22.1   [Description]    (hg19-Feb_2009)
EnsemblNEK11 - 3q22.1 [CytoView]
Mapping of homologs : NCBINEK11 [Mapview]
OMIM609779   
Gene and transcription
Genbank (Entrez)AB071996 AB071997 AK027148 AK123021 AK293261
RefSeq transcript (SRS)NM_001146003 NM_024800 NM_145910
RefSeq transcript (Entrez)NM_001146003 NM_024800 NM_145910
RefSeq genomic (SRS)AC_000135 NC_000003 NC_018914 NG_029225 NT_005612 NW_001838884 NW_004078013
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NG_029225 NT_005612 NW_001838884 NW_004078013
Consensus coding sequences : CCDS (NCBI)NEK11
Cluster EST : UnigeneHs.657336 [ SRS ] Hs.657336 [ NCBI ]
CGAP (NCI)Hs.657336
Alternative Splicing : Fast-db (Paris)GSHG0021155
Alternative Splicing GalleryENSG00000114670
Gene ExpressionNEK11 [ NCBI-GEO ]   NEK11 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NG66 (SRS) Q8NG66 (Uniprot)
NextProtQ8NG66
With graphics : InterProQ8NG66
Splice isoforms : SwissVarQ8NG66(Swissvar)
Domaine pattern : Prosite (SRS)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (SRS)Kinase-like_dom    Prot_kinase_cat_dom    Ser/Thr_dual-sp_kinase_dom    Ser/Thr_kinase_AS   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_cat_dom    Ser/Thr_dual-sp_kinase_dom    Ser/Thr_kinase_AS   
Related proteins : CluSTrQ8NG66
Domain families : Pfam (SRS)Pkinase (PF00069)   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
DMDM79858
Blocks (Seattle)Q8NG66
Human Protein AtlasENSG00000114670
HPRD14821
IPIIPI00745916   IPI00745302   IPI00398836   IPI00789673   IPI00788917   IPI00909435   IPI00965297   IPI00966497   
Protein Interaction databases
DIP (DOE-UCLA)Q8NG66
IntAct (EBI)Q8NG66
FunCoupENSG00000114670
REACTOMENEK11
Protein Interaction Database79858
BioGRIDNEK11
InParanoidQ8NG66
Interologous Interaction database Q8NG66
IntegromeDBNEK11
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)NEK11
SNP (GeneSNP Utah)NEK11
SNP : HGBaseNEK11
Genetic variants : HAPMAPNEK11
Somatic Mutations in Cancer : COSMICNEK11 
CONAN: Copy Number AnalysisNEK11 
Mutations and Diseases : HGMDNEK11
OMIM609779   
GENETests609779   
Disease Genetic AssociationNEK11
Huge Navigator NEK11 [HugePedia]  NEK11 [HugeCancerGEM]
Genomic VariantsNEK11  NEK11 [DGVbeta]
ClinVarNEK11
snp3D : Map Gene to Disease79858
General knowledge
Homologs : HomoloGeneNEK11
Homology/Alignments : Family Browser (UCSC)NEK11
Phylogenetic Trees/Animal Genes : TreeFamNEK11
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.1 [ Enzyme-SRS ]   2.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
Chemical/Protein Interactions : CTD79858
Chemical/Pharm GKB GenePA38595
Clinical trialNEK11
Cancer Resource (Charite)ENSG00000114670
Ontology : AmiGOprotein serine/threonine kinase activity  protein binding  ATP binding  nucleus  nucleolus  nucleolus  protein phosphorylation  intracellular protein kinase cascade  G2 DNA damage checkpoint  intra-S DNA damage checkpoint  metal ion binding  
Ontology : EGO-EBIprotein serine/threonine kinase activity  protein binding  ATP binding  nucleus  nucleolus  nucleolus  protein phosphorylation  intracellular protein kinase cascade  G2 DNA damage checkpoint  intra-S DNA damage checkpoint  metal ion binding  
Other databases
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
PubGeneNEK11
iHOPNEK11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:48:30 CEST 2013
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