NEK5 (NIMA related kinase 5)

2006-10-01  

Identity

HGNC
LOCATION
13q14.3
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 341676
MIM: 616731
HGNC: 7748
Ensembl: ENSG00000197168

Variants:

dbSNP: 341676
ClinVar: 341676
TCGA: ENSG00000197168
COSMIC: NEK5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197168ENST00000355568Q6P3R8
ENSG00000197168ENST00000465811E9PIX7
ENSG00000197168ENST00000617045Q6P3R8
ENSG00000197168ENST00000647945A0A3B3ITQ6
ENSG00000197168ENST00000652119A0A494C168

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
365505482022Identification of biological pathways and processes regulated by NEK5 in breast epithelial cells via an integrated proteomic approach.3
365505482022Identification of biological pathways and processes regulated by NEK5 in breast epithelial cells via an integrated proteomic approach.3
335478672021NEK5 interacts with LonP1 and its kinase activity is essential for the regulation of mitochondrial functions and mtDNA maintenance.5
337495482021Targeting Never-In-Mitosis-A Related Kinase 5 in Cancer: A Review.3
341969022021NEK5 activity regulates the mesenchymal and migratory phenotype in breast cancer cells.8
335478672021NEK5 interacts with LonP1 and its kinase activity is essential for the regulation of mitochondrial functions and mtDNA maintenance.5
337495482021Targeting Never-In-Mitosis-A Related Kinase 5 in Cancer: A Review.3
341969022021NEK5 activity regulates the mesenchymal and migratory phenotype in breast cancer cells.8
319068782020Expression of the NEK family in normal and cancer tissue: an immunohistochemical study.21
321966012020Knockdown of lncRNA XIST inhibits hypoxia-induced glycolysis, migration and invasion through regulating miR-381-3p/NEK5 axis in nasopharyngeal carcinoma.12
319068782020Expression of the NEK family in normal and cancer tissue: an immunohistochemical study.21
321966012020Knockdown of lncRNA XIST inhibits hypoxia-induced glycolysis, migration and invasion through regulating miR-381-3p/NEK5 axis in nasopharyngeal carcinoma.12
306759232019NEK5 promotes breast cancer cell proliferation through up-regulation of Cyclin A2.16
310909632019NEK5 interacts with topoisomerase IIβ and is involved in the DNA damage response induced by etoposide.12
306759232019NEK5 promotes breast cancer cell proliferation through up-regulation of Cyclin A2.16

Citation

Dessen P

NEK5 (NIMA related kinase 5)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43373/nek5