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NEK9 (NIMA related kinase 9)

Identity

Alias_namesNIMA (never in mitosis gene a)- related kinase 9
Alias_symbol (synonym)Nek8
NERCC
DKFZp434D0935
MGC16714
Other aliasNERCC1
HGNC (Hugo) NEK9
LocusID (NCBI) 91754
Atlas_Id 43377
Location 14q24.3  [Link to chromosome band 14q24]
Location_base_pair Starts at 75548818 and ends at 75593778 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
NEK9 (14q24.3) / NEK9 (14q24.3)SRF (6p21.1) / NEK9 (14q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NEK9   18591
Cards
Entrez_Gene (NCBI)NEK9  91754  NIMA related kinase 9
AliasesNERCC; NERCC1; Nek8
GeneCards (Weizmann)NEK9
Ensembl hg19 (Hinxton)ENSG00000119638 [Gene_View]  chr14:75548818-75593778 [Contig_View]  NEK9 [Vega]
Ensembl hg38 (Hinxton)ENSG00000119638 [Gene_View]  chr14:75548818-75593778 [Contig_View]  NEK9 [Vega]
ICGC DataPortalENSG00000119638
TCGA cBioPortalNEK9
AceView (NCBI)NEK9
Genatlas (Paris)NEK9
WikiGenes91754
SOURCE (Princeton)NEK9
Genetics Home Reference (NIH)NEK9
Genomic and cartography
GoldenPath hg19 (UCSC)NEK9  -     chr14:75548818-75593778 -  14q24.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NEK9  -     14q24.3   [Description]    (hg38-Dec_2013)
EnsemblNEK9 - 14q24.3 [CytoView hg19]  NEK9 - 14q24.3 [CytoView hg38]
Mapping of homologs : NCBINEK9 [Mapview hg19]  NEK9 [Mapview hg38]
OMIM609798   
Gene and transcription
Genbank (Entrez)AB082526 AK128693 AL117502 AL832633 AL833036
RefSeq transcript (Entrez)NM_033116
RefSeq genomic (Entrez)NC_000014 NC_018925 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)NEK9
Cluster EST : UnigeneHs.7200 [ NCBI ]
CGAP (NCI)Hs.7200
Alternative Splicing GalleryENSG00000119638
Gene ExpressionNEK9 [ NCBI-GEO ]   NEK9 [ EBI - ARRAY_EXPRESS ]   NEK9 [ SEEK ]   NEK9 [ MEM ]
Gene Expression Viewer (FireBrowse)NEK9 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)91754
GTEX Portal (Tissue expression)NEK9
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TD19   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TD19  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TD19
Splice isoforms : SwissVarQ8TD19
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
PhosPhoSitePlusQ8TD19
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)    RCC1_3 (PS50012)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    RCC1/BLIP-II    Reg_chr_condens    Ser/Thr_dual-sp_kinase    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)    RCC1 (PF00415)   
Domain families : Pfam (NCBI)pfam00069    pfam00415   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)NEK9
DMDM Disease mutations91754
Blocks (Seattle)NEK9
PDB (SRS)3ZKE    3ZKF   
PDB (PDBSum)3ZKE    3ZKF   
PDB (IMB)3ZKE    3ZKF   
PDB (RSDB)3ZKE    3ZKF   
Structural Biology KnowledgeBase3ZKE    3ZKF   
SCOP (Structural Classification of Proteins)3ZKE    3ZKF   
CATH (Classification of proteins structures)3ZKE    3ZKF   
SuperfamilyQ8TD19
Human Protein AtlasENSG00000119638
Peptide AtlasQ8TD19
HPRD11386
IPIIPI00301609   IPI01014019   IPI01025959   IPI01026055   IPI01025685   IPI01025780   
Protein Interaction databases
DIP (DOE-UCLA)Q8TD19
IntAct (EBI)Q8TD19
FunCoupENSG00000119638
BioGRIDNEK9
STRING (EMBL)NEK9
ZODIACNEK9
Ontologies - Pathways
QuickGOQ8TD19
Ontology : AmiGOprotein serine/threonine kinase activity  protein binding  ATP binding  nucleus  cytoplasm  centrosome  cytosol  protein phosphorylation  microtubule-based process  chromosome segregation  mitotic nuclear division  mitotic nuclear envelope disassembly  protein kinase binding  metal ion binding  cell division  
Ontology : EGO-EBIprotein serine/threonine kinase activity  protein binding  ATP binding  nucleus  cytoplasm  centrosome  cytosol  protein phosphorylation  microtubule-based process  chromosome segregation  mitotic nuclear division  mitotic nuclear envelope disassembly  protein kinase binding  metal ion binding  cell division  
NDEx NetworkNEK9
Atlas of Cancer Signalling NetworkNEK9
Wikipedia pathwaysNEK9
Orthology - Evolution
OrthoDB91754
GeneTree (enSembl)ENSG00000119638
Phylogenetic Trees/Animal Genes : TreeFamNEK9
HOVERGENQ8TD19
HOGENOMQ8TD19
Homologs : HomoloGeneNEK9
Homology/Alignments : Family Browser (UCSC)NEK9
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNEK9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NEK9
dbVarNEK9
ClinVarNEK9
1000_GenomesNEK9 
Exome Variant ServerNEK9
ExAC (Exome Aggregation Consortium)NEK9 (select the gene name)
Genetic variants : HAPMAP91754
Genomic Variants (DGV)NEK9 [DGVbeta]
DECIPHER (Syndromes)14:75548818-75593778  ENSG00000119638
CONAN: Copy Number AnalysisNEK9 
Mutations
ICGC Data PortalNEK9 
TCGA Data PortalNEK9 
Broad Tumor PortalNEK9
OASIS PortalNEK9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNEK9  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNEK9
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NEK9
DgiDB (Drug Gene Interaction Database)NEK9
DoCM (Curated mutations)NEK9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NEK9 (select a term)
intoGenNEK9
Cancer3DNEK9(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609798   
Orphanet10858   
MedgenNEK9
Genetic Testing Registry NEK9
NextProtQ8TD19 [Medical]
TSGene91754
GENETestsNEK9
Huge Navigator NEK9 [HugePedia]
snp3D : Map Gene to Disease91754
BioCentury BCIQNEK9
ClinGenNEK9
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD91754
Chemical/Pharm GKB GenePA38593
Clinical trialNEK9
Miscellaneous
canSAR (ICR)NEK9 (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNEK9
EVEXNEK9
GoPubMedNEK9
iHOPNEK9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:18:37 CET 2017

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