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NELFA (negative elongation factor complex member A)

Identity

Alias_namesWHSC2
Wolf-Hirschhorn syndrome candidate 2
Alias_symbol (synonym)NELF-A
Other aliasP/OKcl.15
HGNC (Hugo) NELFA
LocusID (NCBI) 7469
Atlas_Id 42811
Location 4p16.3  [Link to chromosome band 4p16]
Location_base_pair Starts at 1984441 and ends at 2010962 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NELFA   12768
Cards
Entrez_Gene (NCBI)NELFA  7469  negative elongation factor complex member A
AliasesNELF-A; P/OKcl.15; WHSC2
GeneCards (Weizmann)NELFA
Ensembl hg19 (Hinxton)ENSG00000185049 [Gene_View]  chr4:1984441-2010962 [Contig_View]  NELFA [Vega]
Ensembl hg38 (Hinxton)ENSG00000185049 [Gene_View]  chr4:1984441-2010962 [Contig_View]  NELFA [Vega]
ICGC DataPortalENSG00000185049
TCGA cBioPortalNELFA
AceView (NCBI)NELFA
Genatlas (Paris)NELFA
WikiGenes7469
SOURCE (Princeton)NELFA
Genetics Home Reference (NIH)NELFA
Genomic and cartography
GoldenPath hg19 (UCSC)NELFA  -     chr4:1984441-2010962 -  4p16.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)NELFA  -     4p16.3   [Description]    (hg38-Dec_2013)
EnsemblNELFA - 4p16.3 [CytoView hg19]  NELFA - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBINELFA [Mapview hg19]  NELFA [Mapview hg38]
OMIM606026   
Gene and transcription
Genbank (Entrez)AB044549 AF101434 AF131751 AI218582 AI560345
RefSeq transcript (Entrez)NM_005663
RefSeq genomic (Entrez)NC_000004 NC_018915 NG_009232 NT_006051 NW_004929314
Consensus coding sequences : CCDS (NCBI)NELFA
Cluster EST : UnigeneHs.21771 [ NCBI ]
CGAP (NCI)Hs.21771
Alternative Splicing GalleryENSG00000185049
Gene ExpressionNELFA [ NCBI-GEO ]   NELFA [ EBI - ARRAY_EXPRESS ]   NELFA [ SEEK ]   NELFA [ MEM ]
Gene Expression Viewer (FireBrowse)NELFA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7469
GTEX Portal (Tissue expression)NELFA
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H3P2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H3P2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H3P2
Splice isoforms : SwissVarQ9H3P2
PhosPhoSitePlusQ9H3P2
Domains : Interpro (EBI)NELF-A   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)NELFA
DMDM Disease mutations7469
Blocks (Seattle)NELFA
SuperfamilyQ9H3P2
Human Protein AtlasENSG00000185049
Peptide AtlasQ9H3P2
HPRD12080
IPIIPI00643383   IPI01011851   IPI00394679   IPI00926414   IPI00926012   IPI00925762   IPI00927343   IPI00927200   IPI00926921   IPI00970857   IPI00927834   
Protein Interaction databases
DIP (DOE-UCLA)Q9H3P2
IntAct (EBI)Q9H3P2
FunCoupENSG00000185049
BioGRIDNELFA
STRING (EMBL)NELFA
ZODIACNELFA
Ontologies - Pathways
QuickGOQ9H3P2
Ontology : AmiGOprotein binding  nucleoplasm  nucleoplasm  cytoplasm  transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  multicellular organism development  NELF complex  negative regulation of transcription elongation from RNA polymerase II promoter  positive regulation of viral transcription  
Ontology : EGO-EBIprotein binding  nucleoplasm  nucleoplasm  cytoplasm  transcription from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  multicellular organism development  NELF complex  negative regulation of transcription elongation from RNA polymerase II promoter  positive regulation of viral transcription  
NDEx NetworkNELFA
Atlas of Cancer Signalling NetworkNELFA
Wikipedia pathwaysNELFA
Orthology - Evolution
OrthoDB7469
GeneTree (enSembl)ENSG00000185049
Phylogenetic Trees/Animal Genes : TreeFamNELFA
HOVERGENQ9H3P2
HOGENOMQ9H3P2
Homologs : HomoloGeneNELFA
Homology/Alignments : Family Browser (UCSC)NELFA
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNELFA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NELFA
dbVarNELFA
ClinVarNELFA
1000_GenomesNELFA 
Exome Variant ServerNELFA
ExAC (Exome Aggregation Consortium)NELFA (select the gene name)
Genetic variants : HAPMAP7469
Genomic Variants (DGV)NELFA [DGVbeta]
DECIPHER (Syndromes)4:1984441-2010962  ENSG00000185049
CONAN: Copy Number AnalysisNELFA 
Mutations
ICGC Data PortalNELFA 
TCGA Data PortalNELFA 
Broad Tumor PortalNELFA
OASIS PortalNELFA [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDNELFA
BioMutasearch NELFA
DgiDB (Drug Gene Interaction Database)NELFA
DoCM (Curated mutations)NELFA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NELFA (select a term)
intoGenNELFA
Cancer3DNELFA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606026   
Orphanet147   
MedgenNELFA
Genetic Testing Registry NELFA
NextProtQ9H3P2 [Medical]
TSGene7469
GENETestsNELFA
Huge Navigator NELFA [HugePedia]
snp3D : Map Gene to Disease7469
BioCentury BCIQNELFA
ClinGenNELFA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7469
Chemical/Pharm GKB GenePA37371
Clinical trialNELFA
Miscellaneous
canSAR (ICR)NELFA (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNELFA
EVEXNELFA
GoPubMedNELFA
iHOPNELFA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:18:37 CET 2017

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