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NELFCD (negative elongation factor complex member C/D)

Identity

Alias (NCBI)HSPC130
NELF-C
NELF-D
TH1
TH1L
HGNC (Hugo) NELFCD
HGNC Alias symbHSPC130
TH1
NELF-C
NELF-D
HGNC Alias nametrihydrophobin 1
HGNC Previous nameTH1L
HGNC Previous nameTH1-like (Drosophila homolog)
 TH1-like (Drosophila)
LocusID (NCBI) 51497
Atlas_Id 51720
Location 20q13.32  [Link to chromosome band 20q13]
Location_base_pair Starts at 58981256 and ends at 58995113 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NELFCD   15934
Cards
Entrez_Gene (NCBI)NELFCD  51497  negative elongation factor complex member C/D
AliasesHSPC130; NELF-C; NELF-D; TH1; 
TH1L
GeneCards (Weizmann)NELFCD
Ensembl hg19 (Hinxton)ENSG00000101158 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101158 [Gene_View]  ENSG00000101158 [Sequence]  chr20:58981256-58995113 [Contig_View]  NELFCD [Vega]
ICGC DataPortalENSG00000101158
TCGA cBioPortalNELFCD
AceView (NCBI)NELFCD
Genatlas (Paris)NELFCD
WikiGenes51497
SOURCE (Princeton)NELFCD
Genetics Home Reference (NIH)NELFCD
Genomic and cartography
GoldenPath hg38 (UCSC)NELFCD  -     chr20:58981256-58995113 +  20q13.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NELFCD  -     20q13.32   [Description]    (hg19-Feb_2009)
GoldenPathNELFCD - 20q13.32 [CytoView hg19]  NELFCD - 20q13.32 [CytoView hg38]
ImmunoBaseENSG00000101158
genome Data Viewer NCBINELFCD [Mapview hg19]  
OMIM605297   
Gene and transcription
Genbank (Entrez)AA831111 AF161479 AJ238374 AJ238375 AJ238376
RefSeq transcript (Entrez)NM_016397 NM_198976
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NELFCD
Alternative Splicing GalleryENSG00000101158
Gene ExpressionNELFCD [ NCBI-GEO ]   NELFCD [ EBI - ARRAY_EXPRESS ]   NELFCD [ SEEK ]   NELFCD [ MEM ]
Gene Expression Viewer (FireBrowse)NELFCD [ Firebrowse - Broad ]
GenevisibleExpression of NELFCD in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51497
GTEX Portal (Tissue expression)NELFCD
Human Protein AtlasENSG00000101158-NELFCD [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IXH7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IXH7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IXH7
Splice isoforms : SwissVarQ8IXH7
PhosPhoSitePlusQ8IXH7
Domains : Interpro (EBI)TH1   
Domain families : Pfam (Sanger)TH1 (PF04858)   
Domain families : Pfam (NCBI)pfam04858   
Conserved Domain (NCBI)NELFCD
DMDM Disease mutations51497
Blocks (Seattle)NELFCD
PDB (RSDB)5L3X    6GML   
PDB Europe5L3X    6GML   
PDB (PDBSum)5L3X    6GML   
PDB (IMB)5L3X    6GML   
Structural Biology KnowledgeBase5L3X    6GML   
SCOP (Structural Classification of Proteins)5L3X    6GML   
CATH (Classification of proteins structures)5L3X    6GML   
SuperfamilyQ8IXH7
Human Protein Atlas [tissue]ENSG00000101158-NELFCD [tissue]
Peptide AtlasQ8IXH7
HPRD16096
IPIIPI00387090   IPI00759539   IPI00164949   
Protein Interaction databases
DIP (DOE-UCLA)Q8IXH7
IntAct (EBI)Q8IXH7
FunCoupENSG00000101158
BioGRIDNELFCD
STRING (EMBL)NELFCD
ZODIACNELFCD
Ontologies - Pathways
QuickGOQ8IXH7
Ontology : AmiGORNA binding  protein binding  nucleoplasm  transcription by RNA polymerase II  transcription elongation from RNA polymerase II promoter  membrane  NELF complex  NELF complex  negative regulation of transcription elongation from RNA polymerase II promoter  positive regulation of viral transcription  
Ontology : EGO-EBIRNA binding  protein binding  nucleoplasm  transcription by RNA polymerase II  transcription elongation from RNA polymerase II promoter  membrane  NELF complex  NELF complex  negative regulation of transcription elongation from RNA polymerase II promoter  positive regulation of viral transcription  
NDEx NetworkNELFCD
Atlas of Cancer Signalling NetworkNELFCD
Wikipedia pathwaysNELFCD
Orthology - Evolution
OrthoDB51497
GeneTree (enSembl)ENSG00000101158
Phylogenetic Trees/Animal Genes : TreeFamNELFCD
HOGENOMQ8IXH7
Homologs : HomoloGeneNELFCD
Homology/Alignments : Family Browser (UCSC)NELFCD
Gene fusions - Rearrangements
Fusion : QuiverNELFCD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNELFCD [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NELFCD
dbVarNELFCD
ClinVarNELFCD
1000_GenomesNELFCD 
Exome Variant ServerNELFCD
GNOMAD BrowserENSG00000101158
Varsome BrowserNELFCD
Genetic variants : HAPMAP51497
Genomic Variants (DGV)NELFCD [DGVbeta]
DECIPHERNELFCD [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNELFCD 
Mutations
ICGC Data PortalNELFCD 
TCGA Data PortalNELFCD 
Broad Tumor PortalNELFCD
OASIS PortalNELFCD [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNELFCD  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DNELFCD
Mutations and Diseases : HGMDNELFCD
BioMutasearch NELFCD
DgiDB (Drug Gene Interaction Database)NELFCD
DoCM (Curated mutations)NELFCD (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NELFCD (select a term)
intoGenNELFCD
Cancer3DNELFCD(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605297   
Orphanet
DisGeNETNELFCD
MedgenNELFCD
Genetic Testing Registry NELFCD
NextProtQ8IXH7 [Medical]
TSGene51497
GENETestsNELFCD
Target ValidationNELFCD
Huge Navigator NELFCD [HugePedia]
snp3D : Map Gene to Disease51497
BioCentury BCIQNELFCD
ClinGenNELFCD
Clinical trials, drugs, therapy
Protein Interactions : CTD51497
Pharm GKB GenePA38055
Clinical trialNELFCD
Miscellaneous
canSAR (ICR)NELFCD (select the gene name)
HarmonizomeNELFCD
DataMed IndexNELFCD
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNELFCD
EVEXNELFCD
GoPubMedNELFCD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jul 16 15:26:59 CEST 2020

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