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NEU2 (neuraminidase 2)

Identity

Alias_namessialidase 2 (cytosolic sialidase)
neuraminidase 2 (cytosolic sialidase)
Alias_symbol (synonym)SIAL2
Other alias
HGNC (Hugo) NEU2
LocusID (NCBI) 4759
Atlas_Id 51252
Location 2q37.1  [Link to chromosome band 2q37]
Location_base_pair Starts at 233032672 and ends at 233035057 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NEU2   7759
Cards
Entrez_Gene (NCBI)NEU2  4759  neuraminidase 2
AliasesSIAL2
GeneCards (Weizmann)NEU2
Ensembl hg19 (Hinxton)ENSG00000115488 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115488 [Gene_View]  chr2:233032672-233035057 [Contig_View]  NEU2 [Vega]
ICGC DataPortalENSG00000115488
TCGA cBioPortalNEU2
AceView (NCBI)NEU2
Genatlas (Paris)NEU2
WikiGenes4759
SOURCE (Princeton)NEU2
Genetics Home Reference (NIH)NEU2
Genomic and cartography
GoldenPath hg38 (UCSC)NEU2  -     chr2:233032672-233035057 +  2q37.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NEU2  -     2q37.1   [Description]    (hg19-Feb_2009)
EnsemblNEU2 - 2q37.1 [CytoView hg19]  NEU2 - 2q37.1 [CytoView hg38]
Mapping of homologs : NCBINEU2 [Mapview hg19]  NEU2 [Mapview hg38]
OMIM605528   
Gene and transcription
Genbank (Entrez)BC069151 BC107053
RefSeq transcript (Entrez)NM_005383
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)NEU2
Cluster EST : UnigeneHs.532681 [ NCBI ]
CGAP (NCI)Hs.532681
Alternative Splicing GalleryENSG00000115488
Gene ExpressionNEU2 [ NCBI-GEO ]   NEU2 [ EBI - ARRAY_EXPRESS ]   NEU2 [ SEEK ]   NEU2 [ MEM ]
Gene Expression Viewer (FireBrowse)NEU2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)4759
GTEX Portal (Tissue expression)NEU2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3R4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y3R4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3R4
Splice isoforms : SwissVarQ9Y3R4
Catalytic activity : Enzyme3.2.1.18 [ Enzyme-Expasy ]   3.2.1.183.2.1.18 [ IntEnz-EBI ]   3.2.1.18 [ BRENDA ]   3.2.1.18 [ KEGG ]   
PhosPhoSitePlusQ9Y3R4
Domains : Interpro (EBI)Sialidase-2    Sialidase_fam    Sialidases   
Domain families : Pfam (Sanger)BNR_2 (PF13088)   
Domain families : Pfam (NCBI)pfam13088   
Conserved Domain (NCBI)NEU2
DMDM Disease mutations4759
Blocks (Seattle)NEU2
PDB (SRS)1SNT    1SO7    1VCU    2F0Z    2F10    2F11    2F12    2F13    2F24    2F25    2F26    2F27    2F28    2F29    4NC5    4NCS   
PDB (PDBSum)1SNT    1SO7    1VCU    2F0Z    2F10    2F11    2F12    2F13    2F24    2F25    2F26    2F27    2F28    2F29    4NC5    4NCS   
PDB (IMB)1SNT    1SO7    1VCU    2F0Z    2F10    2F11    2F12    2F13    2F24    2F25    2F26    2F27    2F28    2F29    4NC5    4NCS   
PDB (RSDB)1SNT    1SO7    1VCU    2F0Z    2F10    2F11    2F12    2F13    2F24    2F25    2F26    2F27    2F28    2F29    4NC5    4NCS   
Structural Biology KnowledgeBase1SNT    1SO7    1VCU    2F0Z    2F10    2F11    2F12    2F13    2F24    2F25    2F26    2F27    2F28    2F29    4NC5    4NCS   
SCOP (Structural Classification of Proteins)1SNT    1SO7    1VCU    2F0Z    2F10    2F11    2F12    2F13    2F24    2F25    2F26    2F27    2F28    2F29    4NC5    4NCS   
CATH (Classification of proteins structures)1SNT    1SO7    1VCU    2F0Z    2F10    2F11    2F12    2F13    2F24    2F25    2F26    2F27    2F28    2F29    4NC5    4NCS   
SuperfamilyQ9Y3R4
Human Protein AtlasENSG00000115488
Peptide AtlasQ9Y3R4
HPRD05702
IPIIPI00022482   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3R4
IntAct (EBI)Q9Y3R4
FunCoupENSG00000115488
BioGRIDNEU2
STRING (EMBL)NEU2
ZODIACNEU2
Ontologies - Pathways
QuickGOQ9Y3R4
Ontology : AmiGOexo-alpha-sialidase activity  exo-alpha-sialidase activity  protein binding  cytoplasm  cytosol  cytosol  glycosphingolipid metabolic process  ganglioside catabolic process  oligosaccharide catabolic process  membrane  intracellular membrane-bounded organelle  cellular oligosaccharide catabolic process  exo-alpha-(2->3)-sialidase activity  exo-alpha-(2->6)-sialidase activity  exo-alpha-(2->8)-sialidase activity  catalytic complex  
Ontology : EGO-EBIexo-alpha-sialidase activity  exo-alpha-sialidase activity  protein binding  cytoplasm  cytosol  cytosol  glycosphingolipid metabolic process  ganglioside catabolic process  oligosaccharide catabolic process  membrane  intracellular membrane-bounded organelle  cellular oligosaccharide catabolic process  exo-alpha-(2->3)-sialidase activity  exo-alpha-(2->6)-sialidase activity  exo-alpha-(2->8)-sialidase activity  catalytic complex  
Pathways : KEGGOther glycan degradation    Sphingolipid metabolism   
NDEx NetworkNEU2
Atlas of Cancer Signalling NetworkNEU2
Wikipedia pathwaysNEU2
Orthology - Evolution
OrthoDB4759
GeneTree (enSembl)ENSG00000115488
Phylogenetic Trees/Animal Genes : TreeFamNEU2
HOVERGENQ9Y3R4
HOGENOMQ9Y3R4
Homologs : HomoloGeneNEU2
Homology/Alignments : Family Browser (UCSC)NEU2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNEU2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NEU2
dbVarNEU2
ClinVarNEU2
1000_GenomesNEU2 
Exome Variant ServerNEU2
ExAC (Exome Aggregation Consortium)NEU2 (select the gene name)
Genetic variants : HAPMAP4759
Genomic Variants (DGV)NEU2 [DGVbeta]
DECIPHERNEU2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNEU2 
Mutations
ICGC Data PortalNEU2 
TCGA Data PortalNEU2 
Broad Tumor PortalNEU2
OASIS PortalNEU2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNEU2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNEU2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch NEU2
DgiDB (Drug Gene Interaction Database)NEU2
DoCM (Curated mutations)NEU2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NEU2 (select a term)
intoGenNEU2
Cancer3DNEU2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605528   
Orphanet
MedgenNEU2
Genetic Testing Registry NEU2
NextProtQ9Y3R4 [Medical]
TSGene4759
GENETestsNEU2
Target ValidationNEU2
Huge Navigator NEU2 [HugePedia]
snp3D : Map Gene to Disease4759
BioCentury BCIQNEU2
ClinGenNEU2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD4759
Chemical/Pharm GKB GenePA31561
Clinical trialNEU2
Miscellaneous
canSAR (ICR)NEU2 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNEU2
EVEXNEU2
GoPubMedNEU2
iHOPNEU2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 17:08:59 CEST 2017

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