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NEU4 (neuraminidase 4)

Identity

Alias_namessialidase 4
neuraminidase 4 (sialidase)
Other alias-
HGNC (Hugo) NEU4
LocusID (NCBI) 129807
Atlas_Id 50718
Location 2q37.3  [Link to chromosome band 2q37]
Location_base_pair Starts at 241810932 and ends at 241817413 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)NEU4   21328
Cards
Entrez_Gene (NCBI)NEU4  129807  neuraminidase 4
Aliases
GeneCards (Weizmann)NEU4
Ensembl hg19 (Hinxton)ENSG00000204099 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204099 [Gene_View]  chr2:241810932-241817413 [Contig_View]  NEU4 [Vega]
ICGC DataPortalENSG00000204099
TCGA cBioPortalNEU4
AceView (NCBI)NEU4
Genatlas (Paris)NEU4
WikiGenes129807
SOURCE (Princeton)NEU4
Genetics Home Reference (NIH)NEU4
Genomic and cartography
GoldenPath hg38 (UCSC)NEU4  -     chr2:241810932-241817413 +  2q37.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)NEU4  -     2q37.3   [Description]    (hg19-Feb_2009)
EnsemblNEU4 - 2q37.3 [CytoView hg19]  NEU4 - 2q37.3 [CytoView hg38]
Mapping of homologs : NCBINEU4 [Mapview hg19]  NEU4 [Mapview hg38]
OMIM608527   
Gene and transcription
Genbank (Entrez)AJ277883 AK025617 AK091038 AK096992 AK289421
RefSeq transcript (Entrez)NM_001167599 NM_001167600 NM_001167601 NM_001167602 NM_080741
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_187527
Consensus coding sequences : CCDS (NCBI)NEU4
Cluster EST : UnigeneHs.551747 [ NCBI ]
CGAP (NCI)Hs.551747
Alternative Splicing GalleryENSG00000204099
Gene ExpressionNEU4 [ NCBI-GEO ]   NEU4 [ EBI - ARRAY_EXPRESS ]   NEU4 [ SEEK ]   NEU4 [ MEM ]
Gene Expression Viewer (FireBrowse)NEU4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)129807
GTEX Portal (Tissue expression)NEU4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WWR8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WWR8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WWR8
Splice isoforms : SwissVarQ8WWR8
Catalytic activity : Enzyme3.2.1.18 [ Enzyme-Expasy ]   3.2.1.183.2.1.18 [ IntEnz-EBI ]   3.2.1.18 [ BRENDA ]   3.2.1.18 [ KEGG ]   
PhosPhoSitePlusQ8WWR8
Domains : Interpro (EBI)Sialidase-4    Sialidase_fam    Sialidases   
Domain families : Pfam (Sanger)BNR_2 (PF13088)   
Domain families : Pfam (NCBI)pfam13088   
Conserved Domain (NCBI)NEU4
DMDM Disease mutations129807
Blocks (Seattle)NEU4
SuperfamilyQ8WWR8
Human Protein AtlasENSG00000204099
Peptide AtlasQ8WWR8
HPRD12249
IPIIPI00954297   IPI00790962   IPI00922332   IPI00930740   IPI00893103   IPI00892845   IPI00892951   IPI00892642   IPI00892762   IPI00892753   IPI01014725   IPI00894541   
Protein Interaction databases
DIP (DOE-UCLA)Q8WWR8
IntAct (EBI)Q8WWR8
FunCoupENSG00000204099
BioGRIDNEU4
STRING (EMBL)NEU4
ZODIACNEU4
Ontologies - Pathways
QuickGOQ8WWR8
Ontology : AmiGOexo-alpha-sialidase activity  exo-alpha-sialidase activity  protein binding  mitochondrion  lysosome  lysosome  glycoprotein catabolic process  glycosphingolipid metabolic process  ganglioside catabolic process  oligosaccharide catabolic process  organelle inner membrane  lysosomal lumen  exo-alpha-(2->3)-sialidase activity  exo-alpha-(2->6)-sialidase activity  exo-alpha-(2->8)-sialidase activity  
Ontology : EGO-EBIexo-alpha-sialidase activity  exo-alpha-sialidase activity  protein binding  mitochondrion  lysosome  lysosome  glycoprotein catabolic process  glycosphingolipid metabolic process  ganglioside catabolic process  oligosaccharide catabolic process  organelle inner membrane  lysosomal lumen  exo-alpha-(2->3)-sialidase activity  exo-alpha-(2->6)-sialidase activity  exo-alpha-(2->8)-sialidase activity  
Pathways : KEGGOther glycan degradation    Sphingolipid metabolism   
NDEx NetworkNEU4
Atlas of Cancer Signalling NetworkNEU4
Wikipedia pathwaysNEU4
Orthology - Evolution
OrthoDB129807
GeneTree (enSembl)ENSG00000204099
Phylogenetic Trees/Animal Genes : TreeFamNEU4
HOVERGENQ8WWR8
HOGENOMQ8WWR8
Homologs : HomoloGeneNEU4
Homology/Alignments : Family Browser (UCSC)NEU4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerNEU4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)NEU4
dbVarNEU4
ClinVarNEU4
1000_GenomesNEU4 
Exome Variant ServerNEU4
ExAC (Exome Aggregation Consortium)NEU4 (select the gene name)
Genetic variants : HAPMAP129807
Genomic Variants (DGV)NEU4 [DGVbeta]
DECIPHERNEU4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisNEU4 
Mutations
ICGC Data PortalNEU4 
TCGA Data PortalNEU4 
Broad Tumor PortalNEU4
OASIS PortalNEU4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICNEU4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDNEU4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch NEU4
DgiDB (Drug Gene Interaction Database)NEU4
DoCM (Curated mutations)NEU4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)NEU4 (select a term)
intoGenNEU4
Cancer3DNEU4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608527   
Orphanet
MedgenNEU4
Genetic Testing Registry NEU4
NextProtQ8WWR8 [Medical]
TSGene129807
GENETestsNEU4
Target ValidationNEU4
Huge Navigator NEU4 [HugePedia]
snp3D : Map Gene to Disease129807
BioCentury BCIQNEU4
ClinGenNEU4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD129807
Chemical/Pharm GKB GenePA134917116
Clinical trialNEU4
Miscellaneous
canSAR (ICR)NEU4 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineNEU4
EVEXNEU4
GoPubMedNEU4
iHOPNEU4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:46:40 CEST 2017

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